tiabendazole-2479 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the tiabendazole-2479 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTC1 actin, alpha, cardiac muscle 1
ACTN2 actinin, alpha 2
ALX4 ALX homeobox 4
AMH anti-Mullerian hormone
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2
ARHGAP26 Rho GTPase activating protein 26
ATP10B ATPase, class V, type 10B
C22ORF24 chromosome 22 open reading frame 24
C7ORF43 chromosome 7 open reading frame 43
CD248 CD248 molecule, endosialin
CDC42 cell division cycle 42
CFAP69 cilia and flagella associated protein 69
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CREM cAMP responsive element modulator
CRYGD crystallin, gamma D
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DCAF15 DDB1 and CUL4 associated factor 15
DEFA4 defensin, alpha 4, corticostatin
DGCR5 DiGeorge syndrome critical region gene 5 (non-protein coding)
DGKE diacylglycerol kinase, epsilon 64kDa
DLK2 delta-like 2 homolog (Drosophila)
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EFR3B EFR3 homolog B (S. cerevisiae)
ENG endoglin
FBXL18 F-box and leucine-rich repeat protein 18
FBXL7 F-box and leucine-rich repeat protein 7
FOXA1 forkhead box A1
FZD4 frizzled class receptor 4
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GPR22 G protein-coupled receptor 22
GPX2 glutathione peroxidase 2
GRB7 growth factor receptor-bound protein 7
H2AFX H2A histone family, member X
HAB1 B1 for mucin
HIST2H2AA3 histone cluster 2, H2aa3
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HYI hydroxypyruvate isomerase (putative)
IFNA17 interferon, alpha 17
INO80B INO80 complex subunit B
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KDSR 3-ketodihydrosphingosine reductase
KIAA1109 KIAA1109
KIF24 kinesin family member 24
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KLK11 kallikrein-related peptidase 11
LRRC41 leucine rich repeat containing 41
LTBP1 latent transforming growth factor beta binding protein 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAL mal, T-cell differentiation protein
MED25 mediator complex subunit 25
MIOS missing oocyte, meiosis regulator, homolog (Drosophila)
MMP19 matrix metallopeptidase 19
MYO1E myosin IE
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NPR2 natriuretic peptide receptor 2
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
PIGC phosphatidylinositol glycan anchor biosynthesis, class C
PKD1 polycystic kidney disease 1 (autosomal dominant)
PODNL1 podocan-like 1
POU2F2 POU class 2 homeobox 2
POU5F1B POU class 5 homeobox 1B
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
RAB3D RAB3D, member RAS oncogene family
RANBP1 RAN binding protein 1
RASAL2 RAS protein activator like 2
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RB1 retinoblastoma 1
RNF5 ring finger protein 5, E3 ubiquitin protein ligase
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe)
SAFB scaffold attachment factor B
SBNO2 strawberry notch homolog 2 (Drosophila)
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein
SIGLEC7 sialic acid binding Ig-like lectin 7
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SMAD5 SMAD family member 5
SNAPC5 small nuclear RNA activating complex, polypeptide 5, 19kDa
SULT4A1 sulfotransferase family 4A, member 1
TAS2R4 taste receptor, type 2, member 4
TCP10L t-complex 10-like
TCP11L1 t-complex 11, testis-specific-like 1
TMEM212 transmembrane protein 212
TPD52L1 tumor protein D52-like 1
TRIL TLR4 interactor with leucine-rich repeats
VASP vasodilator-stimulated phosphoprotein
VSNL1 visinin-like 1
VWF von Willebrand factor
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF154 zinc finger protein 154
ZNF185 zinc finger protein 185 (LIM domain)

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ACPP acid phosphatase, prostate
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ADTRP androgen-dependent TFPI-regulating protein
AIPL1 aryl hydrocarbon receptor interacting protein-like 1
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARL15 ADP-ribosylation factor-like 15
BIK BCL2-interacting killer (apoptosis-inducing)
C11ORF30 chromosome 11 open reading frame 30
C1ORF56 chromosome 1 open reading frame 56
C22ORF29 chromosome 22 open reading frame 29
CAPN5 calpain 5
CCDC71 coiled-coil domain containing 71
CDK3 cyclin-dependent kinase 3
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CLCN2 chloride channel, voltage-sensitive 2
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CNTN1 contactin 1
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
DGAT1 diacylglycerol O-acyltransferase 1
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
EXOC6B exocyst complex component 6B
FBXO31 F-box protein 31
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FLT4 fms-related tyrosine kinase 4
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GLTSCR1 glioma tumor suppressor candidate region gene 1
GMPPB GDP-mannose pyrophosphorylase B
HRH2 histamine receptor H2
HYAL3 hyaluronoglucosaminidase 3
ICAM5 intercellular adhesion molecule 5, telencephalin
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
KIAA0754 KIAA0754
KIAA1024 KIAA1024
KIF1B kinesin family member 1B
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MANSC1 MANSC domain containing 1
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MCPH1 microcephalin 1
MIR22HG MIR22 host gene
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MXD3 MAX dimerization protein 3
NACA2 nascent polypeptide-associated complex alpha subunit 2
NOL6 nucleolar protein 6 (RNA-associated)
OASL 2'-5'-oligoadenylate synthetase-like
PADI2 peptidyl arginine deiminase, type II
PIPOX pipecolic acid oxidase
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
POLH polymerase (DNA directed), eta
PRKCZ protein kinase C, zeta
PRSS53 protease, serine, 53
RAB17 RAB17, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SCAMP5 secretory carrier membrane protein 5
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC12A9 solute carrier family 12, member 9
SLC35F6 solute carrier family 35, member F6
SPAG7 sperm associated antigen 7
STX17 syntaxin 17
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TCTA T-cell leukemia translocation altered
TCTN2 tectonic family member 2
TIGD6 tigger transposable element derived 6
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast)
TLR4 toll-like receptor 4
TM7SF2 transmembrane 7 superfamily member 2
TMEM209 transmembrane protein 209
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TRAIP TRAF interacting protein
TRDMT1 tRNA aspartic acid methyltransferase 1
TRIM25 tripartite motif containing 25
TRPS1 trichorhinophalangeal syndrome I
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TSC22D4 TSC22 domain family, member 4
TUBA3C tubulin, alpha 3c
USB1 U6 snRNA biogenesis 1
VASH1 vasohibin 1
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
XYLT2 xylosyltransferase II
YPEL1 yippee-like 1 (Drosophila)
YY2 YY2 transcription factor
ZBTB22 zinc finger and BTB domain containing 22
ZFAND3 zinc finger, AN1-type domain 3
ZNF134 zinc finger protein 134
ZNF304 zinc finger protein 304
ZNF428 zinc finger protein 428
ZNF74 zinc finger protein 74