testicular germ cell cancer Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A testicular cancer that has_material_basis_in germ cells. (Human Disease Ontology, DOID_5557)
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Genes

102 genes co-occuring with the disease testicular germ cell cancer in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
GGN gametogenetin 1.31755
RNF4 ring finger protein 4 1.30969
AFP alpha-fetoprotein 1.27257
ATF7IP activating transcription factor 7 interacting protein 1.2717
DMRT1 doublesex and mab-3 related transcription factor 1 1.1588
RLN1 relaxin 1 1.02187
EBF3 early B-cell factor 3 0.978006
EBF2 early B-cell factor 2 0.929587
MAGEA4 melanoma antigen family A4 0.915963
RBMY1A1 RNA binding motif protein, Y-linked, family 1, member A1 0.899514
PIAS2 protein inhibitor of activated STAT, 2 0.818385
AR androgen receptor 0.807718
KITLG KIT ligand 0.799513
TRIM27 tripartite motif containing 27 0.746391
AHRR aryl-hydrocarbon receptor repressor 0.739082
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 0.730976
GFRA1 GDNF family receptor alpha 1 0.697911
BLMH bleomycin hydrolase 0.689092
ZFPM2 zinc finger protein, FOG family member 2 0.684692
DNMT3L DNA (cytosine-5-)-methyltransferase 3-like 0.679898
ALPPL2 alkaline phosphatase, placental-like 2 0.673518
ALPP alkaline phosphatase, placental 0.67312
ALPL alkaline phosphatase, liver/bone/kidney 0.672722
ESR2 estrogen receptor 2 (ER beta) 0.652089
PIAS1 protein inhibitor of activated STAT, 1 0.651694
PNMA2 paraneoplastic Ma antigen 2 0.641039
RBP2 retinol binding protein 2, cellular 0.638676
TGFBR3 transforming growth factor, beta receptor III 0.591337
TSPY1 testis specific protein, Y-linked 1 0.57305
CSH1 chorionic somatomammotropin hormone 1 (placental lactogen) 0.549359
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) 0.533475
CSH2 chorionic somatomammotropin hormone 2 0.528449
C5ORF38 chromosome 5 open reading frame 38 0.526904
TSPY10 testis specific protein, Y-linked 10 0.526518
TSPY3 testis specific protein, Y-linked 3 0.526518
SPRY4 sprouty homolog 4 (Drosophila) 0.509959
SP3 Sp3 transcription factor 0.509576
TNFRSF8 tumor necrosis factor receptor superfamily, member 8 0.501909
UPK3A uroplakin 3A 0.499614
LST1 leukocyte specific transcript 1 0.498467
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 0.494266
OR10A4 olfactory receptor, family 10, subfamily A, member 4 0.471468
KRT18 keratin 18, type I 0.468441
LHCGR luteinizing hormone/choriogonadotropin receptor 0.466928
EBF1 early B-cell factor 1 0.463149
DKK3 dickkopf WNT signaling pathway inhibitor 3 0.446935
INSL3 insulin-like 3 (Leydig cell) 0.438282
GATA6 GATA binding protein 6 0.428516
GP2 glycoprotein 2 (zymogen granule membrane) 0.413153
GPER1 G protein-coupled estrogen receptor 1 0.37592
TP53 tumor protein p53 0.37555
SFN stratifin 0.36704
AHR aryl hydrocarbon receptor 0.36704
CLPTM1L CLPTM1-like 0.356709
NR5A1 nuclear receptor subfamily 5, group A, member 1 0.338341
AMH anti-Mullerian hormone 0.307757
INHA inhibin, alpha 0.300533
CASP7 caspase 7, apoptosis-related cysteine peptidase 0.287952
RLN2 relaxin 2 0.28294
SELPLG selectin P ligand 0.280439
HPX hemopexin 0.280439
PER3 period circadian clock 3 0.270108
POLG polymerase (DNA directed), gamma 0.253831
RUNX3 runt-related transcription factor 3 0.243645
OR4F29 olfactory receptor, family 4, subfamily F, member 29 0.222822
KRT7 keratin 7, type II 0.21974
HLA-G major histocompatibility complex, class I, G 0.211597
GATA4 GATA binding protein 4 0.210253
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 0.209918
ALB albumin 0.208579
RXFP1 relaxin/insulin-like family peptide receptor 1 0.204923
GSTM2 glutathione S-transferase mu 2 (muscle) 0.20229
GPC3 glypican 3 0.188022
BMP7 bone morphogenetic protein 7 0.18151
TIA1 TIA1 cytotoxic granule-associated RNA binding protein 0.179802
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.17952
SP1 Sp1 transcription factor 0.177029
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 0.162707
APC adenomatous polyposis coli 0.162707
HPGDS hematopoietic prostaglandin D synthase 0.158605
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.150589
FASLG Fas ligand (TNF superfamily, member 6) 0.142001
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 0.141554
PIDD1 p53-induced death domain protein 1 0.139539
AHSG alpha-2-HS-glycoprotein 0.139454
ENO2 enolase 2 (gamma, neuronal) 0.137258
TF transferrin 0.137035
LCK LCK proto-oncogene, Src family tyrosine kinase 0.135153
PTPRC protein tyrosine phosphatase, receptor type, C 0.133189
TJP1 tight junction protein 1 0.132278
ZNF135 zinc finger protein 135 0.126546
KRT20 keratin 20, type I 0.121175
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.106715
GFAP glial fibrillary acidic protein 0.099493
HP haptoglobin 0.093622
HPR haptoglobin-related protein 0.093043
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.091619
PLAU plasminogen activator, urokinase 0.090057
TTR transthyretin 0.087469
APOA1 apolipoprotein A-I 0.085126
CD44 CD44 molecule (Indian blood group) 0.08237
B2M beta-2-microglobulin 0.08099