testicular disease Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
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Genes

226 genes co-occuring with the disease testicular disease in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
AR androgen receptor 3.059
SRY sex determining region Y 1.60726
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) 1.3904
HSD17B1P1 hydroxysteroid (17-beta) dehydrogenase 1 pseudogene 1 1.36727
HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3 1.25733
RNASE10 ribonuclease, RNase A family, 10 (non-active) 1.12319
PRKY protein kinase, Y-linked, pseudogene 1.0362
AMH anti-Mullerian hormone 1.00752
SOX9 SRY (sex determining region Y)-box 9 0.975482
PRKX protein kinase, X-linked 0.949519
STK19 serine/threonine kinase 19 0.93497
SHBG sex hormone-binding globulin 0.899924
DBT dihydrolipoamide branched chain transacylase E2 0.897872
NR5A1 nuclear receptor subfamily 5, group A, member 1 0.888438
NCOA2 nuclear receptor coactivator 2 0.88475
SPATA7 spermatogenesis associated 7 0.881472
MAMLD1 mastermind-like domain containing 1 0.874509
CAT catalase 0.854859
GJB6 gap junction protein, beta 6, 30kDa 0.831099
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 0.826178
ZFY zinc finger protein, Y-linked 0.821257
EDA ectodysplasin A 0.813873
SOD2 superoxide dismutase 2, mitochondrial 0.800333
NOS3 nitric oxide synthase 3 (endothelial cell) 0.792541
GGN gametogenetin 0.776568
CRISP2 cysteine-rich secretory protein 2 0.771661
INSL3 insulin-like 3 (Leydig cell) 0.760639
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 0.74761
INHA inhibin, alpha 0.746391
CD4 CD4 molecule 0.720865
GPX4 glutathione peroxidase 4 0.694301
KIF1C kinesin family member 1C 0.678302
ZFX zinc finger protein, X-linked 0.66755
GPX5 glutathione peroxidase 5 0.660008
GPX1 glutathione peroxidase 1 0.640645
FASLG Fas ligand (TNF superfamily, member 6) 0.631205
KIF21B kinesin family member 21B 0.626495
IKZF3 IKAROS family zinc finger 3 (Aiolos) 0.615138
DNTT DNA nucleotidylexotransferase 0.597571
NAP1L2 nucleosome assembly protein 1-like 2 0.573439
IFNA2 interferon, alpha 2 0.560616
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6 0.55945
IL12A interleukin 12A 0.549747
ZAN zonadhesin (gene/pseudogene) 0.546256
SCUBE1 signal peptide, CUB domain, EGF-like 1 0.530768
TSPY1 testis specific protein, Y-linked 1 0.529994
SPAG11A sperm associated antigen 11A 0.499997
KAT7 K(lysine) acetyltransferase 7 0.493885
TSPY3 testis specific protein, Y-linked 3 0.483985
TSPY10 testis specific protein, Y-linked 10 0.483985
PSMG3 proteasome (prosome, macropain) assembly chaperone 3 0.481325
UCHL5 ubiquitin carboxyl-terminal hydrolase L5 0.480566
SPAG11B sperm associated antigen 11B 0.465038
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2 0.462016
POMC proopiomelanocortin 0.460129
DHDH dihydrodiol dehydrogenase (dimeric) 0.450701
CATSPER1 cation channel, sperm associated 1 0.443171
CLDN11 claudin 11 0.442042
HARS histidyl-tRNA synthetase 0.438282
TADA3 transcriptional adaptor 3 0.436026
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) 0.431144
GGPS1 geranylgeranyl diphosphate synthase 1 0.429266
NNT nicotinamide nucleotide transhydrogenase 0.42739
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.42589
VARS valyl-tRNA synthetase 0.418394
CCT4 chaperonin containing TCP1, subunit 4 (delta) 0.41465
AFP alpha-fetoprotein 0.399334
ECEL1 endothelin converting enzyme-like 1 0.385565
CIRBP cold inducible RNA binding protein 0.384822
BBS9 Bardet-Biedl syndrome 9 0.383708
ESR1 estrogen receptor 1 0.374809
LHCGR luteinizing hormone/choriogonadotropin receptor 0.374809
MPO myeloperoxidase 0.370368
APOD apolipoprotein D 0.359289
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.356341
GP2 glycoprotein 2 (zymogen granule membrane) 0.354868
CSNK2B casein kinase 2, beta polypeptide 0.349349
ATAD3C ATPase family, AAA domain containing 3C 0.338707
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) 0.335412
TBPL1 TBP-like 1 0.332121
BAX BCL2-associated X protein 0.313189
ALPPL2 alkaline phosphatase, placental-like 2 0.311014
ALPP alkaline phosphatase, placental 0.310652
ALPL alkaline phosphatase, liver/bone/kidney 0.309928
CRP C-reactive protein, pentraxin-related 0.304864
RXFP2 relaxin/insulin-like family peptide receptor 2 0.299092
ADM2 adrenomedullin 2 0.290462
HDC histidine decarboxylase 0.28151
SLC6A7 solute carrier family 6 (neurotransmitter transporter), member 7 0.280439
AQP9 aquaporin 9 0.272597
SKI SKI proto-oncogene 0.267977
ARSE arylsulfatase E (chondrodysplasia punctata 1) 0.261952
HRH1 histamine receptor H1 0.257005
PRM1 protamine 1 0.247852
AMHR2 anti-Mullerian hormone receptor, type II 0.243295
FOXP3 forkhead box P3 0.241196
TNF tumor necrosis factor 0.240847
BEST1 bestrophin 1 0.240497
DMRT1 doublesex and mab-3 related transcription factor 1 0.240497
LATS1 large tumor suppressor kinase 1 0.23666
CUL4A cullin 4A 0.233183
ARAF A-Raf proto-oncogene, serine/threonine kinase 0.223853
HSPA1L heat shock 70kDa protein 1-like 0.221108
NR0B1 nuclear receptor subfamily 0, group B, member 1 0.219057
TRDN triadin 0.215314
CD79A CD79a molecule, immunoglobulin-associated alpha 0.215314
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 0.214975
RAMP2 receptor (G protein-coupled) activity modifying protein 2 0.209583
IL2 interleukin 2 0.198709
ALB albumin 0.195183
ZP3 zona pellucida glycoprotein 3 (sperm receptor) 0.194865
CREM cAMP responsive element modulator 0.192971
KIF5A kinesin family member 5A 0.192344
MEA1 male-enhanced antigen 1 0.187113
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 0.18651
CTRL chymotrypsin-like 0.18621
SLK STE20-like kinase 0.185016
ATL1 atlastin GTPase 1 0.184128
FLOT1 flotillin 1 0.183835
TNC tenascin C 0.182375
SET SET nuclear proto-oncogene 0.180084
PIAS3 protein inhibitor of activated STAT, 3 0.179802
CCR2 chemokine (C-C motif) receptor 2 0.177576
HIST2H2AC histone cluster 2, H2ac 0.175947
HIST2H2AA4 histone cluster 2, H2aa4 0.175679
HIST2H2AA3 histone cluster 2, H2aa3 0.175679
BMP1 bone morphogenetic protein 1 0.175411
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.168381
IGF1 insulin-like growth factor 1 (somatomedin C) 0.166995
APAF1 apoptotic peptidase activating factor 1 0.166544
MAPK3 mitogen-activated protein kinase 3 0.166095
PGK1 phosphoglycerate kinase 1 0.165655
TADA1 transcriptional adaptor 1 0.165217
HOXA5 homeobox A5 0.164786
ACR acrosin 0.162306
HSPE1 heat shock 10kDa protein 1 0.161523
PREB prolactin regulatory element binding 0.160203
IL6 interleukin 6 0.159838
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) 0.159302
POLI polymerase (DNA directed) iota 0.158266
TNNI1 troponin I type 1 (skeletal, slow) 0.140684
TNNI2 troponin I type 2 (skeletal, fast) 0.139817
NQO1 NAD(P)H dehydrogenase, quinone 1 0.138896
PHYH phytanoyl-CoA 2-hydroxylase 0.13758
HBD hemoglobin, delta 0.132882
CSN1S1 casein alpha s1 0.131889
PTPRC protein tyrosine phosphatase, receptor type, C 0.131159
HBB hemoglobin, beta 0.130104
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 0.126894
CAST calpastatin 0.125332
ATF2 activating transcription factor 2 0.124665
OR6B2 olfactory receptor, family 6, subfamily B, member 2 0.123529
CD86 CD86 molecule 0.123407
PDIA3 protein disulfide isomerase family A, member 3 0.122952
ECI1 enoyl-CoA delta isomerase 1 0.121604
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 0.121604
PROS1 protein S (alpha) 0.121491
CCL2 chemokine (C-C motif) ligand 2 0.121401
SCAI suppressor of cancer cell invasion 0.121194
HMOX1 heme oxygenase 1 0.120442
OR10R2 olfactory receptor, family 10, subfamily R, member 2 0.119186
THY1 Thy-1 cell surface antigen 0.11916
NOVA2 neuro-oncological ventral antigen 2 0.119006
PRDX6 peroxiredoxin 6 0.118118
CD80 CD80 molecule 0.117907
NLE1 notchless homolog 1 (Drosophila) 0.117853
JMJD6 jumonji domain containing 6 0.116776
CAPN2 calpain 2, (m/II) large subunit 0.116663
DDB1 damage-specific DNA binding protein 1, 127kDa 0.116578
JUN jun proto-oncogene 0.116409
OCLN occludin 0.116381
SH3BP5 SH3-domain binding protein 5 (BTK-associated) 0.116295
MEGF6 multiple EGF-like-domains 6 0.115945
CD68 CD68 molecule 0.115887
STAT2 signal transducer and activator of transcription 2, 113kDa 0.115829
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 0.114511
SELE selectin E 0.113984
MEFV Mediterranean fever 0.113953
CD8B CD8b molecule 0.113383
C1R complement component 1, r subcomponent 0.112999
SGK1 serum/glucocorticoid regulated kinase 1 0.112805
CRLF1 cytokine receptor-like factor 1 0.112772
IL23A interleukin 23, alpha subunit p19 0.112673
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 0.112343
CYBB cytochrome b-245, beta polypeptide 0.112179
TGM4 transglutaminase 4 0.111947
IL1A interleukin 1, alpha 0.111031
PPARD peroxisome proliferator-activated receptor delta 0.110403
HSPA4 heat shock 70kDa protein 4 0.110298
GJA1 gap junction protein, alpha 1, 43kDa 0.110017
CYLD cylindromatosis (turban tumor syndrome) 0.109981
HAND2 heart and neural crest derivatives expressed 2 0.109874
ADORA2A adenosine A2a receptor 0.109084
HLA-B major histocompatibility complex, class I, B 0.10853
F8 coagulation factor VIII, procoagulant component 0.108272
PON3 paraoxonase 3 0.10805
GUSB glucuronidase, beta 0.10805
SLPI secretory leukocyte peptidase inhibitor 0.108012
GSR glutathione reductase 0.107746
FHL1 four and a half LIM domains 1 0.107595
IL22 interleukin 22 0.107557
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein 0.10691
TNFRSF4 tumor necrosis factor receptor superfamily, member 4 0.106754
ICAM1 intercellular adhesion molecule 1 0.106598
POU5F1B POU class 5 homeobox 1B 0.105776
MAPK8 mitogen-activated protein kinase 8 0.105696
CCL3 chemokine (C-C motif) ligand 3 0.104407
MAPK1 mitogen-activated protein kinase 1 0.10416
TLR1 toll-like receptor 1 0.103996
C1S complement component 1, s subcomponent 0.103332
IGFBP5 insulin-like growth factor binding protein 5 0.103122
IFNA21 interferon, alpha 21 0.102786
TBX3 T-box 3 0.102449
IVD isovaleryl-CoA dehydrogenase 0.102319
ESR2 estrogen receptor 2 (ER beta) 0.102061
CD44 CD44 molecule (Indian blood group) 0.101544
SCARB1 scavenger receptor class B, member 1 0.101544
IFNA17 interferon, alpha 17 0.100272
TP63 tumor protein p63 0.099781
CD209 CD209 molecule 0.099284
CHEK2 checkpoint kinase 2 0.099059
F2RL1 coagulation factor II (thrombin) receptor-like 1 0.097866
HLA-E major histocompatibility complex, class I, E 0.097262
PI3 peptidase inhibitor 3, skin-derived 0.096697
FLT1 fms-related tyrosine kinase 1 0.096509
POU5F1 POU class 5 homeobox 1 0.095506