transcription elongation factor complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description Any protein complex that interacts with RNA polymerase II to increase (positive transcription elongation factor) or reduce (negative transcription elongation factor) the rate of transcription elongation. (Gene Ontology, GO_0008023)
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Genes

315 proteins co-occuring with the transcription elongation factor complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
CDK9 cyclin-dependent kinase 9 3.2616
CCNT1 cyclin T1 3.03075
HEXIM1 hexamethylene bis-acetamide inducible 1 2.55479
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor 2.26511
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae) 2.08016
RTF1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) 1.90424
BRD4 bromodomain containing 4 1.89385
CUL5 cullin 5 1.79442
TCEB2 transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B) 1.79243
TCEB3 transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A) 1.77339
TAT tyrosine aminotransferase 1.77275
SUPT4H1 suppressor of Ty 4 homolog 1 (S. cerevisiae) 1.76238
CTR9 CTR9, Paf1/RNA polymerase II complex component 1.73561
CDC73 cell division cycle 73 1.68848
CUL2 cullin 2 1.67994
LEO1 Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) 1.62472
TCEB1 transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) 1.62
AFF4 AF4/FMR2 family, member 4 1.58852
CCNT2 cyclin T2 1.58622
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase 1.56219
LARP7 La ribonucleoprotein domain family, member 7 1.56162
HEXIM2 hexamethylene bis-acetamide inducible 2 1.51694
CCNK cyclin K 1.50735
JAG2 jagged 2 1.48136
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae) 1.46269
ELL elongation factor RNA polymerase II 1.46043
RBX1 ring-box 1, E3 ubiquitin protein ligase 1.45194
SSRP1 structure specific recognition protein 1 1.44121
CDK7 cyclin-dependent kinase 7 1.38128
NELFB negative elongation factor complex member B 1.36747
NELFA negative elongation factor complex member A 1.2905
ELL2 elongation factor, RNA polymerase II, 2 1.24236
MEPCE methylphosphate capping enzyme 1.2086
H3F3A H3 histone, family 3A 1.18697
H3F3B H3 histone, family 3B (H3.3B) 1.18697
HIST2H3PS2 histone cluster 2, H3, pseudogene 2 1.16901
HIST2H2BF histone cluster 2, H2bf 1.14443
HIST1H2BD histone cluster 1, H2bd 1.14443
HIST3H2BB histone cluster 3, H2bb 1.14443
HIST1H2BH histone cluster 1, H2bh 1.14443
HIST1H2BF histone cluster 1, H2bf 1.14239
HIST1H2BC histone cluster 1, H2bc 1.14239
HIST1H2BA histone cluster 1, H2ba 1.14085
CISH cytokine inducible SH2-containing protein 1.11276
AFF1 AF4/FMR2 family, member 1 1.09391
MLLT1 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 1.07816
PARK2 parkin RBR E3 ubiquitin protein ligase 1.05387
SETD2 SET domain containing 2 0.941636
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa 0.858933
TCEA1 transcription elongation factor A (SII), 1 0.855257
SETD1A SET domain containing 1A 0.851583
MED26 mediator complex subunit 26 0.841023
PCF11 PCF11 cleavage and polyadenylation factor subunit 0.833679
TCEA2 transcription elongation factor A (SII), 2 0.830466
AFF3 AF4/FMR2 family, member 3 0.804313
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2) 0.798353
TAF7 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa 0.793313
GTF2B general transcription factor IIB 0.789649
ZNF512 zinc finger protein 512 0.784156
LRRC41 leucine rich repeat containing 41 0.780954
CHD1 chromodomain helicase DNA binding protein 1 0.759069
SSU72 SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae) 0.758161
VBP1 von Hippel-Lindau binding protein 1 0.75317
SKP1 S-phase kinase-associated protein 1 0.740965
CDK8 cyclin-dependent kinase 8 0.738263
BRD2 bromodomain containing 2 0.680719
NELFE negative elongation factor complex member E 0.662935
RNGTT RNA guanylyltransferase and 5'-phosphatase 0.652159
SOCS3 suppressor of cytokine signaling 3 0.638434
CEP85 centrosomal protein 85kDa 0.629892
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa 0.625632
ASB6 ankyrin repeat and SOCS box containing 6 0.623504
DOT1L DOT1-like histone H3K79 methyltransferase 0.623079
TCEANC transcription elongation factor A (SII) N-terminal and central domain containing 0.620954
REXO1 REX1, RNA exonuclease 1 homolog (S. cerevisiae) 0.615013
CDK12 cyclin-dependent kinase 12 0.612048
KAT2B K(lysine) acetyltransferase 2B 0.597697
GLTSCR1 glioma tumor suppressor candidate region gene 1 0.595593
ASB11 ankyrin repeat and SOCS box containing 11, E3 ubiquitin protein ligase 0.589714
RNF20 ring finger protein 20, E3 ubiquitin protein ligase 0.585942
SOCS6 suppressor of cytokine signaling 6 0.571745
WSB1 WD repeat and SOCS box containing 1 0.560943
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 0.558457
TCEB3C transcription elongation factor B polypeptide 3C (elongin A3) 0.548947
FBXO40 F-box protein 40 0.546885
CIITA class II, major histocompatibility complex, transactivator 0.54606
SNW1 SNW domain containing 1 0.545648
HSPA4 heat shock 70kDa protein 4 0.539883
HMGA1 high mobility group AT-hook 1 0.521432
PPP1R10P1 protein phosphatase 1, regulatory subunit 10 pseudogene 1 0.509604
ASB1 ankyrin repeat and SOCS box containing 1 0.502693
CD4 CD4 molecule 0.501881
TP53 tumor protein p53 0.500258
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein) 0.490539
AFF2 AF4/FMR2 family, member 2 0.474018
KTI12 KTI12 homolog, chromatin associated (S. cerevisiae) 0.474018
ELL3 elongation factor RNA polymerase II-like 3 0.459602
TBP TATA box binding protein 0.448848
SOCS2 suppressor of cytokine signaling 2 0.446465
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A 0.434591
H2AFB2 H2A histone family, member B2 0.433801
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G 0.424353
KIAA0101 KIAA0101 0.410259
COMMD1 copper metabolism (Murr1) domain containing 1 0.409869
HIST1H4C histone cluster 1, H4c 0.408309
HIST2H4B histone cluster 2, H4b 0.408309
HIST2H4A histone cluster 2, H4a 0.408309
HIST1H4F histone cluster 1, H4f 0.408309
HIST1H4B histone cluster 1, H4b 0.408309
HIST1H4I histone cluster 1, H4i 0.408309
HIST1H4H histone cluster 1, H4h 0.408309
HIST1H4D histone cluster 1, H4d 0.408309
HIST1H4E histone cluster 1, H4e 0.408309
HIST1H4K histone cluster 1, H4k 0.408309
HIST1H4A histone cluster 1, H4a 0.408309
HIST1H4J histone cluster 1, H4j 0.408309
HIST4H4 histone cluster 4, H4 0.407919
HIST1H4L histone cluster 1, H4l 0.407919
CDC34 cell division cycle 34 0.405193
SOCS1 suppressor of cytokine signaling 1 0.400527
LMO2 LIM domain only 2 (rhombotin-like 1) 0.397811
CUL1 cullin 1 0.391615
ASB9 ankyrin repeat and SOCS box containing 9 0.390455
INTS6 integrator complex subunit 6 0.390068
JAK2 Janus kinase 2 0.387751
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 0.385436
BRDT bromodomain, testis-specific 0.377354
H2AFJ H2A histone family, member J 0.375434
HIST1H2AJ histone cluster 1, H2aj 0.375434
HIST1H2AM histone cluster 1, H2am 0.375434
HIST1H2AD histone cluster 1, H2ad 0.375434
HIST1H2AH histone cluster 1, H2ah 0.37505
HIST1H2AG histone cluster 1, H2ag 0.373899
SYTL1 synaptotagmin-like 1 0.373516
H2AFY2 H2A histone family, member Y2 0.372366
HIST1H2AB histone cluster 1, H2ab 0.371599
HIST1H2AE histone cluster 1, H2ae 0.371599
H2AFV H2A histone family, member V 0.371216
MED23 mediator complex subunit 23 0.370067
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase 0.369684
SOCS4 suppressor of cytokine signaling 4 0.369301
H2AFB1 H2A histone family, member B1 0.368536
H2AFY H2A histone family, member Y 0.361659
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1 0.358609
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae) 0.349484
POLR1C polymerase (RNA) I polypeptide C, 30kDa 0.347967
TOX3 TOX high mobility group box family member 3 0.334733
HIST2H2AC histone cluster 2, H2ac 0.329084
HIST2H2AA4 histone cluster 2, H2aa4 0.328708
HIST2H2AA3 histone cluster 2, H2aa3 0.328708
IWS1 IWS1 homolog (S. cerevisiae) 0.327205
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae) 0.326078
ELP3 elongator acetyltransferase complex subunit 3 0.318953
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.30924
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) 0.30924
MDFI MyoD family inhibitor 0.308494
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae) 0.299197
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 0.289569
AICDA activation-induced cytidine deaminase 0.28846
DHX30 DEAH (Asp-Glu-Ala-His) box helicase 30 0.282558
AIRE autoimmune regulator 0.280349
HIC2 hypermethylated in cancer 2 0.280349
CDC37 cell division cycle 37 0.280349
RNF40 ring finger protein 40, E3 ubiquitin protein ligase 0.280349
BRD3 bromodomain containing 3 0.27998
PRDM14 PR domain containing 14 0.274101
CAMK1D calcium/calmodulin-dependent protein kinase ID 0.271167
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.2708
GRN granulin 0.26385
ANK1 ankyrin 1, erythrocytic 0.261296
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 0.260202
HDAC3 histone deacetylase 3 0.260202
CDK2 cyclin-dependent kinase 2 0.259473
HOXB3 homeobox B3 0.246046
DEFA1B defensin, alpha 1B 0.240996
GTF2F1 general transcription factor IIF, polypeptide 1, 74kDa 0.234533
TEF thyrotrophic embryonic factor 0.230958
ASB2 ankyrin repeat and SOCS box containing 2 0.229532
FOS FBJ murine osteosarcoma viral oncogene homolog 0.228819
DEFA1 defensin, alpha 1 0.227397
CSTF1 cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa 0.226331
SP3 Sp3 transcription factor 0.224204
HSF1 heat shock transcription factor 1 0.22279
POLR1D polymerase (RNA) I polypeptide D, 16kDa 0.22173
CENPH centromere protein H 0.221025
PRAME preferentially expressed antigen in melanoma 0.219969
RUNX1 runt-related transcription factor 1 0.216111
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B 0.212974
CDK4 cyclin-dependent kinase 4 0.206423
APOBEC3D apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D 0.203361
POLI polymerase (DNA directed) iota 0.201672
HAT1 histone acetyltransferase 1 0.200663
SKI SKI proto-oncogene 0.200328
CENPL centromere protein L 0.199993
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.19733
BRCA1 breast cancer 1, early onset 0.19733
CENPQ centromere protein Q 0.196669
SOCS5 suppressor of cytokine signaling 5 0.190814
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 0.189857
FBXO11 F-box protein 11 0.189222
POLR2G polymerase (RNA) II (DNA directed) polypeptide G 0.186087
NKRF NFKB repressing factor 0.183935
CDK13 cyclin-dependent kinase 13 0.183631
UBE2M ubiquitin-conjugating enzyme E2M 0.180634
BAZ1A bromodomain adjacent to zinc finger domain, 1A 0.180339
RBM23 RNA binding motif protein 23 0.180339
UBE2K ubiquitin-conjugating enzyme E2K 0.180045
ILF3 interleukin enhancer binding factor 3, 90kDa 0.179752
EEF1G eukaryotic translation elongation factor 1 gamma 0.178588
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa 0.178011
PPP1R10 protein phosphatase 1, regulatory subunit 10 0.177724
TFF1 trefoil factor 1 0.17687
JMJD6 jumonji domain containing 6 0.175745
ELF5 E74-like factor 5 (ets domain transcription factor) 0.171149
RNF31 ring finger protein 31 0.170114
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 0.168847
WDR61 WD repeat domain 61 0.165697
UBE2S ubiquitin-conjugating enzyme E2S 0.165
LIG4 ligase IV, DNA, ATP-dependent 0.164315
SMYD3 SET and MYND domain containing 3 0.163865
TXNDC9 thioredoxin domain containing 9 0.1632
CENPN centromere protein N 0.161068
MC5R melanocortin 5 receptor 0.160053
NELFCD negative elongation factor complex member C/D 0.128033
SLK STE20-like kinase 0.12537
FOXC2 forkhead box C2 0.124758
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like 0.121088
NUP133 nucleoporin 133kDa 0.120392
CCNC cyclin C 0.120031
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 0.119879
GPS2 G protein pathway suppressor 2 0.1156
SETX senataxin 0.115113
CFAP20 cilia and flagella associated protein 20 0.114751
PYCR1 pyrroline-5-carboxylate reductase 1 0.114577
CENPU centromere protein U 0.114471
PHF6 PHD finger protein 6 0.112915
NEK9 NIMA-related kinase 9 0.112181
MRC1 mannose receptor, C type 1 0.11042
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 0.109773
TRIM72 tripartite motif containing 72, E3 ubiquitin protein ligase 0.108905
H1F0 H1 histone family, member 0 0.108518
DUSP1 dual specificity phosphatase 1 0.108449
NCL nucleolin 0.107346
CENPT centromere protein T 0.106982
IRS4 insulin receptor substrate 4 0.106666
CUL7 cullin 7 0.106393
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 0.105894
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila) 0.105869
UBE2H ubiquitin-conjugating enzyme E2H 0.10564
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 0.10536
PEG3 paternally expressed 3 0.105309
TRIM32 tripartite motif containing 32 0.104685
TRH thyrotropin-releasing hormone 0.104633
TERF2 telomeric repeat binding factor 2 0.104342
DDB1 damage-specific DNA binding protein 1, 127kDa 0.104315
MATK megakaryocyte-associated tyrosine kinase 0.104129
MCM5 minichromosome maintenance complex component 5 0.103564
WDHD1 WD repeat and HMG-box DNA binding protein 1 0.103455
GADD45B growth arrest and DNA-damage-inducible, beta 0.1034
EOMES eomesodermin 0.103291
MKL1 megakaryoblastic leukemia (translocation) 1 0.102851
SRRM1 serine/arginine repetitive matrix 1 0.101924
MCM10 minichromosome maintenance complex component 10 0.101148
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.100622
CCT4 chaperonin containing TCP1, subunit 4 (delta) 0.100563
EPAS1 endothelial PAS domain protein 1 0.100177
IRS2 insulin receptor substrate 2 0.099577
GATA2 GATA binding protein 2 0.098969
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) 0.098752
USF1 upstream transcription factor 1 0.098691
SLBP stem-loop binding protein 0.097628
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.097439
SNRPN small nuclear ribonucleoprotein polypeptide N 0.096279
PCGF2 polycomb group ring finger 2 0.095755
JAK1 Janus kinase 1 0.095023
CPSF3 cleavage and polyadenylation specific factor 3, 73kDa 0.094282
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G 0.093704
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa 0.093669
CARM1 coactivator-associated arginine methyltransferase 1 0.093358
SOX17 SRY (sex determining region Y)-box 17 0.093289
SGPL1 sphingosine-1-phosphate lyase 1 0.09315
MUL1 mitochondrial E3 ubiquitin protein ligase 1 0.093081
MYOD1 myogenic differentiation 1 0.093081
SUV420H2 suppressor of variegation 4-20 homolog 2 (Drosophila) 0.092734
TWIST1 twist family bHLH transcription factor 1 0.092558
WDR82 WD repeat domain 82 0.092453
CBX8 chromobox homolog 8 0.092312
ZEB2 zinc finger E-box binding homeobox 2 0.092101
HIPK3 homeodomain interacting protein kinase 3 0.09164
LOXL1 lysyl oxidase-like 1 0.090961
TALDO1 transaldolase 1 0.090672
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa 0.090017
ATRX alpha thalassemia/mental retardation syndrome X-linked 0.089872
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C 0.089651
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 0.089429
RPN1 ribophorin I 0.089392
BCOR BCL6 corepressor 0.089244
CUL4A cullin 4A 0.089207
WHSC1 Wolf-Hirschhorn syndrome candidate 1 0.089134
NANOG Nanog homeobox 0.089023
GATA6 GATA binding protein 6 0.088986
KMT2A lysine (K)-specific methyltransferase 2A 0.088276
NUTM1 NUT midline carcinoma, family member 1 0.087788
ACLY ATP citrate lyase 0.087674
APITD1 apoptosis-inducing, TAF9-like domain 1 0.086645
CDC7 cell division cycle 7 0.086375
NCOR1 nuclear receptor corepressor 1 0.086259
MYOCD myocardin 0.085835
FLNB filamin B, beta 0.085602
TRIM5 tripartite motif containing 5 0.085563
GLI2 GLI family zinc finger 2 0.084976
SFN stratifin 0.08395
GMNN geminin, DNA replication inhibitor 0.083871
WRNIP1 Werner helicase interacting protein 1 0.083713
RRM1 ribonucleotide reductase M1 0.083554