translesion synthesis Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description The replication of damaged DNA by synthesis across a lesion in the template strand; a specialized DNA polymerase or replication complex inserts a defined nucleotide across from the lesion which allows DNA synthesis to continue beyond the lesion. This process can be mutagenic depending on the damaged nucleotide and the inserted nucleotide. (Gene Ontology, GO_0019985)
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12 genes participating in the translesion synthesis biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
C1ORF86 chromosome 1 open reading frame 86
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
KIAA0101 KIAA0101
KIAA2022 KIAA2022
PCNA proliferating cell nuclear antigen
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
POLN polymerase (DNA directed) nu
PRIMPOL primase and polymerase (DNA-directed)
REV1 REV1, polymerase (DNA directed)
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit
SPRTN SprT-like N-terminal domain
VCP valosin containing protein