thick lung-associated mesenchyme Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description increased thickness of the mesenchymal cell layer due to delay or failure of the mesenchymal compartment to thin down during the late stages of embryonic lung development (Mammalian Phenotype Ontology, MP_0011143)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0011143
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Genes

18 gene mutations causing the thick lung-associated mesenchyme phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ADAM17 ADAM metallopeptidase domain 17
BCLAF1 BCL2-associated transcription factor 1
BMPER BMP binding endothelial regulator
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1
CYLD cylindromatosis (turban tumor syndrome)
DPH1 diphthamide biosynthesis 1
FEN1 flap structure-specific endonuclease 1
FGF18 fibroblast growth factor 18
GLI2 GLI family zinc finger 2
HAT1 histone acetyltransferase 1
HOPX HOP homeobox
LAMC1 laminin, gamma 1 (formerly LAMB2)
NFIB nuclear factor I/B
PTHLH parathyroid hormone-like hormone
PTK7 protein tyrosine kinase 7 (inactive)
TGFB3 transforming growth factor, beta 3
VANGL2 VANGL planar cell polarity protein 2