thiamazole-4372 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the thiamazole-4372 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACVR1B activin A receptor, type IB
ADGRB3 adhesion G protein-coupled receptor B3
AKAP1 A kinase (PRKA) anchor protein 1
AKR1C1 aldo-keto reductase family 1, member C1
ANKLE2 ankyrin repeat and LEM domain containing 2
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
APAF1 apoptotic peptidase activating factor 1
ATXN7L1 ataxin 7-like 1
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
BAX BCL2-associated X protein
BMP15 bone morphogenetic protein 15
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
BTN3A1 butyrophilin, subfamily 3, member A1
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
CCNJL cyclin J-like
CD48 CD48 molecule
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDH16 cadherin 16, KSP-cadherin
CPEB1 cytoplasmic polyadenylation element binding protein 1
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
CT62 cancer/testis antigen 62
DEFA4 defensin, alpha 4, corticostatin
DIO2 deiodinase, iodothyronine, type II
DKFZP434L187 uncharacterized LOC26082
DOCK6 dedicator of cytokinesis 6
DRD2 dopamine receptor D2
DSC3 desmocollin 3
EMID1 EMI domain containing 1
EN2 engrailed homeobox 2
EPHA5 EPH receptor A5
ERBB2 erb-b2 receptor tyrosine kinase 2
FAM171A1 family with sequence similarity 171, member A1
FASN fatty acid synthase
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FGFBP1 fibroblast growth factor binding protein 1
FMO5 flavin containing monooxygenase 5
FRAS1 Fraser extracellular matrix complex subunit 1
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GK glycerol kinase
GLIPR1 GLI pathogenesis-related 1
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GPR135 G protein-coupled receptor 135
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIF3A hypoxia inducible factor 3, alpha subunit
HOXB9 homeobox B9
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HYAL1 hyaluronoglucosaminidase 1
ICOSLG inducible T-cell co-stimulator ligand
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGFBP5 insulin-like growth factor binding protein 5
IGLJ3 immunoglobulin lambda joining 3
ITGB8 integrin, beta 8
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KRT75 keratin 75, type II
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LMO7 LIM domain 7
LOXL2 lysyl oxidase-like 2
LRRC75B leucine rich repeat containing 75B
MIER2 mesoderm induction early response 1, family member 2
MORN1 MORN repeat containing 1
MYT1 myelin transcription factor 1
NCDN neurochondrin
NKX2-8 NK2 homeobox 8
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OR2H2 olfactory receptor, family 2, subfamily H, member 2
PCDHGA3 protocadherin gamma subfamily A, 3
PCDHGA8 protocadherin gamma subfamily A, 8
PDE10A phosphodiesterase 10A
PDLIM5 PDZ and LIM domain 5
PHLDA1 pleckstrin homology-like domain, family A, member 1
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PURG purine-rich element binding protein G
RASL10A RAS-like, family 10, member A
REC8 REC8 meiotic recombination protein
RHAG Rh-associated glycoprotein
RUNDC3A RUN domain containing 3A
SAMD4A sterile alpha motif domain containing 4A
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC5A7 solute carrier family 5 (sodium/choline cotransporter), member 7
SORBS1 sorbin and SH3 domain containing 1
TCF4 transcription factor 4
TDRD12 tudor domain containing 12
TPMT thiopurine S-methyltransferase
TTC38 tetratricopeptide repeat domain 38
USP22 ubiquitin specific peptidase 22
VCAN versican
VTCN1 V-set domain containing T cell activation inhibitor 1
WSCD2 WSC domain containing 2
YOD1 YOD1 deubiquitinase
ZNF236 zinc finger protein 236
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ALPK1 alpha-kinase 1
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARMC4 armadillo repeat containing 4
ATHL1 ATH1, acid trehalase-like 1 (yeast)
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
BIRC7 baculoviral IAP repeat containing 7
C1QB complement component 1, q subcomponent, B chain
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CCDC134 coiled-coil domain containing 134
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CFHR4 complement factor H-related 4
CGA glycoprotein hormones, alpha polypeptide
CLCN6 chloride channel, voltage-sensitive 6
CNPY4 canopy FGF signaling regulator 4
CRLF1 cytokine receptor-like factor 1
CRYGC crystallin, gamma C
CXXC4 CXXC finger protein 4
DAGLA diacylglycerol lipase, alpha
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DLK2 delta-like 2 homolog (Drosophila)
DMTN dematin actin binding protein
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DPY19L1P1 DPY19L1 pseudogene 1
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
ELSPBP1 epididymal sperm binding protein 1
ERO1LB ERO1-like beta (S. cerevisiae)
FAM198B family with sequence similarity 198, member B
FAM212B family with sequence similarity 212, member B
FBXO4 F-box protein 4
GFI1 growth factor independent 1 transcription repressor
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPRC5D G protein-coupled receptor, class C, group 5, member D
HAMP hepcidin antimicrobial peptide
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4
HDAC7 histone deacetylase 7
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HIST1H2AJ histone cluster 1, H2aj
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HOXA4 homeobox A4
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
IFI27 interferon, alpha-inducible protein 27
IGSF6 immunoglobulin superfamily, member 6
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
ITM2C integral membrane protein 2C
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KCNK5 potassium channel, two pore domain subfamily K, member 5
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
KRT16 keratin 16, type I
KRT6B keratin 6B, type II
LGALS9 lectin, galactoside-binding, soluble, 9
LMTK2 lemur tyrosine kinase 2
LOC390998 ribosomal protein L10 pseudogene
LY6D lymphocyte antigen 6 complex, locus D
MCOLN3 mucolipin 3
PADI3 peptidyl arginine deiminase, type III
PARP3 poly (ADP-ribose) polymerase family, member 3
PAX9 paired box 9
PCDH17 protocadherin 17
PCDHB13 protocadherin beta 13
PDE8B phosphodiesterase 8B
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PLAC1 placenta-specific 1
POLH polymerase (DNA directed), eta
PTPRS protein tyrosine phosphatase, receptor type, S
REM1 RAS (RAD and GEM)-like GTP-binding 1
RND1 Rho family GTPase 1
RNF126P1 ring finger protein 126 pseudogene 1
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
S100A7 S100 calcium binding protein A7
SAYSD1 SAYSVFN motif domain containing 1
SELL selectin L
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1
SLPI secretory leukocyte peptidase inhibitor
STAG3 stromal antigen 3
STIM1 stromal interaction molecule 1
STON1 stonin 1
TBX19 T-box 19
TEX14 testis expressed 14
THBS3 thrombospondin 3
TLE2 transducin-like enhancer of split 2
TM4SF4 transmembrane 4 L six family member 4
TMC5 transmembrane channel-like 5
TTLL1 tubulin tyrosine ligase-like family member 1
TUBA4B tubulin, alpha 4b
VEZT vezatin, adherens junctions transmembrane protein
WFDC2 WAP four-disulfide core domain 2
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZFHX4 zinc finger homeobox 4
ZNF532 zinc finger protein 532
ZNF574 zinc finger protein 574