transmembrane receptor protein tyrosine kinase signaling pathway Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell where the receptor possesses tyrosine kinase activity, and ending with regulation of a downstream cellular process, e.g. transcription. (Gene Ontology, GO_0007169)
External Link http://amigo.geneontology.org/amigo/term/GO:0007169
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Genes

643 genes participating in the transmembrane receptor protein tyrosine kinase signaling pathway biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
AATF apoptosis antagonizing transcription factor
ABI1 abl-interactor 1
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ABR active BCR-related
ACTB actin, beta
ACTG1 actin gamma 1
ACTR2 ARP2 actin-related protein 2 homolog (yeast)
ACTR3 ARP3 actin-related protein 3 homolog (yeast)
ADAM10 ADAM metallopeptidase domain 10
ADAM12 ADAM metallopeptidase domain 12
ADAM17 ADAM metallopeptidase domain 17
ADCY1 adenylate cyclase 1 (brain)
ADCY2 adenylate cyclase 2 (brain)
ADCY3 adenylate cyclase 3
ADCY4 adenylate cyclase 4
ADCY5 adenylate cyclase 5
ADCY6 adenylate cyclase 6
ADCY7 adenylate cyclase 7
ADCY8 adenylate cyclase 8 (brain)
ADCY9 adenylate cyclase 9
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I
ADORA2A adenosine A2a receptor
ADRBK1 adrenergic, beta, receptor kinase 1
AGO1 argonaute RISC catalytic component 1
AGO2 argonaute RISC catalytic component 2
AGO3 argonaute RISC catalytic component 3
AGO4 argonaute RISC catalytic component 4
AHI1 Abelson helper integration site 1
AKAP13 A kinase (PRKA) anchor protein 13
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT1S1 AKT1 substrate 1 (proline-rich)
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALK anaplastic lymphoma receptor tyrosine kinase
ANGPT1 angiopoietin 1
ANGPT2 angiopoietin 2
ANGPTL1 angiopoietin-like 1
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A
AP2A1 adaptor-related protein complex 2, alpha 1 subunit
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
AP2B1 adaptor-related protein complex 2, beta 1 subunit
AP2M1 adaptor-related protein complex 2, mu 1 subunit
AP2S1 adaptor-related protein complex 2, sigma 1 subunit
AP3S1 adaptor-related protein complex 3, sigma 1 subunit
APH1A APH1A gamma secretase subunit
APH1B APH1B gamma secretase subunit
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
AREG amphiregulin
ARF4 ADP-ribosylation factor 4
ARHGAP4 Rho GTPase activating protein 4
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9
ARID5B AT rich interactive domain 5B (MRF1-like)
ARPC1A actin related protein 2/3 complex, subunit 1A, 41kDa
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa
ATF1 activating transcription factor 1
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
ATP6V0C ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1
ATP6V0D2 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
ATP6V0E2 ATPase, H+ transporting V0 subunit e2
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
ATP6V1C2 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1
ATP6V1E2 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2
ATP6V1F ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
ATP6V1G3 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
AXL AXL receptor tyrosine kinase
BAD BCL2-associated agonist of cell death
BAIAP2 BAI1-associated protein 2
BCAR1 breast cancer anti-estrogen resistance 1
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BCR breakpoint cluster region
BDKRB2 bradykinin receptor B2
BDNF brain-derived neurotrophic factor
BLK BLK proto-oncogene, Src family tyrosine kinase
BLNK B-cell linker
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
BMX BMX non-receptor tyrosine kinase
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRK1 BRICK1, SCAR/WAVE actin-nucleating complex subunit
BTC betacellulin
BTK Bruton agammaglobulinemia tyrosine kinase
C2CD5 C2 calcium-dependent domain containing 5
CAB39 calcium binding protein 39
CAB39L calcium binding protein 39-like
CAMK4 calcium/calmodulin-dependent protein kinase IV
CAMLG calcium modulating ligand
CASP2 caspase 2, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CAV2 caveolin 2
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCL2 chemokine (C-C motif) ligand 2
CD19 CD19 molecule
CD28 CD28 molecule
CD3E CD3e molecule, epsilon (CD3-TCR complex)
CD3EAP CD3e molecule, epsilon associated protein
CD4 CD4 molecule
CD7 CD7 molecule
CD80 CD80 molecule
CD86 CD86 molecule
CD8A CD8a molecule
CD8B CD8b molecule
CDC42 cell division cycle 42
CDH5 cadherin 5, type 2 (vascular endothelium)
CDK1 cyclin-dependent kinase 1
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CEP57 centrosomal protein 57kDa
CFL1 cofilin 1 (non-muscle)
CHN1 chimerin 1
CHUK conserved helix-loop-helix ubiquitous kinase
CLNK cytokine-dependent hematopoietic cell linker
CLTA clathrin, light chain A
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CREB1 cAMP responsive element binding protein 1
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CSF1R colony stimulating factor 1 receptor
CSK c-src tyrosine kinase
CSPG4 chondroitin sulfate proteoglycan 4
CSRNP1 cysteine-serine-rich nuclear protein 1
CTGF connective tissue growth factor
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CTNND1 catenin (cadherin-associated protein), delta 1
CYBA cytochrome b-245, alpha polypeptide
CYBB cytochrome b-245, beta polypeptide
CYFIP2 cytoplasmic FMR1 interacting protein 2
DAB2IP DAB2 interacting protein
DDIT4 DNA-damage-inducible transcript 4
DDR1 discoidin domain receptor tyrosine kinase 1
DDR2 discoidin domain receptor tyrosine kinase 2
DGKD diacylglycerol kinase, delta 130kDa
DNAL4 dynein, axonemal, light chain 4
DNM1 dynamin 1
DOCK1 dedicator of cytokinesis 1
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DOK2 docking protein 2, 56kDa
DOK4 docking protein 4
DOK5 docking protein 5
DUSP3 dual specificity phosphatase 3
DUSP4 dual specificity phosphatase 4
DUSP6 dual specificity phosphatase 6
DUSP7 dual specificity phosphatase 7
ECT2 epithelial cell transforming 2
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EFNA1 ephrin-A1
EFNA2 ephrin-A2
EFNA3 ephrin-A3
EFNA4 ephrin-A4
EFNA5 ephrin-A5
EFNB1 ephrin-B1
EFNB2 ephrin-B2
EFNB3 ephrin-B3
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
EIF4B eukaryotic translation initiation factor 4B
EIF4E eukaryotic translation initiation factor 4E
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
ELK1 ELK1, member of ETS oncogene family
ELMO1 engulfment and cell motility 1
ELMO2 engulfment and cell motility 2
EPHA1 EPH receptor A1
EPHA10 EPH receptor A10
EPHA2 EPH receptor A2
EPHA3 EPH receptor A3
EPHA4 EPH receptor A4
EPHA5 EPH receptor A5
EPHA6 EPH receptor A6
EPHA7 EPH receptor A7
EPHA8 EPH receptor A8
EPHB1 EPH receptor B1
EPHB2 EPH receptor B2
EPHB3 EPH receptor B3
EPHB4 EPH receptor B4
EPHB6 EPH receptor B6
EPN1 epsin 1
EPS15 epidermal growth factor receptor pathway substrate 15
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1
EPS8 epidermal growth factor receptor pathway substrate 8
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB2IP erbb2 interacting protein
ERBB3 erb-b2 receptor tyrosine kinase 3
ERBB4 erb-b2 receptor tyrosine kinase 4
EREG epiregulin
FER fer (fps/fes related) tyrosine kinase
FES FES proto-oncogene, tyrosine kinase
FGD1 FYVE, RhoGEF and PH domain containing 1
FGD2 FYVE, RhoGEF and PH domain containing 2
FGD3 FYVE, RhoGEF and PH domain containing 3
FGD4 FYVE, RhoGEF and PH domain containing 4
FGF1 fibroblast growth factor 1 (acidic)
FGF10 fibroblast growth factor 10
FGF12 fibroblast growth factor 12
FGF16 fibroblast growth factor 16
FGF17 fibroblast growth factor 17
FGF18 fibroblast growth factor 18
FGF19 fibroblast growth factor 19
FGF2 fibroblast growth factor 2 (basic)
FGF20 fibroblast growth factor 20
FGF21 fibroblast growth factor 21
FGF22 fibroblast growth factor 22
FGF23 fibroblast growth factor 23
FGF3 fibroblast growth factor 3
FGF4 fibroblast growth factor 4
FGF5 fibroblast growth factor 5
FGF6 fibroblast growth factor 6
FGF7 fibroblast growth factor 7
FGF8 fibroblast growth factor 8 (androgen-induced)
FGF9 fibroblast growth factor 9
FGFR1 fibroblast growth factor receptor 1
FGFR2 fibroblast growth factor receptor 2
FGFR3 fibroblast growth factor receptor 3
FGFR4 fibroblast growth factor receptor 4
FGFRL1 fibroblast growth factor receptor-like 1
FGR FGR proto-oncogene, Src family tyrosine kinase
FIBP fibroblast growth factor (acidic) intracellular binding protein
FIGF c-fos induced growth factor (vascular endothelial growth factor D)
FLT1 fms-related tyrosine kinase 1
FLT3 fms-related tyrosine kinase 3
FLT4 fms-related tyrosine kinase 4
FOXC1 forkhead box C1
FOXC2 forkhead box C2
FOXO1 forkhead box O1
FOXO3 forkhead box O3
FOXO4 forkhead box O4
FRK fyn-related Src family tyrosine kinase
FRS2 fibroblast growth factor receptor substrate 2
FRS3 fibroblast growth factor receptor substrate 3
FURIN furin (paired basic amino acid cleaving enzyme)
FYN FYN proto-oncogene, Src family tyrosine kinase
GAB1 GRB2-associated binding protein 1
GAB2 GRB2-associated binding protein 2
GAREM GRB2 associated, regulator of MAPK1
GFRA1 GDNF family receptor alpha 1
GFRA2 GDNF family receptor alpha 2
GFRA4 GDNF family receptor alpha 4
GH1 growth hormone 1
GHR growth hormone receptor
GIGYF1 GRB10 interacting GYF protein 1
GIGYF2 GRB10 interacting GYF protein 2
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GRB10 growth factor receptor-bound protein 10
GRB2 growth factor receptor-bound protein 2
GRB7 growth factor receptor-bound protein 7
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
HAP1 huntingtin-associated protein 1
HBEGF heparin-binding EGF-like growth factor
HCK HCK proto-oncogene, Src family tyrosine kinase
HDAC1 histone deacetylase 1
HDAC2 histone deacetylase 2
HDAC3 histone deacetylase 3
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HGS hepatocyte growth factor-regulated tyrosine kinase substrate
HRAS Harvey rat sarcoma viral oncogene homolog
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPB1 heat shock 27kDa protein 1
IDE insulin-degrading enzyme
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGF2 insulin-like growth factor 2
IGF2R insulin-like growth factor 2 receptor
IGFBP1 insulin-like growth factor binding protein 1
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IL31RA interleukin 31 receptor A
INS insulin
INSR insulin receptor
INSRR insulin receptor-related receptor
IQGAP1 IQ motif containing GTPase activating protein 1
IRAK1 interleukin-1 receptor-associated kinase 1
IRS1 insulin receptor substrate 1
IRS2 insulin receptor substrate 2
IRS4 insulin receptor substrate 4
ITGAV integrin, alpha V
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITGB3BP integrin beta 3 binding protein (beta3-endonexin)
ITK IL2-inducible T-cell kinase
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
ITSN1 intersectin 1 (SH3 domain protein)
JAK1 Janus kinase 1
JAK2 Janus kinase 2
JAK3 Janus kinase 3
JUP junction plakoglobin
KALRN kalirin, RhoGEF kinase
KDR kinase insert domain receptor
KIDINS220 kinase D-interacting substrate, 220kDa
KIF16B kinesin family member 16B
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KITLG KIT ligand
KL klotho
KLB klotho beta
KRAS Kirsten rat sarcoma viral oncogene homolog
LCK LCK proto-oncogene, Src family tyrosine kinase
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
LIMK1 LIM domain kinase 1
LINGO1 leucine rich repeat and Ig domain containing 1
LTK leukocyte receptor tyrosine kinase
LYN LYN proto-oncogene, Src family tyrosine kinase
MAG myelin associated glycoprotein
MAGED1 melanoma antigen family D1
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAP2K5 mitogen-activated protein kinase kinase 5
MAPK1 mitogen-activated protein kinase 1
MAPK11 mitogen-activated protein kinase 11
MAPK12 mitogen-activated protein kinase 12
MAPK13 mitogen-activated protein kinase 13
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK7 mitogen-activated protein kinase 7
MAPK8 mitogen-activated protein kinase 8
MAPKAP1 mitogen-activated protein kinase associated protein 1
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3
MATK megakaryocyte-associated tyrosine kinase
MCF2 MCF.2 cell line derived transforming sequence
MCF2L MCF.2 cell line derived transforming sequence-like
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MEF2A myocyte enhancer factor 2A
MEF2C myocyte enhancer factor 2C
MET MET proto-oncogene, receptor tyrosine kinase
MKNK1 MAP kinase interacting serine/threonine kinase 1
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae)
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MOV10 Mov10 RISC complex RNA helicase
MPZL1 myelin protein zero-like 1
MST1R macrophage stimulating 1 receptor
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MTSS1 metastasis suppressor 1
MUC20 mucin 20, cell surface associated
MUSK muscle, skeletal, receptor tyrosine kinase
MVP major vault protein
MYD88 myeloid differentiation primary response 88
MYH10 myosin, heavy chain 10, non-muscle
MYH11 myosin, heavy chain 11, smooth muscle
MYH14 myosin, heavy chain 14, non-muscle
MYH9 myosin, heavy chain 9, non-muscle
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
MYL12B myosin, light chain 12B, regulatory
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle
MYL9 myosin, light chain 9, regulatory
MYO1C myosin IC
MYO1E myosin IE
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
NAMPT nicotinamide phosphoribosyltransferase
NCF1 neutrophil cytosolic factor 1
NCF2 neutrophil cytosolic factor 2
NCF4 neutrophil cytosolic factor 4, 40kDa
NCK1 NCK adaptor protein 1
NCK2 NCK adaptor protein 2
NCKAP1 NCK-associated protein 1
NCSTN nicastrin
NDN necdin, melanoma antigen (MAGE) family member
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
NET1 neuroepithelial cell transforming 1
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NGEF neuronal guanine nucleotide exchange factor
NGF nerve growth factor (beta polypeptide)
NGFR nerve growth factor receptor
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
NOG noggin
NOS3 nitric oxide synthase 3 (endothelial cell)
NPTN neuroplastin
NR4A1 nuclear receptor subfamily 4, group A, member 1
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NRG1 neuregulin 1
NRG2 neuregulin 2
NRG4 neuregulin 4
NRP1 neuropilin 1
NRP2 neuropilin 2
NRTN neurturin
NTF3 neurotrophin 3
NTF4 neurotrophin 4
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
OMG oligodendrocyte myelin glycoprotein
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PCSK5 proprotein convertase subtilisin/kexin type 5
PCSK6 proprotein convertase subtilisin/kexin type 6
PDCD6 programmed cell death 6
PDE1A phosphodiesterase 1A, calmodulin-dependent
PDE1B phosphodiesterase 1B, calmodulin-dependent
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa
PDE3B phosphodiesterase 3B, cGMP-inhibited
PDGFA platelet-derived growth factor alpha polypeptide
PDGFB platelet-derived growth factor beta polypeptide
PDGFC platelet derived growth factor C
PDGFD platelet derived growth factor D
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDGFRL platelet-derived growth factor receptor-like
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PDPK1 3-phosphoinositide dependent protein kinase 1
PGF placental growth factor
PHIP pleckstrin homology domain interacting protein
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2
PIGR polymeric immunoglobulin receptor
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4
PILRB paired immunoglobin-like type 2 receptor beta
PLAT plasminogen activator, tissue
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLCE1 phospholipase C, epsilon 1
PLCG1 phospholipase C, gamma 1
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
PLEKHG2 pleckstrin homology domain containing, family G (with RhoGef domain) member 2
PLEKHG5 pleckstrin homology domain containing, family G (with RhoGef domain) member 5
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PPP2R5D protein phosphatase 2, regulatory subunit B', delta
PRDM4 PR domain containing 4
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PRKAG3 protein kinase, AMP-activated, gamma 3 non-catalytic subunit
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRKCA protein kinase C, alpha
PRKCB protein kinase C, beta
PRKCD protein kinase C, delta
PRKCE protein kinase C, epsilon
PRKCG protein kinase C, gamma
PRKCI protein kinase C, iota
PRKCZ protein kinase C, zeta
PRKD1 protein kinase D1
PRKD2 protein kinase D2
PSEN2 presenilin 2
PSENEN presenilin enhancer gamma secretase subunit
PTEN phosphatase and tensin homolog
PTK2 protein tyrosine kinase 2
PTK2B protein tyrosine kinase 2 beta
PTK6 protein tyrosine kinase 6
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PTPRA protein tyrosine phosphatase, receptor type, A
PTPRG protein tyrosine phosphatase, receptor type, G
PTPRJ protein tyrosine phosphatase, receptor type, J
PTPRR protein tyrosine phosphatase, receptor type, R
PTPRT protein tyrosine phosphatase, receptor type, T
PXN paxillin
RAB14 RAB14, member RAS oncogene family
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RALA v-ral simian leukemia viral oncogene homolog A (ras related)
RALB v-ral simian leukemia viral oncogene homolog B
RALGDS ral guanine nucleotide dissociation stimulator
RAP1A RAP1A, member of RAS oncogene family
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RASA1 RAS p21 protein activator (GTPase activating protein) 1
RASGRF2 Ras protein-specific guanine nucleotide-releasing factor 2
RASGRP4 RAS guanyl releasing protein 4
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
REPS2 RALBP1 associated Eps domain containing 2
RET ret proto-oncogene
RGS14 regulator of G-protein signaling 14
RHEB Ras homolog enriched in brain
RHOA ras homolog family member A
RHOQ ras homolog family member Q
RICTOR RPTOR independent companion of MTOR, complex 2
RIPK2 receptor-interacting serine-threonine kinase 2
RIT1 Ras-like without CAAX 1
RIT2 Ras-like without CAAX 2
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
ROR1 receptor tyrosine kinase-like orphan receptor 1
ROR2 receptor tyrosine kinase-like orphan receptor 2
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase
RPE65 retinal pigment epithelium-specific protein 65kDa
RPS27A ribosomal protein S27a
RPS6 ribosomal protein S6
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2
RPTOR regulatory associated protein of MTOR, complex 1
RTN4 reticulon 4
RTN4R reticulon 4 receptor
SDC2 syndecan 2
SDCBP syndecan binding protein (syntenin)
SETX senataxin
SGPL1 sphingosine-1-phosphate lyase 1
SH2B2 SH2B adaptor protein 2
SH2D2A SH2 domain containing 2A
SH3GL2 SH3-domain GRB2-like 2
SH3KBP1 SH3-domain kinase binding protein 1
SHB Src homology 2 domain containing adaptor protein B
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SHC2 SHC (Src homology 2 domain containing) transforming protein 2
SHC3 SHC (Src homology 2 domain containing) transforming protein 3
SHC4 SHC (Src homology 2 domain containing) family, member 4
SHCBP1 SHC SH2-domain binding protein 1
SHOC2 soc-2 suppressor of clear homolog (C. elegans)
SIK2 salt-inducible kinase 2
SIPA1L1 signal-induced proliferation-associated 1 like 1
SIRT2 sirtuin 2
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC9A6 solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SOCS2 suppressor of cytokine signaling 2
SOCS5 suppressor of cytokine signaling 5
SOCS7 suppressor of cytokine signaling 7
SOGA1 suppressor of glucose, autophagy associated 1
SORBS1 sorbin and SH3 domain containing 1
SORT1 sortilin 1
SOS1 son of sevenless homolog 1 (Drosophila)
SOS2 son of sevenless homolog 2 (Drosophila)
SOX9 SRY (sex determining region Y)-box 9
SPHK1 sphingosine kinase 1
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SPRY2 sprouty homolog 2 (Drosophila)
SQSTM1 sequestosome 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SREBF1 sterol regulatory element binding transcription factor 1
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites
SS18 synovial sarcoma translocation, chromosome 18
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
STAP1 signal transducing adaptor family member 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STK11 serine/threonine kinase 11
STRADA STE20-related kinase adaptor alpha
STRADB STE20-related kinase adaptor beta
STXBP4 syntaxin binding protein 4
STYK1 serine/threonine/tyrosine kinase 1
SULF1 sulfatase 1
SULF2 sulfatase 2
SYK spleen tyrosine kinase
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
TDGF1 teratocarcinoma-derived growth factor 1
TEC tec protein tyrosine kinase
TEK TEK tyrosine kinase, endothelial
TGFA transforming growth factor, alpha
TGFB1 transforming growth factor, beta 1
THEM4 thioesterase superfamily member 4
TIAM1 T-cell lymphoma invasion and metastasis 1
TIAM2 T-cell lymphoma invasion and metastasis 2
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TLR9 toll-like receptor 9
TNK1 tyrosine kinase, non-receptor, 1
TNK2 tyrosine kinase, non-receptor, 2
TNRC6A trinucleotide repeat containing 6A
TNRC6B trinucleotide repeat containing 6B
TNRC6C trinucleotide repeat containing 6C
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRAT1 T cell receptor associated transmembrane adaptor 1
TRIB3 tribbles pseudokinase 3
TRIM71 tripartite motif containing 71, E3 ubiquitin protein ligase
TRIO trio Rho guanine nucleotide exchange factor
TSC1 tuberous sclerosis 1
TSC2 tuberous sclerosis 2
TXK TXK tyrosine kinase
TXNIP thioredoxin interacting protein
TYK2 tyrosine kinase 2
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBB ubiquitin B
UBC ubiquitin C
VAV1 vav 1 guanine nucleotide exchange factor
VAV2 vav 2 guanine nucleotide exchange factor
VAV3 vav 3 guanine nucleotide exchange factor
VEGFA vascular endothelial growth factor A
VEGFB vascular endothelial growth factor B
VEGFC vascular endothelial growth factor C
VIL1 villin 1
WASF2 WAS protein family, member 2
WASL Wiskott-Aldrich syndrome-like
YES1 YES proto-oncogene 1, Src family tyrosine kinase
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZFAND5 zinc finger, AN1-type domain 5
ZFYVE27 zinc finger, FYVE domain containing 27
ZNF106 zinc finger protein 106