theobromine-3334 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

193 genes differentially expressed following the theobromine-3334 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ADRA1B adrenoceptor alpha 1B
AKT2 v-akt murine thymoma viral oncogene homolog 2
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ARPIN actin-related protein 2/3 complex inhibitor
ARR3 arrestin 3, retinal (X-arrestin)
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
BCL2L11 BCL2-like 11 (apoptosis facilitator)
C1QTNF1 C1q and tumor necrosis factor related protein 1
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CASP4 caspase 4, apoptosis-related cysteine peptidase
CD1A CD1a molecule
CD200 CD200 molecule
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3
CLSTN3 calsyntenin 3
COL1A1 collagen, type I, alpha 1
CORT cortistatin
CSF1R colony stimulating factor 1 receptor
CTIF CBP80/20-dependent translation initiation factor
DEAF1 DEAF1 transcription factor
DSC2 desmocollin 2
EGF epidermal growth factor
EGR3 early growth response 3
EHMT1 euchromatic histone-lysine N-methyltransferase 1
FABP3 fatty acid binding protein 3, muscle and heart
FAM155A family with sequence similarity 155, member A
FCMR Fc fragment of IgM receptor
FGF4 fibroblast growth factor 4
FOXG1 forkhead box G1
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GBP1 guanylate binding protein 1, interferon-inducible
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GRM1 glutamate receptor, metabotropic 1
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HBEGF heparin-binding EGF-like growth factor
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HEG1 heart development protein with EGF-like domains 1
HRASLS2 HRAS-like suppressor 2
ICA1 islet cell autoantigen 1, 69kDa
IGFBP5 insulin-like growth factor binding protein 5
IQGAP2 IQ motif containing GTPase activating protein 2
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KDM8 lysine (K)-specific demethylase 8
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KIAA0125 KIAA0125
LRP12 low density lipoprotein receptor-related protein 12
MARK2 MAP/microtubule affinity-regulating kinase 2
MCAM melanoma cell adhesion molecule
MEF2D myocyte enhancer factor 2D
MMP17 matrix metallopeptidase 17 (membrane-inserted)
MUC3B mucin 3B, cell surface associated
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NAT6 N-acetyltransferase 6 (GCN5-related)
NKX2-5 NK2 homeobox 5
NME5 NME/NM23 family member 5
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
OTOR otoraplin
PADI3 peptidyl arginine deiminase, type III
PCDH17 protocadherin 17
PCDHGA8 protocadherin gamma subfamily A, 8
PER1 period circadian clock 1
PHC3 polyhomeotic homolog 3 (Drosophila)
PLSCR4 phospholipid scramblase 4
PODNL1 podocan-like 1
PRKCI protein kinase C, iota
PSG5 pregnancy specific beta-1-glycoprotein 5
RAB40C RAB40C, member RAS oncogene family
RFPL1S RFPL1 antisense RNA 1
RGS2 regulator of G-protein signaling 2
RIMS3 regulating synaptic membrane exocytosis 3
RND1 Rho family GTPase 1
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
SAYSD1 SAYSVFN motif domain containing 1
SCARA3 scavenger receptor class A, member 3
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
SH2D3A SH2 domain containing 3A
SIPA1 signal-induced proliferation-associated 1
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SOCS7 suppressor of cytokine signaling 7
SOX3 SRY (sex determining region Y)-box 3
SPPL2B signal peptide peptidase like 2B
TAOK2 TAO kinase 2
TBC1D8 TBC1 domain family, member 8 (with GRAM domain)
TCF3 transcription factor 3
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
TGM2 transglutaminase 2
TMEM63A transmembrane protein 63A
TMPRSS3 transmembrane protease, serine 3
TRIM36 tripartite motif containing 36
TRO trophinin
UHRF1BP1L UHRF1 binding protein 1-like
USP46 ubiquitin specific peptidase 46
VIM vimentin
ZNF350 zinc finger protein 350
ZNF589 zinc finger protein 589

decreased expression

Symbol Name
ACTL8 actin-like 8
AFF4 AF4/FMR2 family, member 4
ALG12 ALG12, alpha-1,6-mannosyltransferase
ANP32A-IT1 ANP32A intronic transcript 1
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
ARMCX2 armadillo repeat containing, X-linked 2
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BAHCC1 BAH domain and coiled-coil containing 1
C7ORF43 chromosome 7 open reading frame 43
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CBX8 chromobox homolog 8
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCNO cyclin O
CD83 CD83 molecule
CDK18 cyclin-dependent kinase 18
CENPO centromere protein O
CSTA cystatin A (stefin A)
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DGKD diacylglycerol kinase, delta 130kDa
DYSF dysferlin
EFNA1 ephrin-A1
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
FGL1 fibrinogen-like 1
FILIP1L filamin A interacting protein 1-like
FKBP5 FK506 binding protein 5
FMO4 flavin containing monooxygenase 4
GAMT guanidinoacetate N-methyltransferase
GDAP1 ganglioside induced differentiation associated protein 1
GLB1L galactosidase, beta 1-like
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GNG13 guanine nucleotide binding protein (G protein), gamma 13
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GRAMD4 GRAM domain containing 4
GSTM2 glutathione S-transferase mu 2 (muscle)
H1F0 H1 histone family, member 0
HCAR3 hydroxycarboxylic acid receptor 3
HDAC7 histone deacetylase 7
HIST1H2AJ histone cluster 1, H2aj
HIST1H4F histone cluster 1, H4f
HPN hepsin
HYI hydroxypyruvate isomerase (putative)
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IL22 interleukin 22
INO80D INO80 complex subunit D
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCNK12 potassium channel, two pore domain subfamily K, member 12
KIAA0319L KIAA0319-like
LRP2 low density lipoprotein receptor-related protein 2
LY6D lymphocyte antigen 6 complex, locus D
MAGEA6 melanoma antigen family A6
MB myoglobin
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MXD3 MAX dimerization protein 3
MYO1E myosin IE
MYO1F myosin IF
MYOZ3 myozenin 3
NPM3 nucleophosmin/nucleoplasmin 3
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PCDHB8 protocadherin beta 8
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PRR14L proline rich 14-like
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B)
RETSAT retinol saturase (all-trans-retinol 13,14-reductase)
RPAIN RPA interacting protein
RPL13P5 ribosomal protein L13 pseudogene 5
RRAGB Ras-related GTP binding B
RUNDC3B RUN domain containing 3B
S100A9 S100 calcium binding protein A9
SCAI suppressor of cancer cell invasion
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SKIL SKI-like proto-oncogene
SPTBN2 spectrin, beta, non-erythrocytic 2
SREK1IP1 SREK1-interacting protein 1
STON1 stonin 1
TH tyrosine hydroxylase
THRB thyroid hormone receptor, beta
TMEM53 transmembrane protein 53
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TRAIP TRAF interacting protein
TRIM5 tripartite motif containing 5
TSGA10 testis specific, 10
UPP1 uridine phosphorylase 1
USB1 U6 snRNA biogenesis 1
USP19 ubiquitin specific peptidase 19
ZBTB44 zinc finger and BTB domain containing 44
ZBTB6 zinc finger and BTB domain containing 6
ZNF358 zinc finger protein 358
ZSCAN26 zinc finger and SCAN domain containing 26