transmembrane receptor protein serine/threonine kinase signaling pathway Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell where the receptor possesses serine/threonine kinase activity, and ending with regulation of a downstream cellular process, e.g. transcription. (Gene Ontology, GO_0007178)
External Link http://amigo.geneontology.org/amigo/term/GO:0007178
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Genes

199 genes participating in the transmembrane receptor protein serine/threonine kinase signaling pathway biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ACVR1 activin A receptor, type I
ACVR1B activin A receptor, type IB
ACVR1C activin A receptor, type IC
ACVR2A activin A receptor, type IIA
ACVR2B activin A receptor, type IIB
ACVRL1 activin A receptor type II-like 1
ADAM9 ADAM metallopeptidase domain 9
AKAP3 A kinase (PRKA) anchor protein 3
AKAP4 A kinase (PRKA) anchor protein 4
AMHR2 anti-Mullerian hormone receptor, type II
APOA1 apolipoprotein A-I
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18
ARRB2 arrestin, beta 2
BAMBI BMP and activin membrane-bound inhibitor
BMP10 bone morphogenetic protein 10
BMP15 bone morphogenetic protein 15
BMP2 bone morphogenetic protein 2
BMP4 bone morphogenetic protein 4
BMP5 bone morphogenetic protein 5
BMP6 bone morphogenetic protein 6
BMP7 bone morphogenetic protein 7
BMP8A bone morphogenetic protein 8a
BMP8B bone morphogenetic protein 8b
BMPR1A bone morphogenetic protein receptor, type IA
BMPR1B bone morphogenetic protein receptor, type IB
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
C10ORF54 chromosome 10 open reading frame 54
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCL2 chemokine (C-C motif) ligand 2
CCNC cyclin C
CCNT1 cyclin T1
CCNT2 cyclin T2
CDK8 cyclin-dependent kinase 8
CDK9 cyclin-dependent kinase 9
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CER1 cerberus 1, DAN family BMP antagonist
CFC1 cripto, FRL-1, cryptic family 1
CGN cingulin
CHRD chordin
CHRDL1 chordin-like 1
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
COL1A2 collagen, type I, alpha 2
COL3A1 collagen, type III, alpha 1
DLX5 distal-less homeobox 5
DSG4 desmoglein 4
DUSP15 dual specificity phosphatase 15
DUSP22 dual specificity phosphatase 22
E2F4 E2F transcription factor 4, p107/p130-binding
E2F5 E2F transcription factor 5, p130-binding
ECSIT ECSIT signalling integrator
EGR1 early growth response 1
ENG endoglin
ETV2 ets variant 2
F11R F11 receptor
FAM83G family with sequence similarity 83, member G
FERMT2 fermitin family member 2
FGF8 fibroblast growth factor 8 (androgen-induced)
FKBP1A FK506 binding protein 1A, 12kDa
FNTA farnesyltransferase, CAAX box, alpha
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXH1 forkhead box H1
FSHB follicle stimulating hormone, beta polypeptide
FST follistatin
FSTL1 follistatin-like 1
FURIN furin (paired basic amino acid cleaving enzyme)
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
GATA4 GATA binding protein 4
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GDF1 growth differentiation factor 1
GDF10 growth differentiation factor 10
GDF15 growth differentiation factor 15
GDF2 growth differentiation factor 2
GDF5 growth differentiation factor 5
GDF6 growth differentiation factor 6
GDF7 growth differentiation factor 7
GDF9 growth differentiation factor 9
GREM2 gremlin 2, DAN family BMP antagonist
HDAC1 histone deacetylase 1
HFE hemochromatosis
HFE2 hemochromatosis type 2 (juvenile)
HIPK2 homeodomain interacting protein kinase 2
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
INHBA inhibin, beta A
INHBB inhibin, beta B
IRAK1 interleukin-1 receptor-associated kinase 1
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB5 integrin, beta 5
JUN jun proto-oncogene
JUNB jun B proto-oncogene
KLF10 Kruppel-like factor 10
LEF1 lymphoid enhancer-binding factor 1
LEFTY1 left-right determination factor 1
LEFTY2 left-right determination factor 2
LTBP1 latent transforming growth factor beta binding protein 1
LTBP2 latent transforming growth factor beta binding protein 2
LTBP3 latent transforming growth factor beta binding protein 3
LTBP4 latent transforming growth factor beta binding protein 4
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MEGF8 multiple EGF-like-domains 8
MEN1 multiple endocrine neoplasia I
MSTN myostatin
MSX1 msh homeobox 1
MSX2 msh homeobox 2
MTMR4 myotubularin related protein 4
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYH6 myosin, heavy chain 6, cardiac muscle, alpha
NCOR1 nuclear receptor corepressor 1
NCOR2 nuclear receptor corepressor 2
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NEDD8 neural precursor cell expressed, developmentally down-regulated 8
NKX2-5 NK2 homeobox 5
NLK nemo-like kinase
NODAL nodal growth differentiation factor
NOG noggin
PARD3 par-3 family cell polarity regulator
PARD6A par-6 family cell polarity regulator alpha
PARP1 poly (ADP-ribose) polymerase 1
PDGFA platelet-derived growth factor alpha polypeptide
PDGFB platelet-derived growth factor beta polypeptide
PMEPA1 prostate transmembrane protein, androgen induced 1
PML promyelocytic leukemia
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A
PPM1L protein phosphatase, Mg2+/Mn2+ dependent, 1L
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PRKCZ protein kinase C, zeta
PTK2 protein tyrosine kinase 2
PTPRK protein tyrosine phosphatase, receptor type, K
PXN paxillin
RBL1 retinoblastoma-like 1
RGMA repulsive guidance molecule family member a
RGMB repulsive guidance molecule family member b
RHOA ras homolog family member A
RNF111 ring finger protein 111
RPS27A ribosomal protein S27a
RUNX2 runt-related transcription factor 2
RYR2 ryanodine receptor 2 (cardiac)
SCX scleraxis basic helix-loop-helix transcription factor
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SKI SKI proto-oncogene
SKIL SKI-like proto-oncogene
SLC39A5 solute carrier family 39 (zinc transporter), member 5
SMAD1 SMAD family member 1
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SMAD4 SMAD family member 4
SMAD5 SMAD family member 5
SMAD6 SMAD family member 6
SMAD7 SMAD family member 7
SMAD9 SMAD family member 9
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SMURF2 SMAD specific E3 ubiquitin protein ligase 2
SP1 Sp1 transcription factor
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STRAP serine/threonine kinase receptor associated protein
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
T T, brachyury homolog (mouse)
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TDGF1 teratocarcinoma-derived growth factor 1
TFDP1 transcription factor Dp-1
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2)
TGFB1 transforming growth factor, beta 1
TGFB2 transforming growth factor, beta 2
TGFB3 transforming growth factor, beta 3
TGFBR1 transforming growth factor, beta receptor 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TGFBR3 transforming growth factor, beta receptor III
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TGIF1 TGFB-induced factor homeobox 1
TMEM100 transmembrane protein 100
TP53 tumor protein p53
TRIM33 tripartite motif containing 33
TRPS1 trichorhinophalangeal syndrome I
TWSG1 twisted gastrulation BMP signaling modulator 1
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBB ubiquitin B
UBC ubiquitin C
UBE2D1 ubiquitin-conjugating enzyme E2D 1
UBE2D3 ubiquitin-conjugating enzyme E2D 3
UBE2M ubiquitin-conjugating enzyme E2M
UCHL5 ubiquitin carboxyl-terminal hydrolase L5
USP15 ubiquitin specific peptidase 15
USP9X ubiquitin specific peptidase 9, X-linked
USP9Y ubiquitin specific peptidase 9, Y-linked
WFIKKN2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
WWTR1 WW domain containing transcription regulator 1
XPO1 exportin 1
ZCCHC12 zinc finger, CCHC domain containing 12
ZFYVE16 zinc finger, FYVE domain containing 16
ZFYVE9 zinc finger, FYVE domain containing 9
ZNF8 zinc finger protein 8
ZYX zyxin