transitional cell carcinoma Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A carcinoma that derives_from transitional epithelial cells. (Human Disease Ontology, DOID_2671)
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Genes

237 genes co-occuring with the disease transitional cell carcinoma in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
ZNF135 zinc finger protein 135 2.02114
TP53 tumor protein p53 1.9577
UPK2 uroplakin 2 1.59564
KRT20 keratin 20, type I 1.5238
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 1.51325
PCNA proliferating cell nuclear antigen 1.30052
SERTAD3 SERTA domain containing 3 1.27868
UPK1B uroplakin 1B 1.22258
ERBB2 erb-b2 receptor tyrosine kinase 2 1.21305
CNTN2 contactin 2 (axonal) 1.1841
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.16179
ZNF77 zinc finger protein 77 1.1507
KRT7 keratin 7, type II 1.13628
UPK3A uroplakin 3A 1.13416
IFNA2 interferon, alpha 2 1.12319
UPK1A uroplakin 1A 1.11183
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.07992
EGFR epidermal growth factor receptor 1.04083
BIRC5 baculoviral IAP repeat containing 5 0.960797
HPD 4-hydroxyphenylpyruvate dioxygenase 0.960378
TICAM2 toll-like receptor adaptor molecule 2 0.897051
ENO2 enolase 2 (gamma, neuronal) 0.892948
CDKN2A cyclin-dependent kinase inhibitor 2A 0.887618
IL2 interleukin 2 0.883111
LRRN4 leucine rich repeat neuronal 4 0.872462
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 0.862637
HEPACAM hepatic and glial cell adhesion molecule 0.831099
DAPK1 death-associated protein kinase 1 0.822077
GSTP1 glutathione S-transferase pi 1 0.803205
MKI67 marker of proliferation Ki-67 0.798692
GSTM1 glutathione S-transferase mu 1 0.787623
FN1 fibronectin 1 0.782707
PRRC2C proline-rich coiled-coil 2C 0.760639
IFNA1 interferon, alpha 1 0.759008
HRAS Harvey rat sarcoma viral oncogene homolog 0.753306
MSH2 mutS homolog 2 0.745578
KLK3 kallikrein-related peptidase 3 0.717635
CCND1 cyclin D1 0.705144
ACPP acid phosphatase, prostate 0.703536
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.699517
SYP synaptophysin 0.687491
FGFR3 fibroblast growth factor receptor 3 0.683093
MMP9 matrix metallopeptidase 9 0.677504
CD44 CD44 molecule (Indian blood group) 0.659215
KRT8 keratin 8, type II 0.658818
NLRP8 NLR family, pyrin domain containing 8 0.656837
RAB26 RAB26, member RAS oncogene family 0.648533
GSTA1 glutathione S-transferase alpha 1 0.648533
UPK3B uroplakin 3B 0.644981
GSTT1 glutathione S-transferase theta 1 0.642615
GSTTP1 glutathione S-transferase theta pseudogene 1 0.642615
PLAU plasminogen activator, urokinase 0.635921
FGF2 fibroblast growth factor 2 (basic) 0.625711
GSTA3 glutathione S-transferase alpha 3 0.61866
GSTA2 glutathione S-transferase alpha 2 0.617094
GSTA4 glutathione S-transferase alpha 4 0.615921
ZNF189 zinc finger protein 189 0.606543
CD226 CD226 molecule 0.60069
LZTS1 leucine zipper, putative tumor suppressor 1 0.59991
MAGEA8 melanoma antigen family A8 0.593285
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 0.576939
PSCA prostate stem cell antigen 0.576161
KRTAP11-1 keratin associated protein 11-1 0.575772
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase 0.573828
HBA2 hemoglobin, alpha 2 0.56722
STK10 serine/threonine kinase 10 0.562169
HBA1 hemoglobin, alpha 1 0.555956
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 0.545093
MMP2 matrix metallopeptidase 2 0.541605
FHIT fragile histidine triad 0.540055
MLH1 mutL homolog 1 0.534248
DNTT DNA nucleotidylexotransferase 0.528063
KRT5 keratin 5, type II 0.526904
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3 0.505356
OTOA otoancorin 0.500761
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 0.493885
PTHLH parathyroid hormone-like hormone 0.491215
HMBS hydroxymethylbilane synthase 0.487407
KRT34 keratin 34, type I 0.484744
GSTM3 glutathione S-transferase mu 3 (brain) 0.484364
APP amyloid beta (A4) precursor protein 0.474498
KRT19 keratin 19, type I 0.466172
ANKRD6 ankyrin repeat domain 6 0.463905
NEU2 sialidase 2 (cytosolic sialidase) 0.461639
BCL2 B-cell CLL/lymphoma 2 0.458619
TYMP thymidine phosphorylase 0.458241
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.456355
ELAVL3 ELAV like neuron-specific RNA binding protein 3 0.451831
THBD thrombomodulin 0.447311
CHD6 chromodomain helicase DNA binding protein 6 0.446182
FAXDC2 fatty acid hydroxylase domain containing 2 0.445052
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.442418
C3ORF18 chromosome 3 open reading frame 18 0.44129
IGLV5-52 immunoglobulin lambda variable 5-52 0.438282
ERBB3 erb-b2 receptor tyrosine kinase 3 0.43753
CTSD cathepsin D 0.430393
PDPN podoplanin 0.425514
KRT14 keratin 14, type I 0.42214
DACT1 dishevelled-binding antagonist of beta-catenin 1 0.421016
DAP death-associated protein 0.418019
NLRP10 NLR family, pyrin domain containing 10 0.418019
RASSF6 Ras association (RalGDS/AF-6) domain family member 6 0.416147
APAF1 apoptotic peptidase activating factor 1 0.415024
CSH1 chorionic somatomammotropin hormone 1 (placental lactogen) 0.415024
PIDD1 p53-induced death domain protein 1 0.410909
TERT telomerase reverse transcriptase 0.410535
CTSB cathepsin B 0.404931
CXCL8 chemokine (C-X-C motif) ligand 8 0.403438
SERTAD1 SERTA domain containing 1 0.401945
BAX BCL2-associated X protein 0.395235
CSH2 chorionic somatomammotropin hormone 2 0.394863
CHGA chromogranin A 0.392629
ALPPL2 alkaline phosphatase, placental-like 2 0.391885
ALPP alkaline phosphatase, placental 0.391141
ALPL alkaline phosphatase, liver/bone/kidney 0.390769
PRB2 proline-rich protein BstNI subfamily 2 0.388538
EIF3A eukaryotic translation initiation factor 3, subunit A 0.385936
POLK polymerase (DNA directed) kappa 0.384079
TGFB1 transforming growth factor, beta 1 0.383337
KRT13 keratin 13, type I 0.378514
HBEGF heparin-binding EGF-like growth factor 0.378143
NFU1 NFU1 iron-sulfur cluster scaffold 0.377773
ANXA5 annexin A5 0.37629
NUMA1 nuclear mitotic apparatus protein 1 0.372958
CD68 CD68 molecule 0.371847
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase 0.368888
ANKRD11 ankyrin repeat domain 11 0.368518
SAT1 spermidine/spermine N1-acetyltransferase 1 0.363347
CTAGE1 cutaneous T-cell lymphoma-associated antigen 1 0.36187
LIPI lipase, member I 0.343106
ACRBP acrosin binding protein 0.343106
IFNA21 interferon, alpha 21 0.339806
MIB1 mindbomb E3 ubiquitin protein ligase 1 0.336144
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 0.331025
TIMP2 TIMP metallopeptidase inhibitor 2 0.33066
KRT18 keratin 18, type I 0.328834
CD27 CD27 molecule 0.328469
SRL sarcalumenin 0.326646
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 0.32009
CAPG capping protein (actin filament), gelsolin-like 0.319726
IFNA17 interferon, alpha 17 0.318999
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.317909
BSG basigin (Ok blood group) 0.315366
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase) 0.313552
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 0.311739
RASSF3 Ras association (RalGDS/AF-6) domain family member 3 0.30848
SOX4 SRY (sex determining region Y)-box 4 0.307395
CA9 carbonic anhydrase IX 0.300894
ERBB4 erb-b2 receptor tyrosine kinase 4 0.299812
MAGEA12 melanoma antigen family A12 0.296211
RACGAP1 Rac GTPase activating protein 1 0.295492
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.291539
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 0.289744
NCAM1 neural cell adhesion molecule 1 0.27794
PTGES prostaglandin E synthase 0.277227
AR androgen receptor 0.275445
PAX2 paired box 2 0.274376
OPLAH 5-oxoprolinase (ATP-hydrolysing) 0.269753
MVP major vault protein 0.268332
DMBT1 deleted in malignant brain tumors 1 0.266558
RYK receptor-like tyrosine kinase 0.265849
MINA MYC induced nuclear antigen 0.263722
NLRP2 NLR family, pyrin domain containing 2 0.263368
GPI glucose-6-phosphate isomerase 0.263368
DNMT1 DNA (cytosine-5-)-methyltransferase 1 0.263014
SPINK1 serine peptidase inhibitor, Kazal type 1 0.260184
MT1E metallothionein 1E 0.25877
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1 0.258417
MSLN mesothelin 0.258064
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae) 0.257358
IL3 interleukin 3 0.250663
TRPM5 transient receptor potential cation channel, subfamily M, member 5 0.247852
ADD2 adducin 2 (beta) 0.247852
GSTM2 glutathione S-transferase mu 2 (muscle) 0.245747
CSF3 colony stimulating factor 3 (granulocyte) 0.245046
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 0.244696
WT1 Wilms tumor 1 0.244345
PTEN phosphatase and tensin homolog 0.242945
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.242245
PNN pinin, desmosome associated protein 0.240148
PLG plasminogen 0.238403
PAX5 paired box 5 0.237009
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) 0.234573
ODC1 ornithine decarboxylase 1 0.229716
MCM2 minichromosome maintenance complex component 2 0.228679
MZF1 myeloid zinc finger 1 0.222479
FAM195A family with sequence similarity 195, member A 0.221793
PTTG1 pituitary tumor-transforming 1 0.220424
CSF1R colony stimulating factor 1 receptor 0.218374
IL7R interleukin 7 receptor 0.212271
AFP alpha-fetoprotein 0.209248
EP400 E1A binding protein p400 0.207912
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.205585
TBXAS1 thromboxane A synthase 1 (platelet) 0.203604
MSH6 mutS homolog 6 0.202946
VEGFA vascular endothelial growth factor A 0.201308
TRAF3 TNF receptor-associated factor 3 0.200982
DLK1 delta-like 1 homolog (Drosophila) 0.200982
CD4 CD4 molecule 0.200656
TIMP1 TIMP metallopeptidase inhibitor 1 0.199356
PCDH10 protocadherin 10 0.198064
REEP5 receptor accessory protein 5 0.198064
CFH complement factor H 0.195183
HOXC6 homeobox C6 0.195183
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.193915
B3GAT1 beta-1,3-glucuronyltransferase 1 0.192657
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 0.188632
ERV3-1 endogenous retrovirus group 3, member 1 0.188022
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 0.186811
IGLV9-49 immunoglobulin lambda variable 9-49 0.185612
DNA2 DNA replication helicase/nuclease 2 0.181798
RB1 retinoblastoma 1 0.18151
ICAM1 intercellular adhesion molecule 1 0.180084
CD1A CD1a molecule 0.17952
MMP1 matrix metallopeptidase 1 0.175679
F8 coagulation factor VIII, procoagulant component 0.174881
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 0.174881
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.174617
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.170789
HLA-A major histocompatibility complex, class I, A 0.170544
STAG2 stromal antigen 2 0.169812
NBPF10 neuroblastoma breakpoint family, member 10 0.166995
CD6 CD6 molecule 0.165655
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1 0.165435
KERA keratocan 0.164359
PTGES2 prostaglandin E synthase 2 0.162707
TMEM245 transmembrane protein 245 0.162109
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 0.161716
ACTB actin, beta 0.161139
PTER phosphotriesterase related 0.160761
MT1G metallothionein 1G 0.160203
STIL SCL/TAL1 interrupting locus 0.159302
SLC46A1 solute carrier family 46 (folate transporter), member 1 0.158434
DCXR dicarbonyl/L-xylulose reductase 0.143255
LYZ lysozyme 0.141453
LTA lymphotoxin alpha 0.141055
IGF2 insulin-like growth factor 2 0.135529