thin retinal outer plexiform layer Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduced thickness of the retinal layer that is the site of synapses between the rods and cones (axons) and the horizontal and bipolar cells (dendrites) (Mammalian Phenotype Ontology, MP_0008519)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008519
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Genes

15 gene mutations causing the thin retinal outer plexiform layer phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1
ASIC3 acid sensing (proton gated) ion channel 3
ATOH7 atonal homolog 7 (Drosophila)
CABP4 calcium binding protein 4
CACNA1F calcium channel, voltage-dependent, L type, alpha 1F subunit
CACNA2D4 calcium channel, voltage-dependent, alpha 2/delta subunit 4
CRX cone-rod homeobox
ERC2 ELKS/RAB6-interacting/CAST family member 2
GJA10 gap junction protein, alpha 10, 62kDa
LARGE like-glycosyltransferase
LRP5 low density lipoprotein receptor-related protein 5
NPHP4 nephronophthisis 4
PRPH2 peripherin 2 (retinal degeneration, slow)
TRIM2 tripartite motif containing 2
UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)