tiratricol-7011 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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195 genes differentially expressed following the tiratricol-7011 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ANKRD36 ankyrin repeat domain 36
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BLZF1 basic leucine zipper nuclear factor 1
C15ORF39 chromosome 15 open reading frame 39
C7ORF43 chromosome 7 open reading frame 43
CABP1 calcium binding protein 1
CACFD1 calcium channel flower domain containing 1
CAMK1 calcium/calmodulin-dependent protein kinase I
CDKL3 cyclin-dependent kinase-like 3
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CFLAR CASP8 and FADD-like apoptosis regulator
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CLCN5 chloride channel, voltage-sensitive 5
CLDN6 claudin 6
CLMN calmin (calponin-like, transmembrane)
CTNNA2 catenin (cadherin-associated protein), alpha 2
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DESI2 desumoylating isopeptidase 2
DSTYK dual serine/threonine and tyrosine protein kinase
ENPEP glutamyl aminopeptidase (aminopeptidase A)
EWSR1 EWS RNA-binding protein 1
FSTL3 follistatin-like 3 (secreted glycoprotein)
FZD1 frizzled class receptor 1
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GLS glutaminase
GOSR2 golgi SNAP receptor complex member 2
GPATCH4 G patch domain containing 4
GRB10 growth factor receptor-bound protein 10
GRM1 glutamate receptor, metabotropic 1
GSTA3 glutathione S-transferase alpha 3
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HHAT hedgehog acyltransferase
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HPS1 Hermansky-Pudlak syndrome 1
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
IL17RC interleukin 17 receptor C
IL6ST interleukin 6 signal transducer
INO80D INO80 complex subunit D
IPO5 importin 5
IRS2 insulin receptor substrate 2
JAG1 jagged 1
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KDM4A lysine (K)-specific demethylase 4A
KIAA0125 KIAA0125
KIF25 kinesin family member 25
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
KRT31 keratin 31, type I
LMNA lamin A/C
LOC730101 uncharacterized LOC730101
MAPK14 mitogen-activated protein kinase 14
METTL7A methyltransferase like 7A
MLXIPL MLX interacting protein-like
N4BP2L2 NEDD4 binding protein 2-like 2
NCKIPSD NCK interacting protein with SH3 domain
NDN necdin, melanoma antigen (MAGE) family member
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa
NFX1 nuclear transcription factor, X-box binding 1
OASL 2'-5'-oligoadenylate synthetase-like
ONECUT2 one cut homeobox 2
PACS1 phosphofurin acidic cluster sorting protein 1
PAX5 paired box 5
PDE4DIP phosphodiesterase 4D interacting protein
PDLIM7 PDZ and LIM domain 7 (enigma)
PHF20L1 PHD finger protein 20-like 1
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
POM121L2 POM121 transmembrane nucleoporin-like 2
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRB1 proline-rich protein BstNI subfamily 1
RANBP3 RAN binding protein 3
RNF2 ring finger protein 2
RPH3AL rabphilin 3A-like (without C2 domains)
RPL10L ribosomal protein L10-like
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
RUNX1 runt-related transcription factor 1
SC5D sterol-C5-desaturase
SCAPER S-phase cyclin A-associated protein in the ER
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SETD1A SET domain containing 1A
SH2B3 SH2B adaptor protein 3
SIX1 SIX homeobox 1
SLC6A13 solute carrier family 6 (neurotransmitter transporter), member 13
SMG5 SMG5 nonsense mediated mRNA decay factor
SPRY2 sprouty homolog 2 (Drosophila)
SRSF5 serine/arginine-rich splicing factor 5
THNSL2 threonine synthase-like 2 (S. cerevisiae)
TLN1 talin 1
TRAK1 trafficking protein, kinesin binding 1
TTC33 tetratricopeptide repeat domain 33
USB1 U6 snRNA biogenesis 1
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
ZBTB7B zinc finger and BTB domain containing 7B
ZNF10 zinc finger protein 10
ZNF609 zinc finger protein 609

decreased expression

Symbol Name
ABHD14A abhydrolase domain containing 14A
ACOT8 acyl-CoA thioesterase 8
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
BAK1 BCL2-antagonist/killer 1
BMP4 bone morphogenetic protein 4
CCDC92 coiled-coil domain containing 92
CCNT1 cyclin T1
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CEP131 centrosomal protein 131kDa
CHMP6 charged multivesicular body protein 6
CHPF chondroitin polymerizing factor
CIDEC cell death-inducing DFFA-like effector c
CLDN4 claudin 4
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CLSPN claspin
COPS7B COP9 signalosome subunit 7B
CPTP ceramide-1-phosphate transfer protein
CTAGE9 CTAGE family, member 9
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DDB1 damage-specific DNA binding protein 1, 127kDa
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DNM1 dynamin 1
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
ERCC5 excision repair cross-complementation group 5
EXTL2 exostosin-like glycosyltransferase 2
FHOD1 formin homology 2 domain containing 1
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
FOXK2 forkhead box K2
FSD1 fibronectin type III and SPRY domain containing 1
HIRIP3 HIRA interacting protein 3
HTT huntingtin
IGFLR1 IGF-like family receptor 1
IGSF1 immunoglobulin superfamily, member 1
IRF2BP1 interferon regulatory factor 2 binding protein 1
KIAA0753 KIAA0753
KLHL26 kelch-like family member 26
LIN7B lin-7 homolog B (C. elegans)
LOC100287590 uncharacterized LOC100287590
LRRC8E leucine rich repeat containing 8 family, member E
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MBOAT2 membrane bound O-acyltransferase domain containing 2
MIS18BP1 MIS18 binding protein 1
MORC3 MORC family CW-type zinc finger 3
MYL5 myosin, light chain 5, regulatory
NECAP2 NECAP endocytosis associated 2
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
ORAI3 ORAI calcium release-activated calcium modulator 3
PADI2 peptidyl arginine deiminase, type II
PARD6A par-6 family cell polarity regulator alpha
PBLD phenazine biosynthesis-like protein domain containing
PDLIM2 PDZ and LIM domain 2 (mystique)
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PODXL podocalyxin-like
PPT2 palmitoyl-protein thioesterase 2
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PYGB phosphorylase, glycogen; brain
RAB17 RAB17, member RAS oncogene family
RBL1 retinoblastoma-like 1
RPL13P5 ribosomal protein L13 pseudogene 5
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
S100A4 S100 calcium binding protein A4
SCAMP4 secretory carrier membrane protein 4
SCAMP5 secretory carrier membrane protein 5
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SETD8 SET domain containing (lysine methyltransferase) 8
SH2B2 SH2B adaptor protein 2
SIRT2 sirtuin 2
SLC12A8 solute carrier family 12, member 8
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLC41A3 solute carrier family 41, member 3
SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adaptor protein
SLC4A2 solute carrier family 4 (anion exchanger), member 2
SPECC1L sperm antigen with calponin homology and coiled-coil domains 1-like
STAG3 stromal antigen 3
SUSD6 sushi domain containing 6
SYNGR3 synaptogyrin 3
TCTN1 tectonic family member 1
THBS3 thrombospondin 3
TMEM115 transmembrane protein 115
TMEM231 transmembrane protein 231
TMEM260 transmembrane protein 260
TTLL1 tubulin tyrosine ligase-like family member 1
TXNL4B thioredoxin-like 4B
UBIAD1 UbiA prenyltransferase domain containing 1
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WBP2 WW domain binding protein 2
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZDHHC18 zinc finger, DHHC-type containing 18
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF276 zinc finger protein 276
ZNF675 zinc finger protein 675
ZNF813 zinc finger protein 813