tiapride-4686 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the tiapride-4686 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACVR1 activin A receptor, type I
ADM adrenomedullin
AGFG1 ArfGAP with FG repeats 1
AGGF1 angiogenic factor with G patch and FHA domains 1
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
AMPD3 adenosine monophosphate deaminase 3
APC adenomatous polyposis coli
AQP3 aquaporin 3 (Gill blood group)
BET1L Bet1 golgi vesicular membrane trafficking protein-like
BMP1 bone morphogenetic protein 1
C19ORF73 chromosome 19 open reading frame 73
CARD9 caspase recruitment domain family, member 9
CCDC121 coiled-coil domain containing 121
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CD47 CD47 molecule
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CEP76 centrosomal protein 76kDa
CHRM3 cholinergic receptor, muscarinic 3
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
CREM cAMP responsive element modulator
CRYBB2P1 crystallin, beta B2 pseudogene 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DGCR8 DGCR8 microprocessor complex subunit
EDRF1 erythroid differentiation regulatory factor 1
EFNB3 ephrin-B3
EZR ezrin
FBXL5 F-box and leucine-rich repeat protein 5
FGFR2 fibroblast growth factor receptor 2
FLOT1 flotillin 1
GID4 GID complex subunit 4
GPATCH4 G patch domain containing 4
HIC2 hypermethylated in cancer 2
HOXB2 homeobox B2
IDUA iduronidase, alpha-L-
IKZF1 IKAROS family zinc finger 1 (Ikaros)
ITM2B integral membrane protein 2B
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3
KIF25 kinesin family member 25
KLF12 Kruppel-like factor 12
KLHL20 kelch-like family member 20
LAMC2 laminin, gamma 2
LAMP1 lysosomal-associated membrane protein 1
LAT2 linker for activation of T cells family, member 2
LIMCH1 LIM and calponin homology domains 1
LPIN2 lipin 2
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
LRP2 low density lipoprotein receptor-related protein 2
LZTS3 leucine zipper, putative tumor suppressor family member 3
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MLF1 myeloid leukemia factor 1
MR1 major histocompatibility complex, class I-related
NDRG2 NDRG family member 2
NEK9 NIMA-related kinase 9
NFE2L3 nuclear factor, erythroid 2-like 3
NME5 NME/NM23 family member 5
NR2E3 nuclear receptor subfamily 2, group E, member 3
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NRL neural retina leucine zipper
NT5M 5',3'-nucleotidase, mitochondrial
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4
OSBPL10 oxysterol binding protein-like 10
PARVA parvin, alpha
PCDHA6 protocadherin alpha 6
PDE4DIP phosphodiesterase 4D interacting protein
PDE8B phosphodiesterase 8B
PER3 period circadian clock 3
PHF1 PHD finger protein 1
PLAC1 placenta-specific 1
POU4F1 POU class 4 homeobox 1
PRKCA protein kinase C, alpha
PRKD3 protein kinase D3
PRND prion protein 2 (dublet)
QSER1 glutamine and serine rich 1
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
RXRB retinoid X receptor, beta
SAP30 Sin3A-associated protein, 30kDa
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLC35E2 solute carrier family 35, member E2
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
STAG3L4 stromal antigen 3-like 4 (pseudogene)
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TAPBP TAP binding protein (tapasin)
TGFB2 transforming growth factor, beta 2
THSD4 thrombospondin, type I, domain containing 4
TM6SF1 transmembrane 6 superfamily member 1
TMEM242 transmembrane protein 242
TROVE2 TROVE domain family, member 2
UBE3A ubiquitin protein ligase E3A
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast)
VAMP4 vesicle-associated membrane protein 4
WIPF1 WAS/WASL interacting protein family, member 1
YTHDC2 YTH domain containing 2
ZC3H13 zinc finger CCCH-type containing 13
ZNF226 zinc finger protein 226
ZNF304 zinc finger protein 304
ZNF362 zinc finger protein 362
ZNF41 zinc finger protein 41

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
AHR aryl hydrocarbon receptor
ALPK1 alpha-kinase 1
AMT aminomethyltransferase
ARHGAP4 Rho GTPase activating protein 4
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ATAD5 ATPase family, AAA domain containing 5
BBC3 BCL2 binding component 3
BFSP1 beaded filament structural protein 1, filensin
BMP4 bone morphogenetic protein 4
C11ORF80 chromosome 11 open reading frame 80
C1QTNF3 C1q and tumor necrosis factor related protein 3
C22ORF46 chromosome 22 open reading frame 46
C2ORF27A chromosome 2 open reading frame 27A
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CD79B CD79b molecule, immunoglobulin-associated beta
CDADC1 cytidine and dCMP deaminase domain containing 1
CDKL3 cyclin-dependent kinase-like 3
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CIR1 corepressor interacting with RBPJ, 1
CLCN6 chloride channel, voltage-sensitive 6
CLSPN claspin
CNR2 cannabinoid receptor 2 (macrophage)
CSF1R colony stimulating factor 1 receptor
CUL9 cullin 9
DCAF13 DDB1 and CUL4 associated factor 13
DCAF16 DDB1 and CUL4 associated factor 16
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DNALI1 dynein, axonemal, light intermediate chain 1
DSPP dentin sialophosphoprotein
DUSP2 dual specificity phosphatase 2
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
ELSPBP1 epididymal sperm binding protein 1
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
EYA3 EYA transcriptional coactivator and phosphatase 3
FAM131A family with sequence similarity 131, member A
FBXW12 F-box and WD repeat domain containing 12
FGF23 fibroblast growth factor 23
FLT4 fms-related tyrosine kinase 4
GADD45G growth arrest and DNA-damage-inducible, gamma
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GINS4 GINS complex subunit 4 (Sld5 homolog)
GLRA1 glycine receptor, alpha 1
GPC3 glypican 3
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HDAC11 histone deacetylase 11
HIST1H1D histone cluster 1, H1d
HIST1H2BN histone cluster 1, H2bn
HIST1H2BO histone cluster 1, H2bo
HLA-J major histocompatibility complex, class I, J (pseudogene)
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HOXC8 homeobox C8
IL12RB1 interleukin 12 receptor, beta 1
IRF1 interferon regulatory factor 1
KCNK12 potassium channel, two pore domain subfamily K, member 12
KRT31 keratin 31, type I
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LRRC23 leucine rich repeat containing 23
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MBNL3 muscleblind-like splicing regulator 3
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MMP15 matrix metallopeptidase 15 (membrane-inserted)
NACA2 nascent polypeptide-associated complex alpha subunit 2
NKX3-2 NK3 homeobox 2
PDE12 phosphodiesterase 12
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PGPEP1 pyroglutamyl-peptidase I
PMEL premelanosome protein
POMT2 protein-O-mannosyltransferase 2
PRB3 proline-rich protein BstNI subfamily 3
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
RAB3D RAB3D, member RAS oncogene family
RCAN3 RCAN family member 3
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RNF126P1 ring finger protein 126 pseudogene 1
RPAP2 RNA polymerase II associated protein 2
RUSC2 RUN and SH3 domain containing 2
S100A9 S100 calcium binding protein A9
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SNTA1 syntrophin, alpha 1
SPINK4 serine peptidase inhibitor, Kazal type 4
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STEAP4 STEAP family member 4
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TIGD6 tigger transposable element derived 6
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TRIM25 tripartite motif containing 25
TUBB2B tubulin, beta 2B class IIb
UPK2 uroplakin 2
VASH2 vasohibin 2
WDR76 WD repeat domain 76
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZNF134 zinc finger protein 134
ZNF652 zinc finger protein 652