testosterone-4676 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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195 genes differentially expressed following the testosterone-4676 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
ADRBK1 adrenergic, beta, receptor kinase 1
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
APC2 adenomatosis polyposis coli 2
ASB1 ankyrin repeat and SOCS box containing 1
ATF3 activating transcription factor 3
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
AURKC aurora kinase C
BMP5 bone morphogenetic protein 5
C22ORF24 chromosome 22 open reading frame 24
CA5B carbonic anhydrase VB, mitochondrial
CD58 CD58 molecule
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CLCN7 chloride channel, voltage-sensitive 7
COL4A6 collagen, type IV, alpha 6
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding)
DMBT1 deleted in malignant brain tumors 1
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DUSP1 dual specificity phosphatase 1
EDA ectodysplasin A
EGR1 early growth response 1
EIF3F eukaryotic translation initiation factor 3, subunit F
EML2 echinoderm microtubule associated protein like 2
FBRS fibrosin
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GLB1L galactosidase, beta 1-like
GLRA3 glycine receptor, alpha 3
GOLGA8A golgin A8 family, member A
HEATR6 HEAT repeat containing 6
HEMK1 HemK methyltransferase family member 1
HIST1H4B histone cluster 1, H4b
HOXB7 homeobox B7
HPR haptoglobin-related protein
IFI44 interferon-induced protein 44
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IL33 interleukin 33
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4
KCNK15 potassium channel, two pore domain subfamily K, member 15
KIAA1109 KIAA1109
KYNU kynureninase
LAMB4 laminin, beta 4
LOXL3 lysyl oxidase-like 3
LPPR4 lipid phosphate phosphatase-related protein type 4
MEF2D myocyte enhancer factor 2D
MEG3 maternally expressed 3 (non-protein coding)
METTL7A methyltransferase like 7A
MMP3 matrix metallopeptidase 3
MRAS muscle RAS oncogene homolog
MRC2 mannose receptor, C type 2
MST1 macrophage stimulating 1
N4BP2L2 NEDD4 binding protein 2-like 2
NF1 neurofibromin 1
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OASL 2'-5'-oligoadenylate synthetase-like
ONECUT2 one cut homeobox 2
OR10C1 olfactory receptor, family 10, subfamily C, member 1 (gene/pseudogene)
PCYT1A phosphate cytidylyltransferase 1, choline, alpha
PDE2A phosphodiesterase 2A, cGMP-stimulated
PDLIM7 PDZ and LIM domain 7 (enigma)
POM121 POM121 transmembrane nucleoporin
PPP1R2P9 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9
PTBP3 polypyrimidine tract binding protein 3
PVR poliovirus receptor
RAB11B RAB11B, member RAS oncogene family
RECQL5 RecQ protein-like 5
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
SCAND2P SCAN domain containing 2 pseudogene
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SLC22A14 solute carrier family 22, member 14
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SPRED2 sprouty-related, EVH1 domain containing 2
SUGP1 SURP and G patch domain containing 1
SYMPK symplekin
THOC5 THO complex 5
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TP53I11 tumor protein p53 inducible protein 11
TRIM29 tripartite motif containing 29
TTLL4 tubulin tyrosine ligase-like family member 4
TXK TXK tyrosine kinase
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WSB1 WD repeat and SOCS box containing 1
ZC2HC1C zinc finger, C2HC-type containing 1C
ZCCHC11 zinc finger, CCHC domain containing 11
ZNF268 zinc finger protein 268
ZNF440 zinc finger protein 440
ZNF471 zinc finger protein 471
ZNF710 zinc finger protein 710

decreased expression

Symbol Name
AFAP1 actin filament associated protein 1
ASAP1-IT1 ASAP1 intronic transcript 1
ATAD5 ATPase family, AAA domain containing 5
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
BATF3 basic leucine zipper transcription factor, ATF-like 3
C10ORF88 chromosome 10 open reading frame 88
C14ORF79 chromosome 14 open reading frame 79
C17ORF70 chromosome 17 open reading frame 70
CASP5 caspase 5, apoptosis-related cysteine peptidase
CASZ1 castor zinc finger 1
CATR1 CATR tumorigenicity conversion 1
CBX7 chromobox homolog 7
CD82 CD82 molecule
CENPO centromere protein O
CFAP45 cilia and flagella associated protein 45
CHMP6 charged multivesicular body protein 6
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CLCN6 chloride channel, voltage-sensitive 6
CNN1 calponin 1, basic, smooth muscle
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CORO1A coronin, actin binding protein, 1A
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DAGLA diacylglycerol lipase, alpha
DEF6 differentially expressed in FDCP 6 homolog (mouse)
EDAR ectodysplasin A receptor
EGR2 early growth response 2
EYA3 EYA transcriptional coactivator and phosphatase 3
FAM120C family with sequence similarity 120C
FGF23 fibroblast growth factor 23
FMO4 flavin containing monooxygenase 4
FZD7 frizzled class receptor 7
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GPC3 glypican 3
GPR1 G protein-coupled receptor 1
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8
HSPA1L heat shock 70kDa protein 1-like
IFT140 intraflagellar transport 140
IGFBP1 insulin-like growth factor binding protein 1
IL20RA interleukin 20 receptor, alpha
IL32 interleukin 32
INADL InaD-like (Drosophila)
IQSEC2 IQ motif and Sec7 domain 2
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KIAA1107 KIAA1107
KRT20 keratin 20, type I
KRT34 keratin 34, type I
LGALS4 lectin, galactoside-binding, soluble, 4
LMO7 LIM domain 7
LPAR4 lysophosphatidic acid receptor 4
LPAR6 lysophosphatidic acid receptor 6
LRP5L low density lipoprotein receptor-related protein 5-like
MAST3 microtubule associated serine/threonine kinase 3
MDFI MyoD family inhibitor
MED31 mediator complex subunit 31
METTL16 methyltransferase like 16
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
MRPL44 mitochondrial ribosomal protein L44
MTA2 metastasis associated 1 family, member 2
MTSS1L metastasis suppressor 1-like
NEUROD1 neuronal differentiation 1
NOL10 nucleolar protein 10
NPIPB15 nuclear pore complex interacting protein family, member B15
OCA2 oculocutaneous albinism II
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PBOV1 prostate and breast cancer overexpressed 1
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PLA2G1B phospholipase A2, group IB (pancreas)
PLD2 phospholipase D2
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
PRB3 proline-rich protein BstNI subfamily 3
PRKG2 protein kinase, cGMP-dependent, type II
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RUNDC3B RUN domain containing 3B
SEC14L2 SEC14-like 2 (S. cerevisiae)
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SPTBN2 spectrin, beta, non-erythrocytic 2
SYNPO synaptopodin
TAGLN transgelin
TBKBP1 TBK1 binding protein 1
TCEAL2 transcription elongation factor A (SII)-like 2
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TRAPPC13 trafficking protein particle complex 13
TSNAXIP1 translin-associated factor X interacting protein 1
ZNF286A zinc finger protein 286A
ZNF480 zinc finger protein 480
ZNF671 zinc finger protein 671
ZNF747 zinc finger protein 747