tooth agenesis Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A tooth disease characterized by failure to develop on or more missing teeth. (Human Disease Ontology, DOID_0050591)
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Genes

88 genes co-occuring with the disease tooth agenesis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
PAX9 paired box 9 3.33728
MSX1 msh homeobox 1 3.08772
AXIN2 axin 2 2.2627
WNT10A wingless-type MMTV integration site family, member 10A 1.88898
EDARADD EDAR-associated death domain 1.76864
TGFA transforming growth factor, alpha 1.56089
BMP4 bone morphogenetic protein 4 1.45045
IRF6 interferon regulatory factor 6 1.42191
THSD7B thrombospondin, type I, domain containing 7B 1.22128
EDA ectodysplasin A 1.21825
MNX1 motor neuron and pancreas homeobox 1 1.1841
ZNF22 zinc finger protein 22 1.16179
LHX6 LIM homeobox 6 1.1605
MMP20 matrix metallopeptidase 20 1.15581
PITX2 paired-like homeodomain 2 1.10175
DPF3 D4, zinc and double PHD fingers, family 3 1.09251
DSPP dentin sialophosphoprotein 1.08957
ANKS6 ankyrin repeat and sterile alpha motif domain containing 6 1.00625
MSX2 msh homeobox 2 0.996127
OSR2 odd-skipped related transciption factor 2 0.989379
TMEM54 transmembrane protein 54 0.97044
MSRB3 methionine sulfoxide reductase B3 0.939949
CHDH choline dehydrogenase 0.939534
ENAM enamelin 0.919673
WNT11 wingless-type MMTV integration site family, member 11 0.837246
DLX1 distal-less homeobox 1 0.831508
DLX5 distal-less homeobox 5 0.830689
MMP25 matrix metallopeptidase 25 0.820437
AMELX amelogenin, X-linked 0.806488
LHX8 LIM homeobox 8 0.802795
GLI3 GLI family zinc finger 3 0.800333
TUFT1 tuftelin 1 0.791721
WNT8A wingless-type MMTV integration site family, member 8A 0.774932
FGF3 fibroblast growth factor 3 0.751678
FGFR1 fibroblast growth factor receptor 1 0.738271
HOXB2 homeobox B2 0.730976
KLK4 kallikrein-related peptidase 4 0.715618
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2 0.667152
TBX22 T-box 22 0.654067
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1 0.647348
WNT6 wingless-type MMTV integration site family, member 6 0.644981
WNT9B wingless-type MMTV integration site family, member 9B 0.637102
RAD51B RAD51 paralog B 0.633169
NRXN3 neurexin 3 0.62885
DLX4 distal-less homeobox 4 0.615921
FDPS farnesyl diphosphate synthase 0.615529
TRPV3 transient receptor potential cation channel, subfamily V, member 3 0.610838
SPRY4 sprouty homolog 4 (Drosophila) 0.60342
SHH sonic hedgehog 0.588612
EVC2 Ellis van Creveld syndrome 2 0.574217
MIB2 mindbomb E3 ubiquitin protein ligase 2 0.557897
DLX3 distal-less homeobox 3 0.544705
DVL2 dishevelled segment polarity protein 2 0.54393
COL1A1 collagen, type I, alpha 1 0.531154
FGF20 fibroblast growth factor 20 0.528449
SPRY2 sprouty homolog 2 (Drosophila) 0.504207
WNT3 wingless-type MMTV integration site family, member 3 0.498085
PLD2 phospholipase D2 0.488169
COL1A2 collagen, type I, alpha 2 0.483604
CLCN7 chloride channel, voltage-sensitive 7 0.475255
DHH desert hedgehog 0.468063
WNT10B wingless-type MMTV integration site family, member 10B 0.452208
TGFB3 transforming growth factor, beta 3 0.446558
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.4443
HMX1 H6 family homeobox 1 0.438282
PRDM16 PR domain containing 16 0.425139
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) 0.412405
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.400453
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 0.388909
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) 0.384822
REXO1L1P REX1, RNA exonuclease 1 homolog (S. cerevisiae)-like 1, pseudogene 0.346042
FGF10 fibroblast growth factor 10 0.324458
KRT17 keratin 17, type I 0.321181
SRSF2 serine/arginine-rich splicing factor 2 0.31464
CLCN5 chloride channel, voltage-sensitive 5 0.301615
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1 0.283297
ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif, 4 0.258064
AMELY amelogenin, Y-linked 0.255946
FOXC1 forkhead box C1 0.246098
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase 0.245396
MAP2K1 mitogen-activated protein kinase kinase 1 0.237357
FGFR2 fibroblast growth factor receptor 2 0.222136
MUTYH mutY homolog 0.188022
AMBP alpha-1-microglobulin/bikunin precursor 0.180084
SRSF1 serine/arginine-rich splicing factor 1 0.179802
GLI2 GLI family zinc finger 2 0.17896
WNT3A wingless-type MMTV integration site family, member 3A 0.165217
WNT5A wingless-type MMTV integration site family, member 5A 0.160948