transforming growth factor beta activated kinase 1 complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A protein complex that possesses protein kinase activity and activates the I-kappa B kinase complex (IKK) and mitogen-activated protein (MAP) kinases in response to TRAF6 signaling. It comprises the catalytic subunit TAK1 complexed to the regulatory subunits, termed TABs (TAK1-binding subunits). (Gene Ontology, GO_0097076)
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45 proteins co-occuring with the transforming growth factor beta activated kinase 1 complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 1.95583
MAP3K7 mitogen-activated protein kinase kinase kinase 7 1.74383
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 1.57302
TIFA TRAF-interacting protein with forkhead-associated domain 1.39851
RIPK3 receptor-interacting serine-threonine kinase 3 1.07917
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase 0.881016
TRIM5 tripartite motif containing 5 0.869966
SKAP1 src kinase associated phosphoprotein 1 0.802021
WISP3 WNT1 inducible signaling pathway protein 3 0.79927
USP4 ubiquitin specific peptidase 4 (proto-oncogene) 0.689888
CYLD cylindromatosis (turban tumor syndrome) 0.675065
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.609086
UBE2V2 ubiquitin-conjugating enzyme E2 variant 2 0.599381
ITCH itchy E3 ubiquitin protein ligase 0.58678
SOX5 SRY (sex determining region Y)-box 5 0.555559
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 0.540294
FYB FYN binding protein 0.53906
SOX6 SRY (sex determining region Y)-box 6 0.519798
TNF tumor necrosis factor 0.516124
UBE2N ubiquitin-conjugating enzyme E2N 0.507163
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.476831
SMAD7 SMAD family member 7 0.460401
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 0.444085
MAPK14 mitogen-activated protein kinase 14 0.427497
SMAD6 SMAD family member 6 0.417294
MAP2K3 mitogen-activated protein kinase kinase 3 0.413382
ATF2 activating transcription factor 2 0.404804
MALT1 MALT1 paracaspase 0.401693
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 0.383509
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 0.340017
BCL10 B-cell CLL/lymphoma 10 0.329084
CNTN2 contactin 2 (axonal) 0.320826
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.286245
WNT1 wingless-type MMTV integration site family, member 1 0.281085
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.281085
TGFB1 transforming growth factor, beta 1 0.26312
BMP2 bone morphogenetic protein 2 0.256197
BIRC2 baculoviral IAP repeat containing 2 0.256197
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.221025
RFC2 replication factor C (activator 1) 2, 40kDa 0.215761
BIRC3 baculoviral IAP repeat containing 3 0.215412
PARK2 parkin RBR E3 ubiquitin protein ligase 0.210203
CASP7 caspase 7, apoptosis-related cysteine peptidase 0.208137
COL2A1 collagen, type II, alpha 1 0.185469
JUN jun proto-oncogene 0.178588