thymus cancer Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description An immune system cancer located_in the thymus. (Human Disease Ontology, DOID_3277)
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Genes

350 genes co-occuring with the disease thymus cancer in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
TTN titin 1.91967
MUSK muscle, skeletal, receptor tyrosine kinase 1.6633
CD5 CD5 molecule 1.59251
DPYSL5 dihydropyrimidinase-like 5 1.53613
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.52776
RYR1 ryanodine receptor 1 (skeletal) 1.49482
CD4 CD4 molecule 1.47857
TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) 1.47769
KCNA4 potassium channel, voltage gated shaker related subfamily A, member 4 1.37512
THY1 Thy-1 cell surface antigen 1.33021
IL2 interleukin 2 1.32978
AKT2 v-akt murine thymoma viral oncogene homolog 2 1.13966
AIRE autoimmune regulator 1.12952
STK16 serine/threonine kinase 16 1.12614
AMPH amphiphysin 1.09209
NOB1 NIN1/RPN12 binding protein 1 homolog (S. cerevisiae) 1.0484
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 1.04293
NMT1 N-myristoyltransferase 1 0.995283
LRP4 low density lipoprotein receptor-related protein 4 0.945354
DPYSL4 dihydropyrimidinase-like 4 0.938704
NMS neuromedin S 0.937874
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 0.920911
TRAC T cell receptor alpha constant 0.89582
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.892129
OMG oligodendrocyte myelin glycoprotein 0.848716
EGFR epidermal growth factor receptor 0.835198
B3GAT1 beta-1,3-glucuronyltransferase 1 0.828229
POMC proopiomelanocortin 0.826999
LDHB lactate dehydrogenase B 0.793361
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein 0.779841
KRT5 keratin 5, type II 0.765127
NKX2-1 NK2 homeobox 1 0.756564
ACHE acetylcholinesterase (Yt blood group) 0.736649
TP53 tumor protein p53 0.733001
HLA-B major histocompatibility complex, class I, B 0.724502
PIGB phosphatidylinositol glycan anchor biosynthesis, class B 0.707961
LGI1 leucine-rich, glioma inactivated 1 0.703134
LCK LCK proto-oncogene, Src family tyrosine kinase 0.694702
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.693499
MNT MAX network transcriptional repressor 0.692697
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 0.677903
MMP11 matrix metallopeptidase 11 0.67551
PNMA2 paraneoplastic Ma antigen 2 0.674713
ZBTB7B zinc finger and BTB domain containing 7B 0.673518
BCHE butyrylcholinesterase 0.668345
CD34 CD34 molecule 0.663578
PTPRC protein tyrosine phosphatase, receptor type, C 0.6608
PDCD7 programmed cell death 7 0.648138
DOK7 docking protein 7 0.644192
SYP synaptophysin 0.635135
PTEN phosphatase and tensin homolog 0.628065
CD99 CD99 molecule 0.626888
CD7 CD7 molecule 0.617877
PAX8 paired box 8 0.611229
MTCH1 mitochondrial carrier 1 0.603811
IL1A interleukin 1, alpha 0.6003
SMAD1 SMAD family member 1 0.596792
DHDH dihydrodiol dehydrogenase (dimeric) 0.596402
MMP10 matrix metallopeptidase 10 0.590948
CD58 CD58 molecule 0.587444
MEN1 multiple endocrine neoplasia I 0.587054
ARHGAP44 Rho GTPase activating protein 44 0.586276
HLA-E major histocompatibility complex, class I, E 0.584719
DSG3 desmoglein 3 0.58433
FOXO1 forkhead box O1 0.583552
FOXN1 forkhead box N1 0.583163
SST somatostatin 0.576939
ENO2 enolase 2 (gamma, neuronal) 0.569552
BRAF B-Raf proto-oncogene, serine/threonine kinase 0.5645
DNTT DNA nucleotidylexotransferase 0.563335
CTLA4 cytotoxic T-lymphocyte-associated protein 4 0.550911
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 0.550134
MAPK3 mitogen-activated protein kinase 3 0.545481
DAP3 death associated protein 3 0.545093
CD79A CD79a molecule, immunoglobulin-associated alpha 0.544318
TG thyroglobulin 0.543155
ZNF185 zinc finger protein 185 (LIM domain) 0.531928
CALCA calcitonin-related polypeptide alpha 0.531154
TRPC3 transient receptor potential cation channel, subfamily C, member 3 0.529994
HRAS Harvey rat sarcoma viral oncogene homolog 0.527676
PPP1R7 protein phosphatase 1, regulatory subunit 7 0.52729
CHGA chromogranin A 0.52536
CNTNAP2 contactin associated protein-like 2 0.524588
TMSB4X thymosin beta 4, X-linked 0.519961
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 0.51919
RAD17 RAD17 homolog (S. pombe) 0.517649
IL5 interleukin 5 0.512264
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle) 0.509576
CD28 CD28 molecule 0.502675
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 0.492359
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.489311
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.482844
INS insulin 0.481705
CD19 CD19 molecule 0.479807
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 0.477151
TRIB3 tribbles pseudokinase 3 0.472225
CAMP cathelicidin antimicrobial peptide 0.469197
NPB neuropeptide B 0.468441
CAPN7 calpain 7 0.464283
CD48 CD48 molecule 0.464283
PRSS16 protease, serine, 16 (thymus) 0.464283
CD69 CD69 molecule 0.463905
IRS2 insulin receptor substrate 2 0.461639
SNED1 sushi, nidogen and EGF-like domains 1 0.449571
HAVCR2 hepatitis A virus cellular receptor 2 0.448817
FNTA farnesyltransferase, CAAX box, alpha 0.446935
CALB2 calbindin 2 0.442042
INSR insulin receptor 0.440162
RGS3 regulator of G-protein signaling 3 0.437154
ALPPL2 alkaline phosphatase, placental-like 2 0.436026
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 0.42589
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 0.420641
VNN2 vanin 2 0.417644
SC5D sterol-C5-desaturase 0.41727
CEMP1 cementum protein 1 0.416521
PPL periplakin 0.413153
LMF1 lipase maturation factor 1 0.412405
SRRM1 serine/arginine repetitive matrix 1 0.40904
ALPP alkaline phosphatase, placental 0.407919
ALPL alkaline phosphatase, liver/bone/kidney 0.407545
TMX1 thioredoxin-related transmembrane protein 1 0.406798
SYT1 synaptotagmin I 0.405678
EVPL envoplakin 0.404184
CD40 CD40 molecule, TNF receptor superfamily member 5 0.403064
MUC15 mucin 15, cell surface associated 0.397843
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.389653
GMFB glia maturation factor, beta 0.388909
LPXN leupaxin 0.386308
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 0.386308
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 0.386308
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) 0.385936
PHYH phytanoyl-CoA 2-hydroxylase 0.385936
SOX1 SRY (sex determining region Y)-box 1 0.385565
IL1B interleukin 1, beta 0.376661
IFNA1 interferon, alpha 1 0.37555
CYS1 cystin 1 0.373698
RAPSN receptor-associated protein of the synapse 0.372587
KCNA6 potassium channel, voltage gated shaker related subfamily A, member 6 0.364824
KRT7 keratin 7, type II 0.363716
MSC musculin 0.362978
AVP arginine vasopressin 0.362978
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 0.362239
PLEK pleckstrin 0.360764
PTPRA protein tyrosine phosphatase, receptor type, A 0.359289
PPP1R3A protein phosphatase 1, regulatory subunit 3A 0.35892
CST7 cystatin F (leukocystatin) 0.356709
CIC capicua transcriptional repressor 0.353763
AKAP4 A kinase (PRKA) anchor protein 4 0.350084
CXCR5 chemokine (C-X-C motif) receptor 5 0.350084
EFNA2 ephrin-A2 0.344574
KRAS Kirsten rat sarcoma viral oncogene homolog 0.343473
IRS1 insulin receptor substrate 1 0.343106
TBC1D4 TBC1 domain family, member 4 0.343106
MDM4 MDM4, p53 regulator 0.340906
ERBB2 erb-b2 receptor tyrosine kinase 2 0.33944
CD8A CD8a molecule 0.338341
CHRNG cholinergic receptor, nicotinic, gamma (muscle) 0.336144
HLA-A major histocompatibility complex, class I, A 0.334315
SLC38A4 solute carrier family 38, member 4 0.333583
JUN jun proto-oncogene 0.332487
GABPB1 GA binding protein transcription factor, beta subunit 1 0.329565
SLC4A3 solute carrier family 4 (anion exchanger), member 3 0.3292
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit 0.325552
IL4 interleukin 4 0.325552
KIF1BP KIF1 binding protein 0.323002
DSG1 desmoglein 1 0.321909
MB myoglobin 0.321545
CD38 CD38 molecule 0.319363
SGK3 serum/glucocorticoid regulated kinase family, member 3 0.315003
EEF1A1P6 eukaryotic translation elongation factor 1 alpha 1 pseudogene 6 0.313189
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 0.310652
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.306672
PTCRA pre T-cell antigen receptor alpha 0.305587
MYL2 myosin, light chain 2, regulatory, cardiac, slow 0.304864
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2 0.301254
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.299452
SYT2 synaptotagmin II 0.299092
NKX6-1 NK6 homeobox 1 0.298731
DNER delta/notch-like EGF repeat containing 0.296571
RND1 Rho family GTPase 1 0.294413
FOXP3 forkhead box P3 0.294053
KRT20 keratin 20, type I 0.290103
DTX1 deltex 1, E3 ubiquitin ligase 0.284728
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 0.28294
MTA2 metastasis associated 1 family, member 2 0.281868
DYNLT1 dynein, light chain, Tctex-type 1 0.280082
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin) 0.276514
BRD4 bromodomain containing 4 0.274376
DPYD dihydropyrimidine dehydrogenase 0.273308
CD70 CD70 molecule 0.27153
ATL2 atlastin GTPase 2 0.27153
STIM1 stromal interaction molecule 1 0.267622
PRKACA protein kinase, cAMP-dependent, catalytic, alpha 0.26514
AQP4 aquaporin 4 0.264431
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.263368
BCL2 B-cell CLL/lymphoma 2 0.261599
GIN1 gypsy retrotransposon integrase 1 0.259124
HAS2 hyaluronan synthase 2 0.257711
UMPS uridine monophosphate synthetase 0.257005
AKT3 v-akt murine thymoma viral oncogene homolog 3 0.254888
MAP3K8 mitogen-activated protein kinase kinase kinase 8 0.253831
TFRC transferrin receptor 0.252774
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.250663
KLRAP1 killer cell lectin-like receptor subfamily A pseudogene 1 0.24715
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like 0.24715
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 0.244696
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2 0.243295
CD247 CD247 molecule 0.242595
DEPTOR DEP domain containing MTOR-interacting protein 0.241895
SALL4 spalt-like transcription factor 4 0.241196
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 0.239101
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit 0.238403
GZMK granzyme K (granzyme 3; tryptase II) 0.23492
CRMP1 collapsin response mediator protein 1 0.233878
PPARG peroxisome proliferator-activated receptor gamma 0.231795
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 0.231448
STPG1 sperm-tail PG-rich repeat containing 1 0.230755
ERBB3 erb-b2 receptor tyrosine kinase 3 0.229716
GNAT3 guanine nucleotide binding protein, alpha transducing 3 0.227297
CD86 CD86 molecule 0.226607
NOTCH1 notch 1 0.225573
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 0.225573
FYN FYN proto-oncogene, Src family tyrosine kinase 0.222822
PTPN12 protein tyrosine phosphatase, non-receptor type 12 0.221793
SPATA21 spermatogenesis associated 21 0.218715
ITCH itchy E3 ubiquitin protein ligase 0.218374
RAD51B RAD51 paralog B 0.217693
OAT ornithine aminotransferase 0.215992
PTPRD protein tyrosine phosphatase, receptor type, D 0.215992
HDLBP high density lipoprotein binding protein 0.214975
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 0.214297
MIR185 microRNA 185 0.209918
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 0.209918
TGFB1 transforming growth factor, beta 1 0.208245
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 0.206913
B2M beta-2-microglobulin 0.205585
EP400 E1A binding protein p400 0.204263
PLVAP plasmalemma vesicle associated protein 0.204263
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) 0.201635
TCHH trichohyalin 0.200982
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 0.198709
IL7R interleukin 7 receptor 0.198709
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 0.198386
PTHLH parathyroid hormone-like hormone 0.19742
CIITA class II, major histocompatibility complex, transactivator 0.196779
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 0.196139
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.19582
CHD4 chromodomain helicase DNA binding protein 4 0.195183
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 0.194232
SRPR signal recognition particle receptor (docking protein) 0.1936
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) 0.192971
CD44 CD44 molecule (Indian blood group) 0.192031
PIGA phosphatidylinositol glycan anchor biosynthesis, class A 0.192031
TXN thioredoxin 0.190786
SLC9A9 solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9 0.18621
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 0.18591
FOSL1 FOS-like antigen 1 0.184128
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.184128
PTGES2 prostaglandin E synthase 2 0.182086
BIN3 bridging integrator 3 0.182086
PTH parathyroid hormone 0.181222
TNF tumor necrosis factor 0.179239
LY75 lymphocyte antigen 75 0.178403
CD1A CD1a molecule 0.176485
SGK1 serum/glucocorticoid regulated kinase 1 0.172291
KRT84 keratin 84, type II 0.172291
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 0.169812
PIR pirin (iron-binding nuclear protein) 0.168854
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 0.168617
RET ret proto-oncogene 0.168617
GIPC1 GIPC PDZ domain containing family, member 1 0.166095
EPOR erythropoietin receptor 0.165655
CHRND cholinergic receptor, nicotinic, delta (muscle) 0.165655
LMO1 LIM domain only 1 (rhombotin 1) 0.165217
PPP1R9B protein phosphatase 1, regulatory subunit 9B 0.164359
PCNA proliferating cell nuclear antigen 0.163938
GCM2 glial cells missing homolog 2 (Drosophila) 0.163729
TLR4 toll-like receptor 4 0.162505
FOS FBJ murine osteosarcoma viral oncogene homolog 0.162306
FBXO32 F-box protein 32 0.162109
CORT cortistatin 0.161523
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 0.161331
INHBA inhibin, beta A 0.160021
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 0.159302
GPR17 G protein-coupled receptor 17 0.158434
RRAS related RAS viral (r-ras) oncogene homolog 0.158097
OPCML opioid binding protein/cell adhesion molecule-like 0.157602
CD6 CD6 molecule 0.157602
MAML2 mastermind-like 2 (Drosophila) 0.140501
TXNL1 thioredoxin-like 1 0.140459
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.138157
CTNND1 catenin (cadherin-associated protein), delta 1 0.135198
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1 0.130548
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 0.128778
ACOT13 acyl-CoA thioesterase 13 0.12862
IVL involucrin 0.125751
KRT14 keratin 14, type I 0.124629
HSD17B1P1 hydroxysteroid (17-beta) dehydrogenase 1 pseudogene 1 0.122193
STS steroid sulfatase (microsomal), isozyme S 0.120825
NAPSA napsin A aspartic peptidase 0.119996
CDX2 caudal type homeobox 2 0.119819
PDPN podoplanin 0.118475
KITLG KIT ligand 0.113493
S100A9 S100 calcium binding protein A9 0.110294
TIMP2 TIMP metallopeptidase inhibitor 2 0.102921
FSCN3 fascin actin-bundling protein 3, testicular 0.102902
FSCN2 fascin actin-bundling protein 2, retinal 0.101573
VCAM1 vascular cell adhesion molecule 1 0.099991
ESR1 estrogen receptor 1 0.09965
FSCN1 fascin actin-bundling protein 1 0.096409
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.093723
NGFR nerve growth factor receptor 0.091159
MPG N-methylpurine-DNA glycosylase 0.089169
KRT13 keratin 13, type I 0.087389
MMP7 matrix metallopeptidase 7 0.087081
KRT19 keratin 19, type I 0.087057
CD72 CD72 molecule 0.086131
NUTM1 NUT midline carcinoma, family member 1 0.084834
MSLN mesothelin 0.084713
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 0.084152
IGF1R insulin-like growth factor 1 receptor 0.081473
PGR progesterone receptor 0.080999
EREG epiregulin 0.078816
AK6 adenylate kinase 6 0.077698
NGF nerve growth factor (beta polypeptide) 0.076524
IGLV2-8 immunoglobulin lambda variable 2-8 0.073376
HDAC4 histone deacetylase 4 0.073141
GPR182 G protein-coupled receptor 182 0.072907
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.072647
MUC2 mucin 2, oligomeric mucus/gel-forming 0.071158
BIRC5 baculoviral IAP repeat containing 5 0.070241
INHA inhibin, alpha 0.06803
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 0.067555
ESR2 estrogen receptor 2 (ER beta) 0.066604
ASXL1 additional sex combs like transcriptional regulator 1 0.066233
CD68 CD68 molecule 0.066207
DAPK1 death-associated protein kinase 1 0.066154
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.065784
ZBTB7A zinc finger and BTB domain containing 7A 0.065757
IL2RA interleukin 2 receptor, alpha 0.065678
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2 0.06552
CREB1 cAMP responsive element binding protein 1 0.065175
SPRY2 sprouty homolog 2 (Drosophila) 0.065122
KARS lysyl-tRNA synthetase 0.065069
DSP desmoplakin 0.065016
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3 0.064989
LAMP2 lysosomal-associated membrane protein 2 0.06483
SPN sialophorin 0.064804
PPARD peroxisome proliferator-activated receptor delta 0.064592
TICAM2 toll-like receptor adaptor molecule 2 0.064512