thiamine-1744 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the thiamine-1744 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADD2 adducin 2 (beta)
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ANKRD40 ankyrin repeat domain 40
APP amyloid beta (A4) precursor protein
ATP5SL ATP5S-like
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRD3 bromodomain containing 3
C1QTNF3 C1q and tumor necrosis factor related protein 3
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CCDC7 coiled-coil domain containing 7
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1)
CD177 CD177 molecule
CDK6 cyclin-dependent kinase 6
CEL carboxyl ester lipase
CEP152 centrosomal protein 152kDa
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CKB creatine kinase, brain
CLDN6 claudin 6
CNTNAP1 contactin associated protein 1
COPS7B COP9 signalosome subunit 7B
COQ4 coenzyme Q4
CRAT carnitine O-acetyltransferase
DEF8 differentially expressed in FDCP 8 homolog (mouse)
DXO decapping exoribonuclease
EFR3B EFR3 homolog B (S. cerevisiae)
EHMT2 euchromatic histone-lysine N-methyltransferase 2
EIF2B4 eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa
ERCC8 excision repair cross-complementation group 8
F12 coagulation factor XII (Hageman factor)
FAM102A family with sequence similarity 102, member A
FES FES proto-oncogene, tyrosine kinase
FN1 fibronectin 1
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GLIPR1 GLI pathogenesis-related 1
GMEB1 glucocorticoid modulatory element binding protein 1
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GON4L gon-4-like (C. elegans)
GYPB glycophorin B (MNS blood group)
HDAC5 histone deacetylase 5
HIST1H4J histone cluster 1, H4j
HOXA10 homeobox A10
HRH3 histamine receptor H3
HTRA1 HtrA serine peptidase 1
IFITM1 interferon induced transmembrane protein 1
IFITM3 interferon induced transmembrane protein 3
IQSEC1 IQ motif and Sec7 domain 1
KAT8 K(lysine) acetyltransferase 8
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3
KPNB1 karyopherin (importin) beta 1
LMF2 lipase maturation factor 2
MAPKBP1 mitogen-activated protein kinase binding protein 1
MCC mutated in colorectal cancers
MPPE1 metallophosphoesterase 1
MSH3 mutS homolog 3
MST1 macrophage stimulating 1
MUC2 mucin 2, oligomeric mucus/gel-forming
MVK mevalonate kinase
MXRA8 matrix-remodelling associated 8
MYL10 myosin, light chain 10, regulatory
NCR2 natural cytotoxicity triggering receptor 2
NDRG2 NDRG family member 2
NIPAL2 NIPA-like domain containing 2
NKIRAS2 NFKB inhibitor interacting Ras-like 2
NLE1 notchless homolog 1 (Drosophila)
NPDC1 neural proliferation, differentiation and control, 1
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F
PRRC2B proline-rich coiled-coil 2B
PSG4 pregnancy specific beta-1-glycoprotein 4
RABL3 RAB, member of RAS oncogene family-like 3
RAD9A RAD9 homolog A (S. pombe)
RANBP1 RAN binding protein 1
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2
RBM47 RNA binding motif protein 47
RHBDF1 rhomboid 5 homolog 1 (Drosophila)
RORC RAR-related orphan receptor C
RPS4Y1 ribosomal protein S4, Y-linked 1
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
RTEL1 regulator of telomere elongation helicase 1
RUNDC3A RUN domain containing 3A
SCN10A sodium channel, voltage gated, type X alpha subunit
SF3A2 splicing factor 3a, subunit 2, 66kDa
SIGLEC7 sialic acid binding Ig-like lectin 7
SLC17A4 solute carrier family 17, member 4
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SMIM8 small integral membrane protein 8
SPDEF SAM pointed domain containing ETS transcription factor
SPN sialophorin
SSSCA1 Sjogren syndrome/scleroderma autoantigen 1
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TCTN1 tectonic family member 1
THEM6 thioesterase superfamily member 6
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TRPM3 transient receptor potential cation channel, subfamily M, member 3
TTC23 tetratricopeptide repeat domain 23
YIPF4 Yip1 domain family, member 4

decreased expression

Symbol Name
ABHD11 abhydrolase domain containing 11
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain
ACO1 aconitase 1, soluble
ALPK1 alpha-kinase 1
ANKRD36B ankyrin repeat domain 36B
AP1AR adaptor-related protein complex 1 associated regulatory protein
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ASB13 ankyrin repeat and SOCS box containing 13
AVEN apoptosis, caspase activation inhibitor
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BATF3 basic leucine zipper transcription factor, ATF-like 3
BCL7C B-cell CLL/lymphoma 7C
C10ORF88 chromosome 10 open reading frame 88
C11ORF68 chromosome 11 open reading frame 68
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
C21ORF59 chromosome 21 open reading frame 59
C5ORF30 chromosome 5 open reading frame 30
CD82 CD82 molecule
CDC73 cell division cycle 73
CER1 cerberus 1, DAN family BMP antagonist
CISH cytokine inducible SH2-containing protein
CLEC7A C-type lectin domain family 7, member A
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
DAP death-associated protein
DEAF1 DEAF1 transcription factor
DHX16 DEAH (Asp-Glu-Ala-His) box polypeptide 16
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DND1 DND microRNA-mediated repression inhibitor 1
DPH2 DPH2 homolog (S. cerevisiae)
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAM188A family with sequence similarity 188, member A
FGL1 fibrinogen-like 1
FZD2 frizzled class receptor 2
GIN1 gypsy retrotransposon integrase 1
GNA12 guanine nucleotide binding protein (G protein) alpha 12
GPR183 G protein-coupled receptor 183
GRM6 glutamate receptor, metabotropic 6
GSTM3 glutathione S-transferase mu 3 (brain)
HEATR3 HEAT repeat containing 3
HIRA histone cell cycle regulator
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
IFNA17 interferon, alpha 17
INPPL1 inositol polyphosphate phosphatase-like 1
KIAA0556 KIAA0556
KIF3B kinesin family member 3B
KLHL21 kelch-like family member 21
LACTB2 lactamase, beta 2
LOC390998 ribosomal protein L10 pseudogene
LOC729164 hCG1732469
MCTP1 multiple C2 domains, transmembrane 1
MGC12488
MISP mitotic spindle positioning
MNS1 meiosis-specific nuclear structural 1
MPHOSPH8 M-phase phosphoprotein 8
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NECAB3 N-terminal EF-hand calcium binding protein 3
NHEJ1 nonhomologous end-joining factor 1
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae)
NUPL1 nucleoporin like 1
PCNXL4 pecanex-like 4 (Drosophila)
PDZD8 PDZ domain containing 8
PRPF39 pre-mRNA processing factor 39
RAB8B RAB8B, member RAS oncogene family
RABGGTA Rab geranylgeranyltransferase, alpha subunit
RBM14 RNA binding motif protein 14
RHOH ras homolog family member H
RNF170 ring finger protein 170
SCYL2 SCY1-like 2 (S. cerevisiae)
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SLC31A2 solute carrier family 31 (copper transporter), member 2
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SLMO2 slowmo homolog 2 (Drosophila)
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa
SOHLH2 spermatogenesis and oogenesis specific basic helix-loop-helix 2
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma)
STAG3 stromal antigen 3
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast)
TJP2 tight junction protein 2
TMUB2 transmembrane and ubiquitin-like domain containing 2
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TRIM5 tripartite motif containing 5
TRMT12 tRNA methyltransferase 12 homolog (S. cerevisiae)
TSR2 TSR2, 20S rRNA accumulation, homolog (S. cerevisiae)
TTPAL tocopherol (alpha) transfer protein-like
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UNG uracil-DNA glycosylase
USP39 ubiquitin specific peptidase 39
WASF1 WAS protein family, member 1
XPC xeroderma pigmentosum, complementation group C
ZBTB48 zinc finger and BTB domain containing 48
ZCCHC8 zinc finger, CCHC domain containing 8
ZNF280D zinc finger protein 280D
ZNF430 zinc finger protein 430
ZNF804A zinc finger protein 804A