tiapride-7362 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the tiapride-7362 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRL1 adhesion G protein-coupled receptor L1
AK5 adenylate kinase 5
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ALDH6A1 aldehyde dehydrogenase 6 family, member A1
ANKRD1 ankyrin repeat domain 1 (cardiac muscle)
ARID1A AT rich interactive domain 1A (SWI-like)
BCL2 B-cell CLL/lymphoma 2
BGN biglycan
BMP7 bone morphogenetic protein 7
C17ORF70 chromosome 17 open reading frame 70
CABIN1 calcineurin binding protein 1
CD33 CD33 molecule
CD4 CD4 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CDC42 cell division cycle 42
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CES2 carboxylesterase 2
CHRDL1 chordin-like 1
CLDN18 claudin 18
CNR2 cannabinoid receptor 2 (macrophage)
COPE coatomer protein complex, subunit epsilon
CPNE7 copine VII
CSHL1 chorionic somatomammotropin hormone-like 1
CSN3 casein kappa
CYP2U1 cytochrome P450, family 2, subfamily U, polypeptide 1
DDN dendrin
DFNB31 deafness, autosomal recessive 31
E2F4 E2F transcription factor 4, p107/p130-binding
EDA ectodysplasin A
EGR1 early growth response 1
EHF ets homologous factor
EMX1 empty spiracles homeobox 1
FYB FYN binding protein
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
GPSM3 G-protein signaling modulator 3
HAO2 hydroxyacid oxidase 2 (long chain)
HIST1H4E histone cluster 1, H4e
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HLF hepatic leukemia factor
ICA1 islet cell autoantigen 1, 69kDa
IL17RA interleukin 17 receptor A
IL6 interleukin 6
JAG1 jagged 1
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LIG3 ligase III, DNA, ATP-dependent
LMO2 LIM domain only 2 (rhombotin-like 1)
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
MFAP3 microfibrillar-associated protein 3
MPPE1 metallophosphoesterase 1
NAGLU N-acetylglucosaminidase, alpha
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NKX3-2 NK3 homeobox 2
NPC1L1 NPC1-like 1
NPFFR1 neuropeptide FF receptor 1
NRF1 nuclear respiratory factor 1
NUDC nudC nuclear distribution protein
OCA2 oculocutaneous albinism II
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PDIA2 protein disulfide isomerase family A, member 2
PDK3 pyruvate dehydrogenase kinase, isozyme 3
PHOX2A paired-like homeobox 2a
PODNL1 podocan-like 1
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PRR4 proline rich 4 (lacrimal)
PSD4 pleckstrin and Sec7 domain containing 4
PTCRA pre T-cell antigen receptor alpha
RAB11B RAB11B, member RAS oncogene family
RAB27B RAB27B, member RAS oncogene family
RAD52 RAD52 homolog (S. cerevisiae)
RANBP1 RAN binding protein 1
RASSF4 Ras association (RalGDS/AF-6) domain family member 4
REEP1 receptor accessory protein 1
RGS10 regulator of G-protein signaling 10
RIN3 Ras and Rab interactor 3
ROM1 retinal outer segment membrane protein 1
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SERHL2 serine hydrolase-like 2
SLC17A2 solute carrier family 17, member 2
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SND1-IT1 SND1 intronic transcript 1
SOX4 SRY (sex determining region Y)-box 4
SSX3 synovial sarcoma, X breakpoint 3
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
TRIM14 tripartite motif containing 14
UBQLN4 ubiquilin 4
VAV2 vav 2 guanine nucleotide exchange factor
WNT3 wingless-type MMTV integration site family, member 3
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
YIPF2 Yip1 domain family, member 2
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF205 zinc finger protein 205
ZNF44 zinc finger protein 44
ZNF471 zinc finger protein 471
ZNF549 zinc finger protein 549

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ACVR2B activin A receptor, type IIB
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3
ADAMTSL3 ADAMTS-like 3
AEN apoptosis enhancing nuclease
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ALS2CL ALS2 C-terminal like
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
BAHD1 bromo adjacent homology domain containing 1
BBS7 Bardet-Biedl syndrome 7
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide
BLOC1S1 biogenesis of lysosomal organelles complex-1, subunit 1
BRWD1 bromodomain and WD repeat domain containing 1
C17ORF80 chromosome 17 open reading frame 80
C1ORF159 chromosome 1 open reading frame 159
CA5BP1 carbonic anhydrase VB pseudogene 1
CAPN15 calpain 15
CBX8 chromobox homolog 8
CCNE1 cyclin E1
CLEC16A C-type lectin domain family 16, member A
CLEC2B C-type lectin domain family 2, member B
CLIP4 CAP-GLY domain containing linker protein family, member 4
COQ6 coenzyme Q6 monooxygenase
CUL9 cullin 9
CXORF56 chromosome X open reading frame 56
DAAM1 dishevelled associated activator of morphogenesis 1
DIXDC1 DIX domain containing 1
DOCK1 dedicator of cytokinesis 1
EFNA4 ephrin-A4
ELOVL4 ELOVL fatty acid elongase 4
ELP6 elongator acetyltransferase complex subunit 6
EPPK1 epiplakin 1
ERN2 endoplasmic reticulum to nucleus signaling 2
ETAA1 Ewing tumor-associated antigen 1
F3 coagulation factor III (thromboplastin, tissue factor)
FAM50B family with sequence similarity 50, member B
FBXL2 F-box and leucine-rich repeat protein 2
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GPALPP1 GPALPP motifs containing 1
GPBP1L1 GC-rich promoter binding protein 1-like 1
HELZ helicase with zinc finger
HIST1H2AI histone cluster 1, H2ai
HIST1H2AJ histone cluster 1, H2aj
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IREB2 iron-responsive element binding protein 2
JAM3 junctional adhesion molecule 3
KIAA0513 KIAA0513
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LHX6 LIM homeobox 6
MANEA mannosidase, endo-alpha
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MEIS3P1 Meis homeobox 3 pseudogene 1
MITF microphthalmia-associated transcription factor
MSRA methionine sulfoxide reductase A
NABP2 nucleic acid binding protein 2
NINJ1 ninjurin 1
NLK nemo-like kinase
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PEX13 peroxisomal biogenesis factor 13
PHC1 polyhomeotic homolog 1 (Drosophila)
PHKG2 phosphorylase kinase, gamma 2 (testis)
PNRC1 proline-rich nuclear receptor coactivator 1
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
PRMT7 protein arginine methyltransferase 7
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
REEP4 receptor accessory protein 4
RIN1 Ras and Rab interactor 1
RNF170 ring finger protein 170
RNF25 ring finger protein 25
SETD6 SET domain containing 6
SIX1 SIX homeobox 1
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC25A40 solute carrier family 25, member 40
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SMIM8 small integral membrane protein 8
SP140L SP140 nuclear body protein-like
STAC SH3 and cysteine rich domain
SYNE2 spectrin repeat containing, nuclear envelope 2
TMCC2 transmembrane and coiled-coil domain family 2
TSKU tsukushi, small leucine rich proteoglycan
UEVLD UEV and lactate/malate dehyrogenase domains
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
USP6 ubiquitin specific peptidase 6
VASP vasodilator-stimulated phosphoprotein
ZNF408 zinc finger protein 408
ZNF623 zinc finger protein 623
ZNF671 zinc finger protein 671