thalidomide-606 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools


197 genes differentially expressed following the thalidomide-606 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2
ADORA3 adenosine A3 receptor
AGXT alanine-glyoxylate aminotransferase
AP3B1 adaptor-related protein complex 3, beta 1 subunit
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
APOM apolipoprotein M
ARHGAP33 Rho GTPase activating protein 33
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ARRB2 arrestin, beta 2
AXIN1 axin 1
BAZ2A bromodomain adjacent to zinc finger domain, 2A
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CCDC40 coiled-coil domain containing 40
CCDC71 coiled-coil domain containing 71
CCDC87 coiled-coil domain containing 87
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD6 CD6 molecule
CDH22 cadherin 22, type 2
CIITA class II, major histocompatibility complex, transactivator
COL3A1 collagen, type III, alpha 1
CRYAB crystallin, alpha B
CTAGE9 CTAGE family, member 9
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
CYSLTR2 cysteinyl leukotriene receptor 2
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DENND3 DENN/MADD domain containing 3
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16
DOK5 docking protein 5
DYSF dysferlin
E2F1 E2F transcription factor 1
EHMT2 euchromatic histone-lysine N-methyltransferase 2
F11 coagulation factor XI
FBXO42 F-box protein 42
FCN3 ficolin (collagen/fibrinogen domain containing) 3
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GAB1 GRB2-associated binding protein 1
GPR3 G protein-coupled receptor 3
GPSM3 G-protein signaling modulator 3
GRM1 glutamate receptor, metabotropic 1
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IL15RA interleukin 15 receptor, alpha
KCNQ4 potassium channel, voltage gated KQT-like subfamily Q, member 4
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
KLF6 Kruppel-like factor 6
LENEP lens epithelial protein
LOC100127972 uncharacterized LOC100127972
LPAR1 lysophosphatidic acid receptor 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAU2 MAU2 sister chromatid cohesion factor
METAP2 methionyl aminopeptidase 2
MIER2 mesoderm induction early response 1, family member 2
MRPL41 mitochondrial ribosomal protein L41
MTF2 metal response element binding transcription factor 2
NAP1L2 nucleosome assembly protein 1-like 2
OR10H3 olfactory receptor, family 10, subfamily H, member 3
OR2H1 olfactory receptor, family 2, subfamily H, member 1
OR2H2 olfactory receptor, family 2, subfamily H, member 2
OR52A1 olfactory receptor, family 52, subfamily A, member 1
OSBPL7 oxysterol binding protein-like 7
PCYT1B phosphate cytidylyltransferase 1, choline, beta
PECAM1 platelet/endothelial cell adhesion molecule 1
PPEF1 protein phosphatase, EF-hand calcium binding domain 1
PRELP proline/arginine-rich end leucine-rich repeat protein
PRPF18 pre-mRNA processing factor 18
RDH5 retinol dehydrogenase 5 (11-cis/9-cis)
RPS11 ribosomal protein S11
RUNX2 runt-related transcription factor 2
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SLC39A2 solute carrier family 39 (zinc transporter), member 2
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC6A5 solute carrier family 6 (neurotransmitter transporter), member 5
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SMYD5 SMYD family member 5
SNTG1 syntrophin, gamma 1
SPN sialophorin
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TAOK2 TAO kinase 2
TGM5 transglutaminase 5
TLN2 talin 2
TLR5 toll-like receptor 5
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TSKS testis-specific serine kinase substrate
TTC9 tetratricopeptide repeat domain 9
TTR transthyretin
UBE4B ubiquitination factor E4B
UBQLN4 ubiquilin 4
USP2 ubiquitin specific peptidase 2
WDR48 WD repeat domain 48
WIPF1 WAS/WASL interacting protein family, member 1
ZC3H3 zinc finger CCCH-type containing 3
ZNF609 zinc finger protein 609

decreased expression

Symbol Name
ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4
ACSF2 acyl-CoA synthetase family member 2
ADGRB1 adhesion G protein-coupled receptor B1
ADIRF adipogenesis regulatory factor
ALX3 ALX homeobox 3
AMT aminomethyltransferase
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
ARR3 arrestin 3, retinal (X-arrestin)
BAGE B melanoma antigen
C16ORF59 chromosome 16 open reading frame 59
C4BPA complement component 4 binding protein, alpha
C4ORF29 chromosome 4 open reading frame 29
CA5BP1 carbonic anhydrase VB pseudogene 1
CARS2 cysteinyl-tRNA synthetase 2, mitochondrial (putative)
CAV3 caveolin 3
CBX8 chromobox homolog 8
CCK cholecystokinin
CCL25 chemokine (C-C motif) ligand 25
CCNL2 cyclin L2
CEP41 centrosomal protein 41kDa
CFAP70 cilia and flagella associated protein 70
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric)
COBL cordon-bleu WH2 repeat protein
CPOX coproporphyrinogen oxidase
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DEPDC5 DEP domain containing 5
DHTKD1 dehydrogenase E1 and transketolase domain containing 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DTWD1 DTW domain containing 1
EFHC1 EF-hand domain (C-terminal) containing 1
EPHA4 EPH receptor A4
FCHO1 FCH domain only 1
FOLR2 folate receptor 2 (fetal)
GAPDHS glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
GDF2 growth differentiation factor 2
GLMN glomulin, FKBP associated protein
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GPR15 G protein-coupled receptor 15
GPRC5D G protein-coupled receptor, class C, group 5, member D
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa
HIST1H1B histone cluster 1, H1b
HIST1H2AM histone cluster 1, H2am
HPX hemopexin
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IL19 interleukin 19
JMJD4 jumonji domain containing 4
KLHL25 kelch-like family member 25
KLHL36 kelch-like family member 36
KRI1 KRI1 homolog (S. cerevisiae)
KRT75 keratin 75, type II
LOC100272216 uncharacterized LOC100272216
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MCOLN3 mucolipin 3
MGA MGA, MAX dimerization protein
MMP3 matrix metallopeptidase 3
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
NAT9 N-acetyltransferase 9 (GCN5-related, putative)
NFIC nuclear factor I/C (CCAAT-binding transcription factor)
NOX5 NADPH oxidase, EF-hand calcium binding domain 5
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PCDHB6 protocadherin beta 6
PCP4 Purkinje cell protein 4
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PLCD1 phospholipase C, delta 1
PLEK2 pleckstrin 2
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
POGLUT1 protein O-glucosyltransferase 1
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PQLC2 PQ loop repeat containing 2
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RECQL4 RecQ protein-like 4
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RRAS related RAS viral (r-ras) oncogene homolog
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SOAT1 sterol O-acyltransferase 1
STARD5 StAR-related lipid transfer (START) domain containing 5
STX1A syntaxin 1A (brain)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
SYT17 synaptotagmin XVII
TARBP1 TAR (HIV-1) RNA binding protein 1
TCEA2 transcription elongation factor A (SII), 2
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast)
TMEM127 transmembrane protein 127
TMEM187 transmembrane protein 187
TMEM51 transmembrane protein 51
TREM2 triggering receptor expressed on myeloid cells 2
TTC13 tetratricopeptide repeat domain 13
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WNT7A wingless-type MMTV integration site family, member 7A
ZNF358 zinc finger protein 358
ZNF652 zinc finger protein 652
ZNF83 zinc finger protein 83