tracazolate-6619 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the tracazolate-6619 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACOT11 acyl-CoA thioesterase 11
ANGPTL4 angiopoietin-like 4
APAF1 apoptotic peptidase activating factor 1
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARID1A AT rich interactive domain 1A (SWI-like)
ATF7IP activating transcription factor 7 interacting protein
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BET1L Bet1 golgi vesicular membrane trafficking protein-like
BMP2 bone morphogenetic protein 2
BTG2 BTG family, member 2
C1ORF116 chromosome 1 open reading frame 116
C8A complement component 8, alpha polypeptide
CCDC132 coiled-coil domain containing 132
CCDC30 coiled-coil domain containing 30
CCL2 chemokine (C-C motif) ligand 2
CCND2 cyclin D2
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CHRDL1 chordin-like 1
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CLEC11A C-type lectin domain family 11, member A
CLIC2 chloride intracellular channel 2
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
CPA2 carboxypeptidase A2 (pancreatic)
CSHL1 chorionic somatomammotropin hormone-like 1
CTNNA3 catenin (cadherin-associated protein), alpha 3
DGCR5 DiGeorge syndrome critical region gene 5 (non-protein coding)
DMRT1 doublesex and mab-3 related transcription factor 1
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNM3 dynamin 3
DUSP1 dual specificity phosphatase 1
ENPEP glutamyl aminopeptidase (aminopeptidase A)
EPHA5 EPH receptor A5
ETV7 ets variant 7
FDPS farnesyl diphosphate synthase
FGFR1 fibroblast growth factor receptor 1
FOXN3 forkhead box N3
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GUCA1B guanylate cyclase activator 1B (retina)
HAL histidine ammonia-lyase
HEYL hes-related family bHLH transcription factor with YRPW motif-like
HOOK1 hook microtubule-tethering protein 1
IDS iduronate 2-sulfatase
IFNA17 interferon, alpha 17
ING2 inhibitor of growth family, member 2
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
LAMA2 laminin, alpha 2
LIMD2 LIM domain containing 2
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LOX lysyl oxidase
LSAMP limbic system-associated membrane protein
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP24 matrix metallopeptidase 24 (membrane-inserted)
MUC5B mucin 5B, oligomeric mucus/gel-forming
NPY6R neuropeptide Y receptor Y6 (pseudogene)
ONECUT2 one cut homeobox 2
OR1D2 olfactory receptor, family 1, subfamily D, member 2
PARP8 poly (ADP-ribose) polymerase family, member 8
PAX2 paired box 2
PBOV1 prostate and breast cancer overexpressed 1
PDCD2 programmed cell death 2
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
PID1 phosphotyrosine interaction domain containing 1
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
POU2F2 POU class 2 homeobox 2
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PROL1 proline rich, lacrimal 1
PSD4 pleckstrin and Sec7 domain containing 4
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPRU protein tyrosine phosphatase, receptor type, U
RNASEH2B ribonuclease H2, subunit B
RPL23AP53 ribosomal protein L23a pseudogene 53
RPL35A ribosomal protein L35a
RS1 retinoschisin 1
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SERHL2 serine hydrolase-like 2
SMPX small muscle protein, X-linked
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
SORBS1 sorbin and SH3 domain containing 1
STC1 stanniocalcin 1
TCEAL2 transcription elongation factor A (SII)-like 2
TIAM2 T-cell lymphoma invasion and metastasis 2
TLR5 toll-like receptor 5
TRPV4 transient receptor potential cation channel, subfamily V, member 4
TTC9 tetratricopeptide repeat domain 9
USP46 ubiquitin specific peptidase 46
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
VAC14 Vac14 homolog (S. cerevisiae)
VCAN versican
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae)
WSB1 WD repeat and SOCS box containing 1
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
ZC3H7B zinc finger CCCH-type containing 7B
ZNF74 zinc finger protein 74

decreased expression

Symbol Name
ACOX2 acyl-CoA oxidase 2, branched chain
AGO4 argonaute RISC catalytic component 4
AHDC1 AT hook, DNA binding motif, containing 1
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ALG12 ALG12, alpha-1,6-mannosyltransferase
ALS2CL ALS2 C-terminal like
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
BTF3P12 basic transcription factor 3 pseudogene 12
C7ORF43 chromosome 7 open reading frame 43
CA5BP1 carbonic anhydrase VB pseudogene 1
CASZ1 castor zinc finger 1
CBX4 chromobox homolog 4
CCNO cyclin O
CD70 CD70 molecule
CDON cell adhesion associated, oncogene regulated
CENPJ centromere protein J
CEP131 centrosomal protein 131kDa
CLDN1 claudin 1
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
COL21A1 collagen, type XXI, alpha 1
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DBF4B DBF4 zinc finger B
DENND4B DENN/MADD domain containing 4B
DUSP8 dual specificity phosphatase 8
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1
ERCC2 excision repair cross-complementation group 2
GLS2 glutaminase 2 (liver, mitochondrial)
GMEB1 glucocorticoid modulatory element binding protein 1
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GRAMD1C GRAM domain containing 1C
HDAC7 histone deacetylase 7
HELZ helicase with zinc finger
HLA-DMA major histocompatibility complex, class II, DM alpha
HLX H2.0-like homeobox
IFI44L interferon-induced protein 44-like
IMPACT impact RWD domain protein
INO80D INO80 complex subunit D
IRF2BP1 interferon regulatory factor 2 binding protein 1
KIRREL kin of IRRE like (Drosophila)
KPNA5 karyopherin alpha 5 (importin alpha 6)
LMCD1 LIM and cysteine-rich domains 1
LOC100127972 uncharacterized LOC100127972
MAGEF1 melanoma antigen family F1
MAPK3 mitogen-activated protein kinase 3
MFSD6 major facilitator superfamily domain containing 6
MYO1D myosin ID
NDRG4 NDRG family member 4
NECAP2 NECAP endocytosis associated 2
NTSR1 neurotensin receptor 1 (high affinity)
NXPH4 neurexophilin 4
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDZK1 PDZ domain containing 1
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLK2 polo-like kinase 2
POLM polymerase (DNA directed), mu
RBM19 RNA binding motif protein 19
SAYSD1 SAYSVFN motif domain containing 1
SCAMP5 secretory carrier membrane protein 5
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SIPA1L3 signal-induced proliferation-associated 1 like 3
SKA1 spindle and kinetochore associated complex subunit 1
SLC12A9 solute carrier family 12, member 9
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SLC46A3 solute carrier family 46, member 3
SMA4 glucuronidase, beta pseudogene
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
TAOK1 TAO kinase 1
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
THAP7 THAP domain containing 7
THBS3 thrombospondin 3
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TINAGL1 tubulointerstitial nephritis antigen-like 1
TMCC2 transmembrane and coiled-coil domain family 2
TMEM156 transmembrane protein 156
TPCN1 two pore segment channel 1
TRIM21 tripartite motif containing 21
TUBB2B tubulin, beta 2B class IIb
USP19 ubiquitin specific peptidase 19
USP27X ubiquitin specific peptidase 27, X-linked
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
WDR91 WD repeat domain 91
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
YPEL1 yippee-like 1 (Drosophila)
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZNF205 zinc finger protein 205
ZNF442 zinc finger protein 442
ZNF528 zinc finger protein 528
ZNF606 zinc finger protein 606
ZNF747 zinc finger protein 747
ZNF767P zinc finger family member 767, pseudogene
ZSCAN16 zinc finger and SCAN domain containing 16