trail death-inducing signaling complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A protein complex formed upon binding of TRAIL to its ligand. The complex includes FADD/Mort1 and procaspase-8 addition to the ligand-bound receptor. (Gene Ontology, GO_0031266)
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22 proteins co-occuring with the trail death-inducing signaling complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.93692
FADD Fas (TNFRSF6)-associated via death domain 1.46439
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.35539
CASP10 caspase 10, apoptosis-related cysteine peptidase 1.04381
CFLAR CASP8 and FADD-like apoptosis regulator 0.987806
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.901353
MADD MAP-kinase activating death domain 0.759069
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.600223
DEDD death effector domain containing 0.581758
DIABLO diablo, IAP-binding mitochondrial protein 0.522659
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 0.52225
MTDH metadherin 0.521432
AATF apoptosis antagonizing transcription factor 0.508383
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.499447
NGDN neuroguidin, EIF4E binding protein 0.372749
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 0.339261
TRADD TNFRSF1A-associated via death domain 0.336241
HTRA2 HtrA serine peptidase 2 0.258745
CASP2 caspase 2, apoptosis-related cysteine peptidase 0.190175
BAX BCL2-associated X protein 0.173273
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.173003
TNF tumor necrosis factor 0.160658