Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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197 genes differentially expressed following the thalidomide-606 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ADAMTS2 | ADAM metallopeptidase with thrombospondin type 1 motif, 2 |
ADORA3 | adenosine A3 receptor |
AGXT | alanine-glyoxylate aminotransferase |
AP3B1 | adaptor-related protein complex 3, beta 1 subunit |
APBB1 | amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) |
APOBEC3C | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C |
APOM | apolipoprotein M |
ARHGAP33 | Rho GTPase activating protein 33 |
ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 |
ARRB2 | arrestin, beta 2 |
AXIN1 | axin 1 |
BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
CCDC40 | coiled-coil domain containing 40 |
CCDC71 | coiled-coil domain containing 71 |
CCDC87 | coiled-coil domain containing 87 |
CCR5 | chemokine (C-C motif) receptor 5 (gene/pseudogene) |
CD6 | CD6 molecule |
CDH22 | cadherin 22, type 2 |
CIITA | class II, major histocompatibility complex, transactivator |
COL3A1 | collagen, type III, alpha 1 |
CRYAB | crystallin, alpha B |
CTAGE9 | CTAGE family, member 9 |
CYP2B6 | cytochrome P450, family 2, subfamily B, polypeptide 6 |
CYSLTR2 | cysteinyl leukotriene receptor 2 |
DEF6 | differentially expressed in FDCP 6 homolog (mouse) |
DENND3 | DENN/MADD domain containing 3 |
DNAJC16 | DnaJ (Hsp40) homolog, subfamily C, member 16 |
DOK5 | docking protein 5 |
DYSF | dysferlin |
E2F1 | E2F transcription factor 1 |
EHMT2 | euchromatic histone-lysine N-methyltransferase 2 |
F11 | coagulation factor XI |
FBXO42 | F-box protein 42 |
FCN3 | ficolin (collagen/fibrinogen domain containing) 3 |
FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
GAB1 | GRB2-associated binding protein 1 |
GPR3 | G protein-coupled receptor 3 |
GPSM3 | G-protein signaling modulator 3 |
GRM1 | glutamate receptor, metabotropic 1 |
HGF | hepatocyte growth factor (hepapoietin A; scatter factor) |
HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
IL15RA | interleukin 15 receptor, alpha |
KCNQ4 | potassium channel, voltage gated KQT-like subfamily Q, member 4 |
KIR2DL3 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 |
KIR2DL5A | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A |
KLF6 | Kruppel-like factor 6 |
LENEP | lens epithelial protein |
LOC100127972 | uncharacterized LOC100127972 |
LPAR1 | lysophosphatidic acid receptor 1 |
LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
MAU2 | MAU2 sister chromatid cohesion factor |
METAP2 | methionyl aminopeptidase 2 |
MIER2 | mesoderm induction early response 1, family member 2 |
MRPL41 | mitochondrial ribosomal protein L41 |
MTF2 | metal response element binding transcription factor 2 |
NAP1L2 | nucleosome assembly protein 1-like 2 |
OR10H3 | olfactory receptor, family 10, subfamily H, member 3 |
OR2H1 | olfactory receptor, family 2, subfamily H, member 1 |
OR2H2 | olfactory receptor, family 2, subfamily H, member 2 |
OR52A1 | olfactory receptor, family 52, subfamily A, member 1 |
OSBPL7 | oxysterol binding protein-like 7 |
PCYT1B | phosphate cytidylyltransferase 1, choline, beta |
PECAM1 | platelet/endothelial cell adhesion molecule 1 |
PPEF1 | protein phosphatase, EF-hand calcium binding domain 1 |
PRELP | proline/arginine-rich end leucine-rich repeat protein |
PRPF18 | pre-mRNA processing factor 18 |
RDH5 | retinol dehydrogenase 5 (11-cis/9-cis) |
RPS11 | ribosomal protein S11 |
RUNX2 | runt-related transcription factor 2 |
SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A |
SHMT1 | serine hydroxymethyltransferase 1 (soluble) |
SLC39A2 | solute carrier family 39 (zinc transporter), member 2 |
SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
SLC6A5 | solute carrier family 6 (neurotransmitter transporter), member 5 |
SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
SLC7A9 | solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 |
SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 |
SMYD5 | SMYD family member 5 |
SNTG1 | syntrophin, gamma 1 |
SPN | sialophorin |
TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 |
TAOK2 | TAO kinase 2 |
TGM5 | transglutaminase 5 |
TLN2 | talin 2 |
TLR5 | toll-like receptor 5 |
TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
TSKS | testis-specific serine kinase substrate |
TTC9 | tetratricopeptide repeat domain 9 |
TTR | transthyretin |
UBE4B | ubiquitination factor E4B |
UBQLN4 | ubiquilin 4 |
USP2 | ubiquitin specific peptidase 2 |
WDR48 | WD repeat domain 48 |
WIPF1 | WAS/WASL interacting protein family, member 1 |
ZC3H3 | zinc finger CCCH-type containing 3 |
ZNF609 | zinc finger protein 609 |
Symbol | Name |
---|---|
ABCG4 | ATP-binding cassette, sub-family G (WHITE), member 4 |
ACSF2 | acyl-CoA synthetase family member 2 |
ADGRB1 | adhesion G protein-coupled receptor B1 |
ADIRF | adipogenesis regulatory factor |
ALX3 | ALX homeobox 3 |
AMT | aminomethyltransferase |
AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
ARR3 | arrestin 3, retinal (X-arrestin) |
BAGE | B melanoma antigen |
C16ORF59 | chromosome 16 open reading frame 59 |
C4BPA | complement component 4 binding protein, alpha |
C4ORF29 | chromosome 4 open reading frame 29 |
CA5BP1 | carbonic anhydrase VB pseudogene 1 |
CARS2 | cysteinyl-tRNA synthetase 2, mitochondrial (putative) |
CAV3 | caveolin 3 |
CBX8 | chromobox homolog 8 |
CCK | cholecystokinin |
CCL25 | chemokine (C-C motif) ligand 25 |
CCNL2 | cyclin L2 |
CEP41 | centrosomal protein 41kDa |
CFAP70 | cilia and flagella associated protein 70 |
CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
CHST12 | carbohydrate (chondroitin 4) sulfotransferase 12 |
CKMT2 | creatine kinase, mitochondrial 2 (sarcomeric) |
COBL | cordon-bleu WH2 repeat protein |
CPOX | coproporphyrinogen oxidase |
CYP20A1 | cytochrome P450, family 20, subfamily A, polypeptide 1 |
DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal |
DEPDC5 | DEP domain containing 5 |
DHTKD1 | dehydrogenase E1 and transketolase domain containing 1 |
DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
DNMT3B | DNA (cytosine-5-)-methyltransferase 3 beta |
DTWD1 | DTW domain containing 1 |
EFHC1 | EF-hand domain (C-terminal) containing 1 |
EPHA4 | EPH receptor A4 |
FCHO1 | FCH domain only 1 |
FOLR2 | folate receptor 2 (fetal) |
GAPDHS | glyceraldehyde-3-phosphate dehydrogenase, spermatogenic |
GDF2 | growth differentiation factor 2 |
GLMN | glomulin, FKBP associated protein |
GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 |
GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
GPR15 | G protein-coupled receptor 15 |
GPRC5D | G protein-coupled receptor, class C, group 5, member D |
GTF2H4 | general transcription factor IIH, polypeptide 4, 52kDa |
HIST1H1B | histone cluster 1, H1b |
HIST1H2AM | histone cluster 1, H2am |
HPX | hemopexin |
IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
IL19 | interleukin 19 |
JMJD4 | jumonji domain containing 4 |
KLHL25 | kelch-like family member 25 |
KLHL36 | kelch-like family member 36 |
KRI1 | KRI1 homolog (S. cerevisiae) |
KRT75 | keratin 75, type II |
LOC100272216 | uncharacterized LOC100272216 |
MAP3K14 | mitogen-activated protein kinase kinase kinase 14 |
MCOLN3 | mucolipin 3 |
MGA | MGA, MAX dimerization protein |
MMP3 | matrix metallopeptidase 3 |
MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A |
NAT9 | N-acetyltransferase 9 (GCN5-related, putative) |
NFIC | nuclear factor I/C (CCAAT-binding transcription factor) |
NOX5 | NADPH oxidase, EF-hand calcium binding domain 5 |
OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
PCDHB6 | protocadherin beta 6 |
PCP4 | Purkinje cell protein 4 |
PDK2 | pyruvate dehydrogenase kinase, isozyme 2 |
PLCD1 | phospholipase C, delta 1 |
PLEK2 | pleckstrin 2 |
PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
POGLUT1 | protein O-glucosyltransferase 1 |
POLD4 | polymerase (DNA-directed), delta 4, accessory subunit |
PPIP5K1 | diphosphoinositol pentakisphosphate kinase 1 |
PQLC2 | PQ loop repeat containing 2 |
RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 |
RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
RECQL4 | RecQ protein-like 4 |
RGL1 | ral guanine nucleotide dissociation stimulator-like 1 |
RRAS | related RAS viral (r-ras) oncogene homolog |
RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
SOAT1 | sterol O-acyltransferase 1 |
STARD5 | StAR-related lipid transfer (START) domain containing 5 |
STX1A | syntaxin 1A (brain) |
SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
SYT17 | synaptotagmin XVII |
TARBP1 | TAR (HIV-1) RNA binding protein 1 |
TCEA2 | transcription elongation factor A (SII), 2 |
TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) |
TMEM127 | transmembrane protein 127 |
TMEM187 | transmembrane protein 187 |
TMEM51 | transmembrane protein 51 |
TREM2 | triggering receptor expressed on myeloid cells 2 |
TTC13 | tetratricopeptide repeat domain 13 |
VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
WNT7A | wingless-type MMTV integration site family, member 7A |
ZNF358 | zinc finger protein 358 |
ZNF652 | zinc finger protein 652 |
ZNF83 | zinc finger protein 83 |