thalidomide-266 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the thalidomide-266 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABLIM3 actin binding LIM protein family, member 3
ADAP1 ArfGAP with dual PH domains 1
ARHGAP19 Rho GTPase activating protein 19
BAIAP3 BAI1-associated protein 3
BIK BCL2-interacting killer (apoptosis-inducing)
BTD biotinidase
C10ORF76 chromosome 10 open reading frame 76
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CBX2 chromobox homolog 2
CCHCR1 coiled-coil alpha-helical rod protein 1
CDK10 cyclin-dependent kinase 10
CDK9 cyclin-dependent kinase 9
CDYL chromodomain protein, Y-like
CHPF2 chondroitin polymerizing factor 2
CHRM4 cholinergic receptor, muscarinic 4
CLASP2 cytoplasmic linker associated protein 2
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa
CTNND2 catenin (cadherin-associated protein), delta 2
DGCR2 DiGeorge syndrome critical region gene 2
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8
DLEC1 deleted in lung and esophageal cancer 1
DUS2 dihydrouridine synthase 2
E2F1 E2F transcription factor 1
ERCC1 excision repair cross-complementation group 1
FAR2 fatty acyl CoA reductase 2
FGFR2 fibroblast growth factor receptor 2
FKBP8 FK506 binding protein 8, 38kDa
FNDC3A fibronectin type III domain containing 3A
FRS2 fibroblast growth factor receptor substrate 2
FSD1 fibronectin type III and SPRY domain containing 1
GM2A GM2 ganglioside activator
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HCG9 HLA complex group 9 (non-protein coding)
HIST1H2BD histone cluster 1, H2bd
HSPA4 heat shock 70kDa protein 4
IFT122 intraflagellar transport 122
LAMA3 laminin, alpha 3
LIAS lipoic acid synthetase
LMF1 lipase maturation factor 1
LRRC23 leucine rich repeat containing 23
MBD1 methyl-CpG binding domain protein 1
MBNL2 muscleblind-like splicing regulator 2
MON1B MON1 secretory trafficking family member B
MPPE1 metallophosphoesterase 1
MVK mevalonate kinase
MZF1 myeloid zinc finger 1
NOP16 NOP16 nucleolar protein
NRGN neurogranin (protein kinase C substrate, RC3)
NUP93 nucleoporin 93kDa
OAZ3 ornithine decarboxylase antizyme 3
ORAI2 ORAI calcium release-activated calcium modulator 2
PCDHB3 protocadherin beta 3
PGBD5 piggyBac transposable element derived 5
PITPNA phosphatidylinositol transfer protein, alpha
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein
POGLUT1 protein O-glucosyltransferase 1
PPARD peroxisome proliferator-activated receptor delta
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
PRKD3 protein kinase D3
PRMT7 protein arginine methyltransferase 7
PYCRL pyrroline-5-carboxylate reductase-like
RASSF7 Ras association (RalGDS/AF-6) domain family (N-terminal) member 7
RBM10 RNA binding motif protein 10
RECQL5 RecQ protein-like 5
RNF24 ring finger protein 24
RRBP1 ribosome binding protein 1
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
RSPH6A radial spoke head 6 homolog A (Chlamydomonas)
RUNX1 runt-related transcription factor 1
SAFB scaffold attachment factor B
SAMHD1 SAM domain and HD domain 1
SBNO2 strawberry notch homolog 2 (Drosophila)
SH3BP2 SH3-domain binding protein 2
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLC4A2 solute carrier family 4 (anion exchanger), member 2
STK11 serine/threonine kinase 11
SURF2 surfeit 2
TBL1X transducin (beta)-like 1X-linked
TFE3 transcription factor binding to IGHM enhancer 3
TJP3 tight junction protein 3
TMPRSS2 transmembrane protease, serine 2
TNK1 tyrosine kinase, non-receptor, 1
TOB2 transducer of ERBB2, 2
TPP1 tripeptidyl peptidase I
TRAFD1 TRAF-type zinc finger domain containing 1
TTLL4 tubulin tyrosine ligase-like family member 4
UBE2O ubiquitin-conjugating enzyme E2O
UBE4B ubiquitination factor E4B
VAC14 Vac14 homolog (S. cerevisiae)
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
VRK3 vaccinia related kinase 3
WDR13 WD repeat domain 13
WDR48 WD repeat domain 48
YIPF6 Yip1 domain family, member 6
ZGPAT zinc finger, CCCH-type with G patch domain
ZNF668 zinc finger protein 668

decreased expression

Symbol Name
ADAM30 ADAM metallopeptidase domain 30
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6
AHR aryl hydrocarbon receptor
APCS amyloid P component, serum
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
ARMC4 armadillo repeat containing 4
ARSF arylsulfatase F
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATXN3L ataxin 3-like
BHMT betaine--homocysteine S-methyltransferase
C3AR1 complement component 3a receptor 1
CACNG2 calcium channel, voltage-dependent, gamma subunit 2
CD300C CD300c molecule
CD79A CD79a molecule, immunoglobulin-associated alpha
CDKL3 cyclin-dependent kinase-like 3
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon
CIDEA cell death-inducing DFFA-like effector a
CLCA1 chloride channel accessory 1
CLDN7 claudin 7
COPZ2 coatomer protein complex, subunit zeta 2
CORT cortistatin
DIO3 deiodinase, iodothyronine, type III
DSE dermatan sulfate epimerase
DUSP13 dual specificity phosphatase 13
DUSP2 dual specificity phosphatase 2
EFCAB1 EF-hand calcium binding domain 1
ELAVL4 ELAV like neuron-specific RNA binding protein 4
ENOX1 ecto-NOX disulfide-thiol exchanger 1
EYA1 EYA transcriptional coactivator and phosphatase 1
FGFBP1 fibroblast growth factor binding protein 1
FHL3 four and a half LIM domains 3
FOLR2 folate receptor 2 (fetal)
GAL3ST4 galactose-3-O-sulfotransferase 4
GAPDHS glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
GATA1 GATA binding protein 1 (globin transcription factor 1)
GJC1 gap junction protein, gamma 1, 45kDa
GLDC glycine dehydrogenase (decarboxylating)
GPR15 G protein-coupled receptor 15
GRM2 glutamate receptor, metabotropic 2
HOPX HOP homeobox
HOXA6 homeobox A6
HOXB1 homeobox B1
HSPB3 heat shock 27kDa protein 3
IGFALS insulin-like growth factor binding protein, acid labile subunit
IL12RB1 interleukin 12 receptor, beta 1
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
KLHL3 kelch-like family member 3
KLRK1 killer cell lectin-like receptor subfamily K, member 1
KRT37 keratin 37, type I
KRT75 keratin 75, type II
KRT85 keratin 85, type II
LINC00339 long intergenic non-protein coding RNA 339
LINC00474 long intergenic non-protein coding RNA 474
LINC01558 long intergenic non-protein coding RNA 1558
LOC145678 uncharacterized LOC145678
MAGEB2 melanoma antigen family B2
MAGEC1 melanoma antigen family C1
MT4 metallothionein 4
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
NMNAT2 nicotinamide nucleotide adenylyltransferase 2
NOTCH4 notch 4
NPY4R neuropeptide Y receptor Y4
OR2C1 olfactory receptor, family 2, subfamily C, member 1
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PACS1 phosphofurin acidic cluster sorting protein 1
PALM paralemmin
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PNOC prepronociceptin
PPP1R17 protein phosphatase 1, regulatory subunit 17
PRDM14 PR domain containing 14
RASIP1 Ras interacting protein 1
RHOF ras homolog family member F (in filopodia)
RNF185 ring finger protein 185
RPS2P45 ribosomal protein S2 pseudogene 45
RPS4Y1 ribosomal protein S4, Y-linked 1
SAG S-antigen; retina and pineal gland (arrestin)
SCNN1G sodium channel, non voltage gated 1 gamma subunit
SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
SH3BP1 SH3-domain binding protein 1
SMO smoothened, frizzled class receptor
STAB2 stabilin 2
STARD8 StAR-related lipid transfer (START) domain containing 8
SULT4A1 sulfotransferase family 4A, member 1
TIMM10 translocase of inner mitochondrial membrane 10 homolog (yeast)
TMEM176A transmembrane protein 176A
USP20 ubiquitin specific peptidase 20
USP29 ubiquitin specific peptidase 29
UTP11L UTP11-like, U3 small nucleolar ribonucleoprotein (yeast)
VENTX VENT homeobox
VSIG4 V-set and immunoglobulin domain containing 4
ZFR2 zinc finger RNA binding protein 2
ZNF280A zinc finger protein 280A
ZNF286A zinc finger protein 286A
ZNF573 zinc finger protein 573