thalidomide-7288 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the thalidomide-7288 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AADAC arylacetamide deacetylase
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABHD2 abhydrolase domain containing 2
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ANKMY1 ankyrin repeat and MYND domain containing 1
ANOS1 anosmin 1
APC adenomatous polyposis coli
APOC1 apolipoprotein C-I
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARMCX2 armadillo repeat containing, X-linked 2
ARNT aryl hydrocarbon receptor nuclear translocator
BCR breakpoint cluster region
C3 complement component 3
C7 complement component 7
CACYBP calcyclin binding protein
CD58 CD58 molecule
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CFLAR CASP8 and FADD-like apoptosis regulator
COL3A1 collagen, type III, alpha 1
CRY2 cryptochrome circadian clock 2
CTNND2 catenin (cadherin-associated protein), delta 2
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1
CYP11B1 cytochrome P450, family 11, subfamily B, polypeptide 1
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2
DCN decorin
DLK1 delta-like 1 homolog (Drosophila)
DVL3 dishevelled segment polarity protein 3
EGFR epidermal growth factor receptor
FAS Fas cell surface death receptor
FBXO46 F-box protein 46
FGL1 fibrinogen-like 1
FLT1 fms-related tyrosine kinase 1
GPR176 G protein-coupled receptor 176
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like)
GPR6 G protein-coupled receptor 6
GPR75 G protein-coupled receptor 75
GSTA1 glutathione S-transferase alpha 1
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HOXA4 homeobox A4
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
IL33 interleukin 33
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KCTD13 potassium channel tetramerization domain containing 13
KIF5C kinesin family member 5C
KRT6B keratin 6B, type II
LRP3 low density lipoprotein receptor-related protein 3
MAP7 microtubule-associated protein 7
METTL7A methyltransferase like 7A
MGP matrix Gla protein
MMP3 matrix metallopeptidase 3
NINJ1 ninjurin 1
PGLYRP4 peptidoglycan recognition protein 4
PITX1 paired-like homeodomain 1
PKP3 plakophilin 3
PMCH pro-melanin-concentrating hormone
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
RIF1 replication timing regulatory factor 1
RIN3 Ras and Rab interactor 3
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RRAGB Ras-related GTP binding B
SEPP1 selenoprotein P, plasma, 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SFRP1 secreted frizzled-related protein 1
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
STAC SH3 and cysteine rich domain
STAR steroidogenic acute regulatory protein
STMN4 stathmin-like 4
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
TBC1D2B TBC1 domain family, member 2B
TELO2 telomere maintenance 2
TMEM53 transmembrane protein 53
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNK1 tyrosine kinase, non-receptor, 1
TPM2 tropomyosin 2 (beta)
TRAK1 trafficking protein, kinesin binding 1
TRIM25 tripartite motif containing 25
TRIM66 tripartite motif containing 66
TTC30A tetratricopeptide repeat domain 30A
TUSC3 tumor suppressor candidate 3
TYMS thymidylate synthetase
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
URI1 URI1, prefoldin-like chaperone
WDR62 WD repeat domain 62
WIPI2 WD repeat domain, phosphoinositide interacting 2
WNK1 WNK lysine deficient protein kinase 1
ZKSCAN1 zinc finger with KRAB and SCAN domains 1
ZNF253 zinc finger protein 253
ZNF428 zinc finger protein 428
ZNF692 zinc finger protein 692

decreased expression

Symbol Name
ACOT8 acyl-CoA thioesterase 8
ACSL4 acyl-CoA synthetase long-chain family member 4
AEN apoptosis enhancing nuclease
AKTIP AKT interacting protein
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide
C19ORF40 chromosome 19 open reading frame 40
CALCOCO1 calcium binding and coiled-coil domain 1
CAPN15 calpain 15
CCDC47 coiled-coil domain containing 47
CCDC6 coiled-coil domain containing 6
CCNJL cyclin J-like
CCP110 centriolar coiled coil protein 110kDa
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CENPT centromere protein T
CEP72 centrosomal protein 72kDa
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHMP6 charged multivesicular body protein 6
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CINP cyclin-dependent kinase 2 interacting protein
CLSPN claspin
CNKSR1 connector enhancer of kinase suppressor of Ras 1
COG4 component of oligomeric golgi complex 4
CTNNBL1 catenin, beta like 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DHRS3 dehydrogenase/reductase (SDR family) member 3
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8
DOCK1 dedicator of cytokinesis 1
EDC4 enhancer of mRNA decapping 4
EIF5A2 eukaryotic translation initiation factor 5A2
F8 coagulation factor VIII, procoagulant component
FAM102A family with sequence similarity 102, member A
FAM131A family with sequence similarity 131, member A
FAM50B family with sequence similarity 50, member B
FANCF Fanconi anemia, complementation group F
FBP1 fructose-1,6-bisphosphatase 1
FBXL2 F-box and leucine-rich repeat protein 2
GPATCH2L G patch domain containing 2-like
HDAC5 histone deacetylase 5
HIRA histone cell cycle regulator
HIST1H2AM histone cluster 1, H2am
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KIAA1462 KIAA1462
KRT4 keratin 4, type II
LMF1 lipase maturation factor 1
LMNB1 lamin B1
MANBA mannosidase, beta A, lysosomal
MAST3 microtubule associated serine/threonine kinase 3
MB myoglobin
MCMBP minichromosome maintenance complex binding protein
MED15 mediator complex subunit 15
METTL1 methyltransferase like 1
MRPL44 mitochondrial ribosomal protein L44
MUC3B mucin 3B, cell surface associated
MXRA8 matrix-remodelling associated 8
NARFL nuclear prelamin A recognition factor-like
NFIX nuclear factor I/X (CCAAT-binding transcription factor)
NME5 NME/NM23 family member 5
OPLAH 5-oxoprolinase (ATP-hydrolysing)
ORAI3 ORAI calcium release-activated calcium modulator 3
PCSK7 proprotein convertase subtilisin/kexin type 7
PDIA3 protein disulfide isomerase family A, member 3
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PHKG2 phosphorylase kinase, gamma 2 (testis)
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
POLH polymerase (DNA directed), eta
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RCAN3 RCAN family member 3
REEP4 receptor accessory protein 4
RIN1 Ras and Rab interactor 1
RNF126P1 ring finger protein 126 pseudogene 1
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
RPAP1 RNA polymerase II associated protein 1
RPL23AP32 ribosomal protein L23a pseudogene 32
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
S100A3 S100 calcium binding protein A3
SCARA3 scavenger receptor class A, member 3
SFT2D2 SFT2 domain containing 2
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
SUN2 Sad1 and UNC84 domain containing 2
TEP1 telomerase-associated protein 1
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TMEM132A transmembrane protein 132A
TNRC6B trinucleotide repeat containing 6B
TUBA3C tubulin, alpha 3c
USP27X ubiquitin specific peptidase 27, X-linked
WDR91 WD repeat domain 91
ZNF358 zinc finger protein 358
ZNF787 zinc finger protein 787