thioguanosine-6643 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the thioguanosine-6643 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ACVR1B activin A receptor, type IB
ADAM22 ADAM metallopeptidase domain 22
ADAM3A ADAM metallopeptidase domain 3A (pseudogene)
ADGRE2 adhesion G protein-coupled receptor E2
AHSG alpha-2-HS-glycoprotein
ANGEL2 angel homolog 2 (Drosophila)
ANGPT2 angiopoietin 2
APOLD1 apolipoprotein L domain containing 1
ARHGAP28 Rho GTPase activating protein 28
ARPIN actin-related protein 2/3 complex inhibitor
ASPHD1 aspartate beta-hydroxylase domain containing 1
BLZF1 basic leucine zipper nuclear factor 1
BMP8A bone morphogenetic protein 8a
BTBD18 BTB (POZ) domain containing 18
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C15ORF39 chromosome 15 open reading frame 39
CACNB4 calcium channel, voltage-dependent, beta 4 subunit
CCDC170 coiled-coil domain containing 170
CCL23 chemokine (C-C motif) ligand 23
CDH10 cadherin 10, type 2 (T2-cadherin)
CEL carboxyl ester lipase
CFHR4 complement factor H-related 4
CGA glycoprotein hormones, alpha polypeptide
CLEC4A C-type lectin domain family 4, member A
CTNS cystinosin, lysosomal cystine transporter
CYP2U1 cytochrome P450, family 2, subfamily U, polypeptide 1
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
ELN elastin
ENPEP glutamyl aminopeptidase (aminopeptidase A)
FAM162A family with sequence similarity 162, member A
FAXDC2 fatty acid hydroxylase domain containing 2
FGF18 fibroblast growth factor 18
FGF3 fibroblast growth factor 3
FLOT1 flotillin 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FRMD4B FERM domain containing 4B
FRZB frizzled-related protein
GFER growth factor, augmenter of liver regeneration
GUCA1B guanylate cyclase activator 1B (retina)
HOXD10 homeobox D10
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
IFNA2 interferon, alpha 2
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
KLF13 Kruppel-like factor 13
KLHL20 kelch-like family member 20
KRT23 keratin 23, type I
LDHC lactate dehydrogenase C
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LINS lines homolog (Drosophila)
LOC157562 uncharacterized LOC157562
LOC1720 dihydrofolate reductase pseudogene
LSAMP limbic system-associated membrane protein
N4BP2L2 NEDD4 binding protein 2-like 2
NCAM1 neural cell adhesion molecule 1
NCR2 natural cytotoxicity triggering receptor 2
NOVA2 neuro-oncological ventral antigen 2
NUP88 nucleoporin 88kDa
ORC5 origin recognition complex, subunit 5
PALM paralemmin
PDZK1 PDZ domain containing 1
PKD2L2 polycystic kidney disease 2-like 2
PLD1 phospholipase D1, phosphatidylcholine-specific
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
PTGER3 prostaglandin E receptor 3 (subtype EP3)
QSER1 glutamine and serine rich 1
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic)
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1
RBM34 RNA binding motif protein 34
RBM48 RNA binding motif protein 48
RGS12 regulator of G-protein signaling 12
RIN3 Ras and Rab interactor 3
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RND1 Rho family GTPase 1
RPL10L ribosomal protein L10-like
RUNX1 runt-related transcription factor 1
SBNO1 strawberry notch homolog 1 (Drosophila)
SCN5A sodium channel, voltage gated, type V alpha subunit
SSX1 synovial sarcoma, X breakpoint 1
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae)
TNP2 transition protein 2 (during histone to protamine replacement)
TRIM49 tripartite motif containing 49
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae)
TRPC4 transient receptor potential cation channel, subfamily C, member 4
UCN urocortin
ZFX zinc finger protein, X-linked
ZNF3 zinc finger protein 3
ZNF350 zinc finger protein 350
ZNF440 zinc finger protein 440
ZNF613 zinc finger protein 613

decreased expression

Symbol Name
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
ACSL4 acyl-CoA synthetase long-chain family member 4
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADRB2 adrenoceptor beta 2, surface
AHCTF1 AT hook containing transcription factor 1
ALPK1 alpha-kinase 1
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ARRB2 arrestin, beta 2
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BAZ1A bromodomain adjacent to zinc finger domain, 1A
BCL2L2 BCL2-like 2
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
C10ORF88 chromosome 10 open reading frame 88
C3 complement component 3
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CDC73 cell division cycle 73
CLDN4 claudin 4
CLDN8 claudin 8
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DCAF4 DDB1 and CUL4 associated factor 4
DIXDC1 DIX domain containing 1
DMTN dematin actin binding protein
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17
DNMBP dynamin binding protein
EDIL3 EGF-like repeats and discoidin I-like domains 3
GMEB1 glucocorticoid modulatory element binding protein 1
GPALPP1 GPALPP motifs containing 1
GTPBP2 GTP binding protein 2
HAUS6 HAUS augmin-like complex, subunit 6
HCFC2 host cell factor C2
HDAC7 histone deacetylase 7
HYMAI hydatidiform mole associated and imprinted (non-protein coding)
IL7R interleukin 7 receptor
INPP1 inositol polyphosphate-1-phosphatase
INTS9 integrator complex subunit 9
KIAA0922 KIAA0922
KIF11 kinesin family member 11
LEMD3 LEM domain containing 3
LIG4 ligase IV, DNA, ATP-dependent
LOC730101 uncharacterized LOC730101
LTN1 listerin E3 ubiquitin protein ligase 1
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3
METTL4 methyltransferase like 4
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MKL2 MKL/myocardin-like 2
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit
NCS1 neuronal calcium sensor 1
NDC80 NDC80 kinetochore complex component
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NHLRC2 NHL repeat containing 2
NLK nemo-like kinase
NOC3L nucleolar complex associated 3 homolog (S. cerevisiae)
ODF2 outer dense fiber of sperm tails 2
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
OSMR oncostatin M receptor
PALMD palmdelphin
PARP16 poly (ADP-ribose) polymerase family, member 16
PCOLCE procollagen C-endopeptidase enhancer
PER3 period circadian clock 3
PLCD1 phospholipase C, delta 1
PLEKHA5 pleckstrin homology domain containing, family A member 5
PLEKHA6 pleckstrin homology domain containing, family A member 6
POLA2 polymerase (DNA directed), alpha 2, accessory subunit
PPWD1 peptidylprolyl isomerase domain and WD repeat containing 1
PRICKLE3 prickle homolog 3 (Drosophila)
R3HCC1L R3H domain and coiled-coil containing 1-like
RFWD3 ring finger and WD repeat domain 3
RGS17 regulator of G-protein signaling 17
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae)
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RPP25 ribonuclease P/MRP 25kDa subunit
SCAI suppressor of cancer cell invasion
SCHIP1 schwannomin interacting protein 1
SCYL2 SCY1-like 2 (S. cerevisiae)
SETD8 SET domain containing (lysine methyltransferase) 8
SIX1 SIX homeobox 1
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SNHG3 small nucleolar RNA host gene 3
SP140L SP140 nuclear body protein-like
SSBP3 single stranded DNA binding protein 3
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative)
TEX40 testis expressed 40
TMEM62 transmembrane protein 62
TP53BP2 tumor protein p53 binding protein 2
TRAPPC12 trafficking protein particle complex 12
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae)
TSKU tsukushi, small leucine rich proteoglycan
TTC27 tetratricopeptide repeat domain 27
TUBGCP5 tubulin, gamma complex associated protein 5
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
ZFC3H1 zinc finger, C3H1-type containing
ZFP30 ZFP30 zinc finger protein
ZNF675 zinc finger protein 675
ZW10 zw10 kinetochore protein
ZXDC ZXD family zinc finger C