thoracic aortic aneurysm Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description An aortic aneurysm that is located_in the thoracic aorta. (Human Disease Ontology, DOID_14004)
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Genes

71 genes co-occuring with the disease thoracic aortic aneurysm in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
ACTA2 actin, alpha 2, smooth muscle, aorta 1.94736
FBN1 fibrillin 1 1.93984
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 1.44957
TGFBR1 transforming growth factor, beta receptor 1 1.43113
MYH11 myosin, heavy chain 11, smooth muscle 1.27519
SMAD3 SMAD family member 3 1.24341
TIMP4 TIMP metallopeptidase inhibitor 4 1.19575
MMP2 matrix metallopeptidase 2 1.10132
COL3A1 collagen, type III, alpha 1 1.07698
MMP9 matrix metallopeptidase 9 0.979689
CMC4 C-x(9)-C motif containing 4 0.975482
AAAS achalasia, adrenocortical insufficiency, alacrimia 0.927105
TGFB2 transforming growth factor, beta 2 0.84585
GRHL1 grainyhead-like 1 (Drosophila) 0.820437
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 0.725311
S100A12 S100 calcium binding protein A12 0.682294
LTBP1 latent transforming growth factor beta binding protein 1 0.644586
MMP1 matrix metallopeptidase 1 0.635921
TIMP1 TIMP metallopeptidase inhibitor 1 0.624143
DAB2IP DAB2 interacting protein 0.609276
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta) 0.603811
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2 0.60303
NTM neurotrimin 0.591337
MYLK myosin light chain kinase 0.587444
MMP14 matrix metallopeptidase 14 (membrane-inserted) 0.560227
ELN elastin 0.548195
TIMP3 TIMP metallopeptidase inhibitor 3 0.531154
TIMP2 TIMP metallopeptidase inhibitor 2 0.523045
MMP3 matrix metallopeptidase 3 0.521502
SMTN smoothelin 0.521502
TNXB tenascin XB 0.507657
LHB luteinizing hormone beta polypeptide 0.488169
PCYT1A phosphate cytidylyltransferase 1, choline, alpha 0.471846
BAD BCL2-associated agonist of cell death 0.471468
TNXA tenascin XA (pseudogene) 0.466172
PDHX pyruvate dehydrogenase complex, component X 0.465038
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 0.446935
MMP12 matrix metallopeptidase 12 0.43941
THBS2 thrombospondin 2 0.415024
AGPS alkylglycerone phosphate synthase 0.412779
SORT1 sortilin 1 0.396353
ACE angiotensin I converting enzyme 0.393001
MMP8 matrix metallopeptidase 8 0.381481
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3 0.380739
CRP C-reactive protein, pentraxin-related 0.371107
SMAD4 SMAD family member 4 0.369628
DLL4 delta-like 4 (Drosophila) 0.364085
TXNL4B thioredoxin-like 4B 0.343473
COL1A2 collagen, type I, alpha 2 0.331025
FBXL20 F-box and leucine-rich repeat protein 20 0.328834
ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif, 4 0.30631
AGER advanced glycosylation end product-specific receptor 0.289744
MMP13 matrix metallopeptidase 13 0.284013
BMPER BMP binding endothelial regulator 0.284013
MMP25 matrix metallopeptidase 25 0.275801
MFGE8 milk fat globule-EGF factor 8 protein 0.275801
CTGF connective tissue growth factor 0.273308
LCK LCK proto-oncogene, Src family tyrosine kinase 0.260538
FBN2 fibrillin 2 0.252774
NOTCH1 notch 1 0.250311
ACVRL1 activin A receptor type II-like 1 0.239799
MMP11 matrix metallopeptidase 11 0.236312
SDF4 stromal cell derived factor 4 0.215992
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 0.214297
VCAN versican 0.211597
ADAM10 ADAM metallopeptidase domain 10 0.194232
MMP7 matrix metallopeptidase 7 0.193285
ADAM17 ADAM metallopeptidase domain 17 0.182375
HSPA8 heat shock 70kDa protein 8 0.174093
S100A4 S100 calcium binding protein A4 0.165655
AGTR1 angiotensin II receptor, type 1 0.161523