tetraspanin-enriched microdomain Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A pre-organized unit composed either of adhesion molecules (mainly integrins and members of the Ig superfamily), signaling receptors and/or enzyme-enriched plasma membrane domains that compartmentalizes cellular processes. Tetraspanin-enriched microdomains might be specially suited for the regulation of avidity of adhesion receptors and the compartmentalization of enzymatic activities. (Gene Ontology, GO_0097197)
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Genes

72 proteins co-occuring with the tetraspanin-enriched microdomain cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
TNMD tenomodulin 1.85731
LECT1 leukocyte cell derived chemotaxin 1 1.85731
CD151 CD151 molecule (Raph blood group) 1.69216
CD82 CD82 molecule 1.42655
CD81 CD81 molecule 1.40522
CD63 CD63 molecule 1.1726
CD9 CD9 molecule 1.16542
TSPAN9 tetraspanin 9 1.03328
PTTG1IP pituitary tumor-transforming 1 interacting protein 0.986342
CD4 CD4 molecule 0.959748
CCR7 chemokine (C-C motif) receptor 7 0.941162
GAPT GRB2-binding adaptor protein, transmembrane 0.941162
IGSF8 immunoglobulin superfamily, member 8 0.936432
PRR7 proline rich 7 (synaptic) 0.891631
CELA3B chymotrypsin-like elastase family, member 3B 0.889321
CDCP1 CUB domain containing protein 1 0.876409
SHPK sedoheptulokinase 0.848828
TSPAN12 tetraspanin 12 0.815781
SERINC5 serine incorporator 5 0.773645
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit 0.75317
TSPAN1 tetraspanin 1 0.726599
SDCBP syndecan binding protein (syntenin) 0.701744
EPT1 ethanolaminephosphotransferase 1 0.696905
NPDC1 neural proliferation, differentiation and control, 1 0.680719
ZDHHC8 zinc finger, DHHC-type containing 8 0.668559
TM4SF1 transmembrane 4 L six family member 1 0.622229
FAM155B family with sequence similarity 155, member B 0.606128
TM4SF5 transmembrane 4 L six family member 5 0.571329
CEPT1 choline/ethanolamine phosphotransferase 1 0.475223
F3 coagulation factor III (thromboplastin, tissue factor) 0.474018
NDP Norrie disease (pseudoglioma) 0.470807
LYPLA1 lysophospholipase I 0.466799
IDO1 indoleamine 2,3-dioxygenase 1 0.450836
BST2 bone marrow stromal cell antigen 2 0.414555
DEDD death effector domain containing 0.397035
VKORC1 vitamin K epoxide reductase complex, subunit 1 0.385822
CLDN1 claudin 1 0.382354
FBL fibrillarin 0.378891
CLDN7 claudin 7 0.377738
FOXP3 forkhead box P3 0.374666
FZD4 frizzled class receptor 4 0.374666
ETV6 ets variant 6 0.337373
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) 0.3227
SCX scleraxis basic helix-loop-helix transcription factor 0.308867
ALDOC aldolase C, fructose-bisphosphate 0.308867
LIM2 lens intrinsic membrane protein 2, 19kDa 0.307377
ICAM1 intercellular adhesion molecule 1 0.305888
ALDOB aldolase B, fructose-bisphosphate 0.297342
GLRX glutaredoxin (thioltransferase) 0.287352
OSTC oligosaccharyltransferase complex subunit (non-catalytic) 0.282558
LAX1 lymphocyte transmembrane adaptor 1 0.2719
SELL selectin L 0.271167
NEU3 sialidase 3 (membrane sialidase) 0.262755
ALDOA aldolase A, fructose-bisphosphate 0.255107
SERPINA2 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 2 (gene/pseudogene) 0.252564
CD69 CD69 molecule 0.250389
EPCAM epithelial cell adhesion molecule 0.242437
ROM1 retinal outer segment membrane protein 1 0.230245
GLP1R glucagon-like peptide 1 receptor 0.225976
FLOT2 flotillin 2 0.220673
VCAM1 vascular cell adhesion molecule 1 0.219617
CCL21 chemokine (C-C motif) ligand 21 0.219265
FBXL20 F-box and leucine-rich repeat protein 20 0.211587
CAPNS1 calpain, small subunit 1 0.19733
PRRC2A proline-rich coiled-coil 2A 0.192423
PTN pleiotrophin 0.190495
FGD1 FYVE, RhoGEF and PH domain containing 1 0.178588
ACE angiotensin I converting enzyme 0.175745
FBLL1 fibrillarin-like 1 0.171937
UGCG UDP-glucose ceramide glucosyltransferase 0.170629
APH1A APH1A gamma secretase subunit 0.164542
KMT2A lysine (K)-specific methyltransferase 2A 0.16298