ticarcillin-6146 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the ticarcillin-6146 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACP5 acid phosphatase 5, tartrate resistant
ALAS2 5'-aminolevulinate synthase 2
AMDHD2 amidohydrolase domain containing 2
ANGEL2 angel homolog 2 (Drosophila)
AREG amphiregulin
ARTN artemin
ATP9B ATPase, class II, type 9B
BCAS3 breast carcinoma amplified sequence 3
BCL2 B-cell CLL/lymphoma 2
BEST2 bestrophin 2
C11ORF16 chromosome 11 open reading frame 16
C17ORF80 chromosome 17 open reading frame 80
CALCA calcitonin-related polypeptide alpha
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CCL13 chemokine (C-C motif) ligand 13
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CEP250 centrosomal protein 250kDa
CES3 carboxylesterase 3
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CLTA clathrin, light chain A
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
COL6A1 collagen, type VI, alpha 1
DLG3 discs, large homolog 3 (Drosophila)
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
EPHA4 EPH receptor A4
FAIM2 Fas apoptotic inhibitory molecule 2
FAM182B family with sequence similarity 182, member B
FBXO31 F-box protein 31
FCAR Fc fragment of IgA receptor
FERMT1 fermitin family member 1
FOXE1 forkhead box E1
FRS2 fibroblast growth factor receptor substrate 2
FST follistatin
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GNRHR gonadotropin-releasing hormone receptor
GPATCH4 G patch domain containing 4
GRAMD3 GRAM domain containing 3
HLA-DOA major histocompatibility complex, class II, DO alpha
HUS1 HUS1 checkpoint homolog (S. pombe)
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
INSL5 insulin-like 5
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
IRF4 interferon regulatory factor 4
KAT8 K(lysine) acetyltransferase 8
KCNIP1 Kv channel interacting protein 1
KCNK13 potassium channel, two pore domain subfamily K, member 13
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
KIR2DL2 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KLHL36 kelch-like family member 36
KLK6 kallikrein-related peptidase 6
LAMC2 laminin, gamma 2
LATS1 large tumor suppressor kinase 1
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1
MBNL2 muscleblind-like splicing regulator 2
MISP mitotic spindle positioning
NCS1 neuronal calcium sensor 1
NES nestin
NR1I2 nuclear receptor subfamily 1, group I, member 2
NTNG1 netrin G1
ONECUT2 one cut homeobox 2
PER3 period circadian clock 3
PFN2 profilin 2
PHC3 polyhomeotic homolog 3 (Drosophila)
PLCG1 phospholipase C, gamma 1
POFUT1 protein O-fucosyltransferase 1
POU3F4 POU class 3 homeobox 4
PPAP2B phosphatidic acid phosphatase type 2B
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PRLH prolactin releasing hormone
RAP2B RAP2B, member of RAS oncogene family
RARA retinoic acid receptor, alpha
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
REC8 REC8 meiotic recombination protein
RERE arginine-glutamic acid dipeptide (RE) repeats
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SAA4 serum amyloid A4, constitutive
SGK2 serum/glucocorticoid regulated kinase 2
SH2D3A SH2 domain containing 3A
SIX1 SIX homeobox 1
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SNPH syntaphilin
STAP1 signal transducing adaptor family member 1
STX11 syntaxin 11
TCF3 transcription factor 3
TG thyroglobulin
THBS1 thrombospondin 1
TLN2 talin 2
TMCC1 transmembrane and coiled-coil domain family 1
TMEM51 transmembrane protein 51
TRD T cell receptor delta locus
U2AF2 U2 small nuclear RNA auxiliary factor 2
UGT2B4 UDP glucuronosyltransferase 2 family, polypeptide B4
VEGFC vascular endothelial growth factor C
WDR59 WD repeat domain 59
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
ZBTB20 zinc finger and BTB domain containing 20

decreased expression

Symbol Name
AAR2 AAR2 splicing factor homolog (S. cerevisiae)
ACVR2A activin A receptor, type IIA
AES amino-terminal enhancer of split
AGBL5 ATP/GTP binding protein-like 5
AOAH acyloxyacyl hydrolase (neutrophil)
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
ARID3B AT rich interactive domain 3B (BRIGHT-like)
BTF3P12 basic transcription factor 3 pseudogene 12
C11ORF30 chromosome 11 open reading frame 30
C5AR1 complement component 5a receptor 1
CA5BP1 carbonic anhydrase VB pseudogene 1
CCDC6 coiled-coil domain containing 6
CDADC1 cytidine and dCMP deaminase domain containing 1
CDR2L cerebellar degeneration-related protein 2-like
CLCN5 chloride channel, voltage-sensitive 5
COL15A1 collagen, type XV, alpha 1
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
CRABP2 cellular retinoic acid binding protein 2
CTDNEP1 CTD nuclear envelope phosphatase 1
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DEPDC5 DEP domain containing 5
DHRS11 dehydrogenase/reductase (SDR family) member 11
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1
EXOC2 exocyst complex component 2
EYA3 EYA transcriptional coactivator and phosphatase 3
F3 coagulation factor III (thromboplastin, tissue factor)
FAM127A family with sequence similarity 127, member A
FBXL7 F-box and leucine-rich repeat protein 7
FJX1 four jointed box 1 (Drosophila)
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GEMIN8 gem (nuclear organelle) associated protein 8
HINFP histone H4 transcription factor
HIST1H1E histone cluster 1, H1e
HYAL2 hyaluronoglucosaminidase 2
HYAL3 hyaluronoglucosaminidase 3
IFT74 intraflagellar transport 74
IL24 interleukin 24
INA internexin neuronal intermediate filament protein, alpha
JUNB jun B proto-oncogene
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KDM7A lysine (K)-specific demethylase 7A
KIAA0754 KIAA0754
KLF2 Kruppel-like factor 2
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
MANSC1 MANSC domain containing 1
MBNL3 muscleblind-like splicing regulator 3
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NDE1 nudE neurodevelopment protein 1
NDEL1 nudE neurodevelopment protein 1-like 1
NOD2 nucleotide-binding oligomerization domain containing 2
NR1D2 nuclear receptor subfamily 1, group D, member 2
NUBPL nucleotide binding protein-like
OR2B6 olfactory receptor, family 2, subfamily B, member 6
PANX1 pannexin 1
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PRAF2 PRA1 domain family, member 2
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PSKH1 protein serine kinase H1
PYGB phosphorylase, glycogen; brain
QTRT1 queuine tRNA-ribosyltransferase 1
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RGS13 regulator of G-protein signaling 13
RHBDF1 rhomboid 5 homolog 1 (Drosophila)
RHOH ras homolog family member H
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RPAP1 RNA polymerase II associated protein 1
SCGB2A2 secretoglobin, family 2A, member 2
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLITRK5 SLIT and NTRK-like family, member 5
SMG9 SMG9 nonsense mediated mRNA decay factor
SNX16 sorting nexin 16
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
STBD1 starch binding domain 1
SUN2 Sad1 and UNC84 domain containing 2
TAS2R10 taste receptor, type 2, member 10
TCEA2 transcription elongation factor A (SII), 2
THBS3 thrombospondin 3
THBS4 thrombospondin 4
TMEM159 transmembrane protein 159
TMEM209 transmembrane protein 209
TMEM8A transmembrane protein 8A
TOR4A torsin family 4, member A
TTLL1 tubulin tyrosine ligase-like family member 1
USP19 ubiquitin specific peptidase 19
VANGL1 VANGL planar cell polarity protein 1
WDR33 WD repeat domain 33
WNT10B wingless-type MMTV integration site family, member 10B
XAB2 XPA binding protein 2
ZBTB6 zinc finger and BTB domain containing 6
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF322P1 zinc finger protein 322 pseudogene 1
ZNF428 zinc finger protein 428
ZNF493 zinc finger protein 493
ZNF8 zinc finger protein 8