tomatidine-7166 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the tomatidine-7166 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2
AK1 adenylate kinase 1
AKR1C2 aldo-keto reductase family 1, member C2
ALOX12 arachidonate 12-lipoxygenase
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
BAIAP3 BAI1-associated protein 3
BCAM basal cell adhesion molecule (Lutheran blood group)
BCL2 B-cell CLL/lymphoma 2
BMP1 bone morphogenetic protein 1
CASP3 caspase 3, apoptosis-related cysteine peptidase
CD8A CD8a molecule
CEP290 centrosomal protein 290kDa
CGREF1 cell growth regulator with EF-hand domain 1
COL8A2 collagen, type VIII, alpha 2
CPD carboxypeptidase D
CST4 cystatin S
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DIXDC1 DIX domain containing 1
DXO decapping exoribonuclease
EFCAB2 EF-hand calcium binding domain 2
EGFR epidermal growth factor receptor
ELSPBP1 epididymal sperm binding protein 1
ENPEP glutamyl aminopeptidase (aminopeptidase A)
EPN2 epsin 2
ESR1 estrogen receptor 1
FGF2 fibroblast growth factor 2 (basic)
FMOD fibromodulin
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GHRHR growth hormone releasing hormone receptor
GMPR guanosine monophosphate reductase
GPR68 G protein-coupled receptor 68
GSTP1 glutathione S-transferase pi 1
GYG2 glycogenin 2
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
HLA-J major histocompatibility complex, class I, J (pseudogene)
IGHM immunoglobulin heavy constant mu
IRF2 interferon regulatory factor 2
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITM2B integral membrane protein 2B
KATNB1 katanin p80 (WD repeat containing) subunit B 1
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KLHL22 kelch-like family member 22
KLHL25 kelch-like family member 25
KPNA5 karyopherin alpha 5 (importin alpha 6)
LIG4 ligase IV, DNA, ATP-dependent
LINC00339 long intergenic non-protein coding RNA 339
LRP12 low density lipoprotein receptor-related protein 12
LTBP4 latent transforming growth factor beta binding protein 4
LYPD1 LY6/PLAUR domain containing 1
LZTFL1 leucine zipper transcription factor-like 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MED14 mediator complex subunit 14
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
MT1F metallothionein 1F
MUC3B mucin 3B, cell surface associated
MYBPC3 myosin binding protein C, cardiac
NF2 neurofibromin 2 (merlin)
NIPAL3 NIPA-like domain containing 3
NPTX1 neuronal pentraxin I
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PGAP3 post-GPI attachment to proteins 3
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
RAB36 RAB36, member RAS oncogene family
RALGPS1 Ral GEF with PH domain and SH3 binding motif 1
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RCAN1 regulator of calcineurin 1
RFXAP regulatory factor X-associated protein
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RNF219 ring finger protein 219
RNMT RNA (guanine-7-) methyltransferase
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
SASH1 SAM and SH3 domain containing 1
SFTPC surfactant protein C
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SRI sorcin
SSPN sarcospan
TFDP3 transcription factor Dp family, member 3
THOC5 THO complex 5
TMEM231 transmembrane protein 231
TNP2 transition protein 2 (during histone to protamine replacement)
TUBA4B tubulin, alpha 4b
TULP1 tubby like protein 1
UBE2I ubiquitin-conjugating enzyme E2I
USP34 ubiquitin specific peptidase 34
VAMP5 vesicle-associated membrane protein 5
WWP2 WW domain containing E3 ubiquitin protein ligase 2
ZC3H7B zinc finger CCCH-type containing 7B
ZCCHC24 zinc finger, CCHC domain containing 24
ZMIZ2 zinc finger, MIZ-type containing 2

decreased expression

Symbol Name
AHDC1 AT hook, DNA binding motif, containing 1
ALPK1 alpha-kinase 1
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1
ARMC7 armadillo repeat containing 7
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BBS10 Bardet-Biedl syndrome 10
BCORL1 BCL6 corepressor-like 1
BTBD2 BTB (POZ) domain containing 2
C17ORF70 chromosome 17 open reading frame 70
C19ORF40 chromosome 19 open reading frame 40
C7ORF43 chromosome 7 open reading frame 43
C9ORF40 chromosome 9 open reading frame 40
CAPN15 calpain 15
CEP85 centrosomal protein 85kDa
CEP97 centrosomal protein 97kDa
CHIC2 cysteine-rich hydrophobic domain 2
CHPF chondroitin polymerizing factor
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CUEDC1 CUE domain containing 1
CXORF56 chromosome X open reading frame 56
DCAF16 DDB1 and CUL4 associated factor 16
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DUSP5 dual specificity phosphatase 5
EPPK1 epiplakin 1
FAM114A1 family with sequence similarity 114, member A1
FAM179B family with sequence similarity 179, member B
FGGY FGGY carbohydrate kinase domain containing
FKBPL FK506 binding protein like
FUZ fuzzy planar cell polarity protein
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
GUSBP3 glucuronidase, beta pseudogene 3
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HOOK1 hook microtubule-tethering protein 1
HYOU1 hypoxia up-regulated 1
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1)
INSIG2 insulin induced gene 2
ITPKC inositol-trisphosphate 3-kinase C
KATNBL1 katanin p80 subunit B-like 1
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KCTD20 potassium channel tetramerization domain containing 20
KIFC1 kinesin family member C1
LHFPL2 lipoma HMGIC fusion partner-like 2
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LMNB1 lamin B1
LOC202181 SUMO-interacting motifs containing 1 pseudogene
MAMLD1 mastermind-like domain containing 1
MAPK12 mitogen-activated protein kinase 12
MAPKBP1 mitogen-activated protein kinase binding protein 1
MAST3 microtubule associated serine/threonine kinase 3
MED15 mediator complex subunit 15
MNX1 motor neuron and pancreas homeobox 1
MSX1 msh homeobox 1
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NARFL nuclear prelamin A recognition factor-like
NECAB3 N-terminal EF-hand calcium binding protein 3
NEO1 neogenin 1
NOTCH1 notch 1
NR1H2 nuclear receptor subfamily 1, group H, member 2
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
PARP16 poly (ADP-ribose) polymerase family, member 16
PCSK7 proprotein convertase subtilisin/kexin type 7
PHACTR4 phosphatase and actin regulator 4
PLEKHO1 pleckstrin homology domain containing, family O member 1
PRR15L proline rich 15-like
PYGB phosphorylase, glycogen; brain
RCOR3 REST corepressor 3
RIBC2 RIB43A domain with coiled-coils 2
RNF38 ring finger protein 38
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
SAMHD1 SAM domain and HD domain 1
SAV1 salvador family WW domain containing protein 1
SCAMP4 secretory carrier membrane protein 4
SHROOM2 shroom family member 2
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SMAD5 SMAD family member 5
SMAD7 SMAD family member 7
SNX16 sorting nexin 16
STAG3 stromal antigen 3
STK16 serine/threonine kinase 16
TBX19 T-box 19
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM159 transmembrane protein 159
TOE1 target of EGR1, member 1 (nuclear)
TRIM25 tripartite motif containing 25
TSPAN5 tetraspanin 5
TUBA3C tubulin, alpha 3c
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
USP36 ubiquitin specific peptidase 36
WEE1 WEE1 G2 checkpoint kinase
ZNF14 zinc finger protein 14
ZNF184 zinc finger protein 184
ZNF562 zinc finger protein 562
ZNF574 zinc finger protein 574
ZNF7 zinc finger protein 7
ZNF83 zinc finger protein 83
ZNHIT2 zinc finger, HIT-type containing 2