thioperamide-4675 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the thioperamide-4675 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
ADAM12 ADAM metallopeptidase domain 12
ADGRB2 adhesion G protein-coupled receptor B2
AKAP8L A kinase (PRKA) anchor protein 8-like
ALOX5 arachidonate 5-lipoxygenase
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ASPHD1 aspartate beta-hydroxylase domain containing 1
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
BTG2 BTG family, member 2
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CADM3 cell adhesion molecule 3
CADM4 cell adhesion molecule 4
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CCL27 chemokine (C-C motif) ligand 27
CDC42 cell division cycle 42
CDK19 cyclin-dependent kinase 19
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene
COL4A6 collagen, type IV, alpha 6
CSF1R colony stimulating factor 1 receptor
CXCR4 chemokine (C-X-C motif) receptor 4
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DGKA diacylglycerol kinase, alpha 80kDa
DPYSL4 dihydropyrimidinase-like 4
DRP2 dystrophin related protein 2
DSC1 desmocollin 1
ESRRG estrogen-related receptor gamma
FAXDC2 fatty acid hydroxylase domain containing 2
FRS3 fibroblast growth factor receptor substrate 3
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GADD45G growth arrest and DNA-damage-inducible, gamma
GAS7 growth arrest-specific 7
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GJA4 gap junction protein, alpha 4, 37kDa
GMPR guanosine monophosphate reductase
GOSR2 golgi SNAP receptor complex member 2
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
IL6 interleukin 6
INO80D INO80 complex subunit D
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
INSR insulin receptor
IQCC IQ motif containing C
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KIAA0040 KIAA0040
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MAP3K13 mitogen-activated protein kinase kinase kinase 13
MEGF6 multiple EGF-like-domains 6
MILR1 mast cell immunoglobulin-like receptor 1
NFRKB nuclear factor related to kappaB binding protein
NIPAL2 NIPA-like domain containing 2
NOL4 nucleolar protein 4
NPY6R neuropeptide Y receptor Y6 (pseudogene)
NR5A2 nuclear receptor subfamily 5, group A, member 2
NUP54 nucleoporin 54kDa
ONECUT2 one cut homeobox 2
P2RY13 purinergic receptor P2Y, G-protein coupled, 13
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PBX1 pre-B-cell leukemia homeobox 1
PCDH11Y protocadherin 11 Y-linked
PHLDB1 pleckstrin homology-like domain, family B, member 1
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLXNB3 plexin B3
PNMAL1 paraneoplastic Ma antigen family-like 1
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPP1R37 protein phosphatase 1, regulatory subunit 37
PRDM14 PR domain containing 14
RAB31 RAB31, member RAS oncogene family
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RHO rhodopsin
RIN3 Ras and Rab interactor 3
RPL23AP32 ribosomal protein L23a pseudogene 32
RUNDC3A RUN domain containing 3A
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SOS2 son of sevenless homolog 2 (Drosophila)
STAT2 signal transducer and activator of transcription 2, 113kDa
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
STX7 syntaxin 7
SYMPK symplekin
TBCD tubulin folding cofactor D
TBL2 transducin (beta)-like 2
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFA transforming growth factor, alpha
TM4SF5 transmembrane 4 L six family member 5
TMPRSS4 transmembrane protease, serine 4
TRIM29 tripartite motif containing 29
TTLL4 tubulin tyrosine ligase-like family member 4
TTN titin
TUBA3C tubulin, alpha 3c
TUBB1 tubulin, beta 1 class VI
XYLB xylulokinase homolog (H. influenzae)
ZHX3 zinc fingers and homeoboxes 3
ZNF24 zinc finger protein 24
ZNF484 zinc finger protein 484
ZXDB zinc finger, X-linked, duplicated B

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
AATK apoptosis-associated tyrosine kinase
ADAM2 ADAM metallopeptidase domain 2
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
BATF3 basic leucine zipper transcription factor, ATF-like 3
C5ORF45 chromosome 5 open reading frame 45
CD101 CD101 molecule
CD68 CD68 molecule
CELA2A chymotrypsin-like elastase family, member 2A
CFAP45 cilia and flagella associated protein 45
CISH cytokine inducible SH2-containing protein
CLDN1 claudin 1
CLDN15 claudin 15
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CRISP2 cysteine-rich secretory protein 2
CRLF1 cytokine receptor-like factor 1
CRYGC crystallin, gamma C
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
CYSLTR1 cysteinyl leukotriene receptor 1
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DMTN dematin actin binding protein
DUSP8 dual specificity phosphatase 8
EFNA3 ephrin-A3
EN2 engrailed homeobox 2
EPYC epiphycan
FAM110B family with sequence similarity 110, member B
FAM118A family with sequence similarity 118, member A
FRMPD1 FERM and PDZ domain containing 1
GID4 GID complex subunit 4
GPNMB glycoprotein (transmembrane) nmb
GPR1 G protein-coupled receptor 1
GSTCD glutathione S-transferase, C-terminal domain containing
HAMP hepcidin antimicrobial peptide
HIRA histone cell cycle regulator
HIST1H1E histone cluster 1, H1e
HIST1H4C histone cluster 1, H4c
IFI6 interferon, alpha-inducible protein 6
IGFBP1 insulin-like growth factor binding protein 1
IL32 interleukin 32
IRF2BP1 interferon regulatory factor 2 binding protein 1
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KPTN kaptin (actin binding protein)
LMO7 LIM domain 7
LNPEP leucyl/cystinyl aminopeptidase
LRRK1 leucine-rich repeat kinase 1
LY6D lymphocyte antigen 6 complex, locus D
MAGEF1 melanoma antigen family F1
MAP3K7CL MAP3K7 C-terminal like
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MRPL52 mitochondrial ribosomal protein L52
MYOZ1 myozenin 1
NEUROD1 neuronal differentiation 1
NOL12 nucleolar protein 12
NYNRIN NYN domain and retroviral integrase containing
OCA2 oculocutaneous albinism II
OLFM4 olfactomedin 4
OR1G1 olfactory receptor, family 1, subfamily G, member 1
OSR2 odd-skipped related transciption factor 2
PACS1 phosphofurin acidic cluster sorting protein 1
PDE12 phosphodiesterase 12
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
POM121 POM121 transmembrane nucleoporin
PRKG2 protein kinase, cGMP-dependent, type II
PRM2 protamine 2
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
REM1 RAS (RAD and GEM)-like GTP-binding 1
RFPL1S RFPL1 antisense RNA 1
RGS17 regulator of G-protein signaling 17
RNF126P1 ring finger protein 126 pseudogene 1
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
SCN1B sodium channel, voltage gated, type I beta subunit
SCN9A sodium channel, voltage gated, type IX alpha subunit
SHROOM2 shroom family member 2
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SPATA1 spermatogenesis associated 1
SPINK1 serine peptidase inhibitor, Kazal type 1
STAG3 stromal antigen 3
STAG3L4 stromal antigen 3-like 4 (pseudogene)
SYNGR3 synaptogyrin 3
TCEAL2 transcription elongation factor A (SII)-like 2
TGFBI transforming growth factor, beta-induced, 68kDa
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TIGD6 tigger transposable element derived 6
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TM6SF1 transmembrane 6 superfamily member 1
TMEM212 transmembrane protein 212
TRIM25 tripartite motif containing 25
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TSNAXIP1 translin-associated factor X interacting protein 1
TTF2 transcription termination factor, RNA polymerase II
TTLL1 tubulin tyrosine ligase-like family member 1
ZNF141 zinc finger protein 141
ZNF205 zinc finger protein 205
ZNF219 zinc finger protein 219
ZNF41 zinc finger protein 41
ZNF442 zinc finger protein 442
ZNF480 zinc finger protein 480