thioperamide-3392 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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196 genes differentially expressed following the thioperamide-3392 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ACSL5 acyl-CoA synthetase long-chain family member 5
ACTN1 actinin, alpha 1
ADAM22 ADAM metallopeptidase domain 22
ADCY2 adenylate cyclase 2 (brain)
AMPD3 adenosine monophosphate deaminase 3
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATF3 activating transcription factor 3
ATP10B ATPase, class V, type 10B
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BCL6 B-cell CLL/lymphoma 6
C10ORF12 chromosome 10 open reading frame 12
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CCDC40 coiled-coil domain containing 40
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEP162 centrosomal protein 162kDa
CERS4 ceramide synthase 4
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
COL13A1 collagen, type XIII, alpha 1
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CRTC1 CREB regulated transcription coactivator 1
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
DOCK3 dedicator of cytokinesis 3
DST dystonin
EGR1 early growth response 1
ERAP1 endoplasmic reticulum aminopeptidase 1
ERCC2 excision repair cross-complementation group 2
ETV2 ets variant 2
FAM168A family with sequence similarity 168, member A
FGA fibrinogen alpha chain
FOSL2 FOS-like antigen 2
FRMD1 FERM domain containing 1
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)
GREB1L growth regulation by estrogen in breast cancer-like
GRM4 glutamate receptor, metabotropic 4
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HFE hemochromatosis
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
JPH3 junctophilin 3
KAZN kazrin, periplakin interacting protein
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KLHL35 kelch-like family member 35
LEFTY1 left-right determination factor 1
LENEP lens epithelial protein
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MARK4 MAP/microtubule affinity-regulating kinase 4
MUC5B mucin 5B, oligomeric mucus/gel-forming
N4BP2L1 NEDD4 binding protein 2-like 1
NF2 neurofibromin 2 (merlin)
NR4A1 nuclear receptor subfamily 4, group A, member 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OSBPL2 oxysterol binding protein-like 2
PAPPA2 pappalysin 2
PDE4DIP phosphodiesterase 4D interacting protein
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
POFUT1 protein O-fucosyltransferase 1
PRKD3 protein kinase D3
PRMT2 protein arginine methyltransferase 2
RAB40C RAB40C, member RAS oncogene family
RPS4Y1 ribosomal protein S4, Y-linked 1
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe)
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SALL1 spalt-like transcription factor 1
SETD1B SET domain containing 1B
SFPQ splicing factor proline/glutamine-rich
SH2D3A SH2 domain containing 3A
SH3GL3 SH3-domain GRB2-like 3
SKIL SKI-like proto-oncogene
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
SSTR4 somatostatin receptor 4
STS steroid sulfatase (microsomal), isozyme S
SYN2 synapsin II
SZT2 seizure threshold 2 homolog (mouse)
TGM2 transglutaminase 2
TLE3 transducin-like enhancer of split 3
TMCC2 transmembrane and coiled-coil domain family 2
TPP1 tripeptidyl peptidase I
TREM2 triggering receptor expressed on myeloid cells 2
TRPC4 transient receptor potential cation channel, subfamily C, member 4
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TTC33 tetratricopeptide repeat domain 33
TTC39A tetratricopeptide repeat domain 39A
TXNIP thioredoxin interacting protein
UBA7 ubiquitin-like modifier activating enzyme 7
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
WNT10B wingless-type MMTV integration site family, member 10B
YY2 YY2 transcription factor
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
ACTL8 actin-like 8
ADCK4 aarF domain containing kinase 4
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
BFSP1 beaded filament structural protein 1, filensin
BLNK B-cell linker
C14ORF79 chromosome 14 open reading frame 79
C5 complement component 5
CAMK4 calcium/calmodulin-dependent protein kinase IV
CCDC132 coiled-coil domain containing 132
CCDC134 coiled-coil domain containing 134
CCNO cyclin O
CD34 CD34 molecule
CD83 CD83 molecule
CDK6 cyclin-dependent kinase 6
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CHM choroideremia (Rab escort protein 1)
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CLDN9 claudin 9
COPZ2 coatomer protein complex, subunit zeta 2
CORO7 coronin 7
CRIP1 cysteine-rich protein 1 (intestinal)
CTRL chymotrypsin-like
DENND5B DENN/MADD domain containing 5B
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
ETAA1 Ewing tumor-associated antigen 1
ETV6 ets variant 6
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FGF23 fibroblast growth factor 23
FSCN3 fascin actin-bundling protein 3, testicular
GAST gastrin
GJA8 gap junction protein, alpha 8, 50kDa
GMPR guanosine monophosphate reductase
GPATCH2L G patch domain containing 2-like
GPR143 G protein-coupled receptor 143
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HIST1H4A histone cluster 1, H4a
HLA-DMB major histocompatibility complex, class II, DM beta
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HMOX1 heme oxygenase 1
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
INHA inhibin, alpha
IQCG IQ motif containing G
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
KIAA0355 KIAA0355
KRT9 keratin 9, type I
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LINC01587 long intergenic non-protein coding RNA 1587
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LOC100131532 uncharacterized LOC100131532
LOC390998 ribosomal protein L10 pseudogene
LRRC15 leucine rich repeat containing 15
LYRM9 LYR motif containing 9
MAGEB2 melanoma antigen family B2
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MATK megakaryocyte-associated tyrosine kinase
MEFV Mediterranean fever
MFAP2 microfibrillar-associated protein 2
MLLT4-AS1 MLLT4 antisense RNA 1 (head to head)
MOCS3 molybdenum cofactor synthesis 3
MTL5 metallothionein-like 5, testis-specific (tesmin)
MUC3A mucin 3A, cell surface associated
NACA2 nascent polypeptide-associated complex alpha subunit 2
NKX3-2 NK3 homeobox 2
NLRX1 NLR family member X1
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
OCLM oculomedin
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDIA3 protein disulfide isomerase family A, member 3
PICK1 protein interacting with PRKCA 1
POM121L2 POM121 transmembrane nucleoporin-like 2
PSCA prostate stem cell antigen
RND1 Rho family GTPase 1
SAYSD1 SAYSVFN motif domain containing 1
SCN10A sodium channel, voltage gated, type X alpha subunit
SDS serine dehydratase
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SERGEF secretion regulating guanine nucleotide exchange factor
SLC12A9 solute carrier family 12, member 9
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SPEG SPEG complex locus
SRPX sushi-repeat containing protein, X-linked
TBC1D2 TBC1 domain family, member 2
THSD4 thrombospondin, type I, domain containing 4
TM4SF4 transmembrane 4 L six family member 4
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18
TNS2 tensin 2
TOP3B topoisomerase (DNA) III beta
TUBBP5 tubulin, beta pseudogene 5
WDR78 WD repeat domain 78
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF137P zinc finger protein 137, pseudogene
ZNF557 zinc finger protein 557
ZNF668 zinc finger protein 668