tertiary granule Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A secretory granule that contains cathepsin and gelatinase and is readily exocytosed upon cell activation; found primarily in mature neutrophil cells. (Gene Ontology, GO_0070820)
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Genes

62 proteins co-occuring with the tertiary granule cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon 1.48758
LTF lactotransferrin 1.21428
PDXP pyridoxal (pyridoxine, vitamin B6) phosphatase 1.04582
MMP9 matrix metallopeptidase 9 0.864907
MPO myeloperoxidase 0.841023
STX4 syntaxin 4 0.829548
CXCR1 chemokine (C-X-C motif) receptor 1 0.793313
ABR active BCR-related 0.765893
STXBP3 syntaxin binding protein 3 0.75181
PTPN9 protein tyrosine phosphatase, non-receptor type 9 0.684644
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 0.662072
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.647862
MMP8 matrix metallopeptidase 8 0.644429
STX11 syntaxin 11 0.617557
NSF N-ethylmaleimide-sensitive factor 0.609932
STXBP2 syntaxin binding protein 2 0.602331
SELL selectin L 0.565923
CXCR2 chemokine (C-X-C motif) receptor 2 0.553078
UNC13D unc-13 homolog D (C. elegans) 0.501476
PGLYRP1 peptidoglycan recognition protein 1 0.469203
CD63 CD63 molecule 0.45641
STX7 syntaxin 7 0.447656
PYCARD PYD and CARD domain containing 0.445275
ANXA3 annexin A3 0.430647
RAB27A RAB27A, member RAS oncogene family 0.40675
SLC34A1 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1 0.393162
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1 0.392388
ZNF436 zinc finger protein 436 0.386593
USE1 unconventional SNARE in the ER 1 homolog (S. cerevisiae) 0.386593
RAB27B RAB27B, member RAS oncogene family 0.371216
CSF3R colony stimulating factor 3 receptor (granulocyte) 0.365859
GFI1 growth factor independent 1 transcription repressor 0.361659
CXCL8 chemokine (C-X-C motif) ligand 8 0.356324
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 0.336996
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 0.335864
AIM2 absent in melanoma 2 0.326829
FPR2 formyl peptide receptor 2 0.326078
FGR FGR proto-oncogene, Src family tyrosine kinase 0.323075
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) 0.320451
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 0.313344
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1) 0.308867
SRGN serglycin 0.286614
UMOD uromodulin 0.265311
BPI bactericidal/permeability-increasing protein 0.26385
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 0.255834
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 0.250751
STX3 syntaxin 3 0.245685
ACPP acid phosphatase, prostate 0.23776
EPX eosinophil peroxidase 0.236324
STX6 syntaxin 6 0.224204
MEFV Mediterranean fever 0.21681
LCN2 lipocalin 2 0.21646
ACP2 acid phosphatase 2, lysosomal 0.214366
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 0.197993
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 0.179459
HPSE heparanase 0.179459
ALLC allantoicase 0.166405
CAMP cathelicidin antimicrobial peptide 0.16298
VAMP3 vesicle-associated membrane protein 3 0.162546
ALPPL2 alkaline phosphatase, placental-like 2 0.161275
ALPL alkaline phosphatase, liver/bone/kidney 0.161068
ALPP alkaline phosphatase, placental 0.160863