thoracic benign neoplasm Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description An organ system benign neoplam that is located_in the thoracic cavity. (Human Disease Ontology, DOID_0060097)
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Genes

189 genes co-occuring with the disease thoracic benign neoplasm in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
PGR progesterone receptor 1.46759
ESR1 estrogen receptor 1 1.31974
ERBB2 erb-b2 receptor tyrosine kinase 2 1.16992
CD34 CD34 molecule 1.00077
TP53 tumor protein p53 0.978006
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 0.953273
SYNJ2BP synaptojanin 2 binding protein 0.836017
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit 0.832738
KRT15 keratin 15, type I 0.788033
PCNA proliferating cell nuclear antigen 0.765127
KRT14 keratin 14, type I 0.752085
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 0.726929
KRT8 keratin 8, type II 0.725716
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 0.718443
MKI67 marker of proliferation Ki-67 0.69751
KDM4A lysine (K)-specific demethylase 4A 0.672324
PIP prolactin-induced protein 0.672324
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 0.665166
MED19 mediator complex subunit 19 0.632777
KRT31 keratin 31, type I 0.610057
F8 coagulation factor VIII, procoagulant component 0.577327
ESR2 estrogen receptor 2 (ER beta) 0.577327
DOCK4 dedicator of cytokinesis 4 0.576161
ACVR1C activin A receptor, type IC 0.566443
KRT7 keratin 7, type II 0.565277
KRT5 keratin 5, type II 0.558285
AR androgen receptor 0.55712
RHEB Ras homolog enriched in brain 0.555956
RAB27B RAB27B, member RAS oncogene family 0.554015
PRL prolactin 0.554015
USP22 ubiquitin specific peptidase 22 0.552851
HIC1 hypermethylated in cancer 1 0.548971
EGFR epidermal growth factor receptor 0.529608
ST14 suppression of tumorigenicity 14 (colon carcinoma) 0.52343
GREM2 gremlin 2, DAN family BMP antagonist 0.50689
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5 0.498849
SNCG synuclein, gamma (breast cancer-specific protein 1) 0.49274
EFNA3 ephrin-A3 0.490072
PZP pregnancy-zone protein 0.482844
LAMA5 laminin, alpha 5 0.472982
WEE1 WEE1 G2 checkpoint kinase 0.46466
CLDN6 claudin 6 0.462772
FSTL3 follistatin-like 3 (secreted glycoprotein) 0.444676
PELP1 proline, glutamate and leucine rich protein 1 0.441666
MMP2 matrix metallopeptidase 2 0.43227
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2 0.42739
A1BG alpha-1-B glycoprotein 0.425514
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4 0.42214
PLVAP plasmalemma vesicle associated protein 0.417644
CALR calreticulin 0.413901
NMU neuromedin U 0.411283
MIB1 mindbomb E3 ubiquitin protein ligase 1 0.410909
HDAC1 histone deacetylase 1 0.410161
AMHR2 anti-Mullerian hormone receptor, type II 0.407919
VASH1 vasohibin 1 0.403811
WIBG within bgcn homolog (Drosophila) 0.398589
GRIK4 glutamate receptor, ionotropic, kainate 4 0.396725
DIO1 deiodinase, iodothyronine, type I 0.395235
MFGE8 milk fat globule-EGF factor 8 protein 0.385565
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.381852
RARB retinoic acid receptor, beta 0.369997
DDX53 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 0.368149
FAP fibroblast activation protein, alpha 0.367779
CSH1 chorionic somatomammotropin hormone 1 (placental lactogen) 0.360764
KDR kinase insert domain receptor 0.359289
DIRAS3 DIRAS family, GTP-binding RAS-like 3 0.359289
ACTA1 actin, alpha 1, skeletal muscle 0.353395
FST follistatin 0.353027
PARVA parvin, alpha 0.348981
HIST1H4F histone cluster 1, H4f 0.347879
HIST2H4B histone cluster 2, H4b 0.347879
HIST1H4K histone cluster 1, H4k 0.347879
HIST1H4H histone cluster 1, H4h 0.347879
HIST1H4C histone cluster 1, H4c 0.347879
HIST1H4A histone cluster 1, H4a 0.347879
HIST1H4B histone cluster 1, H4b 0.347879
HIST1H4E histone cluster 1, H4e 0.347879
HIST1H4J histone cluster 1, H4j 0.347879
HIST1H4I histone cluster 1, H4i 0.347879
HIST1H4D histone cluster 1, H4d 0.347879
HIST2H4A histone cluster 2, H4a 0.347144
HIST1H4L histone cluster 1, H4l 0.345675
HIST4H4 histone cluster 4, H4 0.345308
CSH2 chorionic somatomammotropin hormone 2 0.341272
MOGS mannosyl-oligosaccharide glucosidase 0.33944
AOC3 amine oxidase, copper containing 3 0.324823
RUNX3 runt-related transcription factor 3 0.317545
FANCB Fanconi anemia, complementation group B 0.299452
BRCA2 breast cancer 2, early onset 0.296571
MYC v-myc avian myelocytomatosis viral oncogene homolog 0.290103
SEMG1 semenogelin I 0.28616
HRG histidine-rich glycoprotein 0.281868
MATN1 matrilin 1, cartilage matrix protein 0.28151
IFITM1 interferon induced transmembrane protein 1 0.279367
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha 0.273308
FLAD1 flavin adenine dinucleotide synthetase 1 0.272241
NEK8 NIMA-related kinase 8 0.272241
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) 0.268332
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme 0.264785
CD44 CD44 molecule (Indian blood group) 0.263368
TPM2 tropomyosin 2 (beta) 0.263014
RAP1A RAP1A, member of RAS oncogene family 0.262306
FASLG Fas ligand (TNF superfamily, member 6) 0.255946
GHR growth hormone receptor 0.253479
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.253479
CTSD cathepsin D 0.251015
TP73 tumor protein p73 0.250311
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.249257
RBP1 retinol binding protein 1, cellular 0.247852
AGO2 argonaute RISC catalytic component 2 0.246448
CHMP2A charged multivesicular body protein 2A 0.246448
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 0.237706
HBA1 hemoglobin, alpha 1 0.237357
PPT1 palmitoyl-protein thioesterase 1 0.225573
KITLG KIT ligand 0.223509
FGF1 fibroblast growth factor 1 (acidic) 0.220424
MED12 mediator complex subunit 12 0.219398
PLG plasminogen 0.218715
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 0.218374
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1 0.217693
HBA2 hemoglobin, alpha 2 0.217352
S100A10 S100 calcium binding protein A10 0.216332
CFL1 cofilin 1 (non-muscle) 0.214297
ADGRV1 adhesion G protein-coupled receptor V1 0.20229
TGFA transforming growth factor, alpha 0.200982
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme 0.197742
AOC2 amine oxidase, copper containing 2 (retina-specific) 0.197099
BRCA1 breast cancer 1, early onset 0.196459
CCND2 cyclin D2 0.193915
G6PD glucose-6-phosphate dehydrogenase 0.187719
SYK spleen tyrosine kinase 0.18651
HMGA2 high mobility group AT-hook 2 0.183248
ALPPL2 alkaline phosphatase, placental-like 2 0.182086
ALPP alkaline phosphatase, placental 0.181798
ALPL alkaline phosphatase, liver/bone/kidney 0.181222
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.180937
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 0.178126
TGFB1 transforming growth factor, beta 1 0.178126
ACPP acid phosphatase, prostate 0.175947
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 0.172544
CCND1 cyclin D1 0.172291
TIMP3 TIMP metallopeptidase inhibitor 3 0.172291
MUC1 mucin 1, cell surface associated 0.170054
SPP1 secreted phosphoprotein 1 0.169091
NGFR nerve growth factor receptor 0.167224
FN1 fibronectin 1 0.164359
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1 0.164149
TPM1 tropomyosin 1 (alpha) 0.163111
CXXC1 CXXC finger protein 1 0.15948
HK1 hexokinase 1 0.158951
MIR21 microRNA 21 0.158605
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.158266
VEGFA vascular endothelial growth factor A 0.158266
CD68 CD68 molecule 0.139906
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog 0.137451
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like 0.134322
SRY sex determining region Y 0.132681
PTEN phosphatase and tensin homolog 0.128474
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 0.113945
TRH thyrotropin-releasing hormone 0.099488
SYP synaptophysin 0.097452
CMA1 chymase 1, mast cell 0.096608
LAX1 lymphocyte transmembrane adaptor 1 0.096247
CALD1 caldesmon 1 0.095833
IFNG interferon, gamma 0.087149
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae) 0.086037
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.085085
LALBA lactalbumin, alpha- 0.084546
H2AFX H2A histone family, member X 0.081075
DES desmin 0.077079
WT1 Wilms tumor 1 0.07484
CDKN2A cyclin-dependent kinase inhibitor 2A 0.073479
KLK3 kallikrein-related peptidase 3 0.067286
POMC proopiomelanocortin 0.066524
CHGA chromogranin A 0.0662
CD72 CD72 molecule 0.064924
SRSF1 serine/arginine-rich splicing factor 1 0.064466
FGFR1 fibroblast growth factor receptor 1 0.064047
PLAT plasminogen activator, tissue 0.061986
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.061547
IGF2 insulin-like growth factor 2 0.060136
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 0.057892
EFNB2 ephrin-B2 0.057664
AHR aryl hydrocarbon receptor 0.05757
GFAP glial fibrillary acidic protein 0.057456
MGAT4C MGAT4 family, member C 0.057418
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2 0.057266
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.057247
PRRC2A proline-rich coiled-coil 2A 0.057228