tert-Butylhydroperoxide Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
Description An alkyl hydroperoxide in which the alkyl group is tert-butyl. It is widely used in a variety of oxidation processes. (Chemical Entities of Biological Interest Ontology, CHEBI_64090)
External Link http://ctdbase.org/detail.go?type=chem&acc=D020122
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Genes

129 genes/proteins interacting with the chemical tert-Butylhydroperoxide from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ACHE acetylcholinesterase (Yt blood group)
ALAS1 5'-aminolevulinate synthase 1
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
APAF1 apoptotic peptidase activating factor 1
APOE apolipoprotein E
AQP4 aquaporin 4
ASS1 argininosuccinate synthase 1
ATXN1 ataxin 1
BAD BCL2-associated agonist of cell death
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
CAPN1 calpain 1, (mu/I) large subunit
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CAT catalase
CCNE1 cyclin E1
CD68 CD68 molecule
CDK2 cyclin-dependent kinase 2
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
COMT catechol-O-methyltransferase
CREB1 cAMP responsive element binding protein 1
CRYZ crystallin, zeta (quinone reductase)
CSF1 colony stimulating factor 1 (macrophage)
CTH cystathionine gamma-lyase
CXCL8 chemokine (C-X-C motif) ligand 8
CYCS cytochrome c, somatic
DDIT3 DNA-damage-inducible transcript 3
ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial
EEF2 eukaryotic translation elongation factor 2
EPB42 erythrocyte membrane protein band 4.2
ERN1 endoplasmic reticulum to nucleus signaling 1
ETFA electron-transfer-flavoprotein, alpha polypeptide
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase)
G6PD glucose-6-phosphate dehydrogenase
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GCLC glutamate-cysteine ligase, catalytic subunit
GCLM glutamate-cysteine ligase, modifier subunit
GFAP glial fibrillary acidic protein
GJB2 gap junction protein, beta 2, 26kDa
GLRX glutaredoxin (thioltransferase)
GOT1 glutamic-oxaloacetic transaminase 1, soluble
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GPX1 glutathione peroxidase 1
GPX2 glutathione peroxidase 2
GPX4 glutathione peroxidase 4
GSR glutathione reductase
GSTA2 glutathione S-transferase alpha 2
GSTA3 glutathione S-transferase alpha 3
GSTM2 glutathione S-transferase mu 2 (muscle)
GSTM5 glutathione S-transferase mu 5
GSTT1 glutathione S-transferase theta 1
GSTZ1 glutathione S-transferase zeta 1
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HEPH hephaestin
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HMOX1 heme oxygenase 1
HMOX2 heme oxygenase 2
HSPB1 heat shock 27kDa protein 1
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IL11 interleukin 11
IL1B interleukin 1, beta
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1
LYPLA1 lysophospholipase I
MAP2K3 mitogen-activated protein kinase kinase 3
MAP2K4 mitogen-activated protein kinase kinase 4
MAP2K6 mitogen-activated protein kinase kinase 6
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPK9 mitogen-activated protein kinase 9
MCL1 myeloid cell leukemia 1
MGST2 microsomal glutathione S-transferase 2
MSRA methionine sulfoxide reductase A
MSRB1 methionine sulfoxide reductase B1
MSRB2 methionine sulfoxide reductase B2
MSRB3 methionine sulfoxide reductase B3
MT2A metallothionein 2A
MTF1 metal-regulatory transcription factor 1
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NMNAT3 nicotinamide nucleotide adenylyltransferase 3
ODC1 ornithine decarboxylase 1
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PARP1 poly (ADP-ribose) polymerase 1
PPARG peroxisome proliferator-activated receptor gamma
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PRDX1 peroxiredoxin 1
PRDX2 peroxiredoxin 2
PRDX3 peroxiredoxin 3
PRDX6 peroxiredoxin 6
PRKCA protein kinase C, alpha
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RETSAT retinol saturase (all-trans-retinol 13,14-reductase)
RGN regucalcin
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RXRA retinoid X receptor, alpha
SEPP1 selenoprotein P, plasma, 1
SIRT1 sirtuin 1
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
SLPI secretory leukocyte peptidase inhibitor
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
SORD sorbitol dehydrogenase
SPTA1 spectrin, alpha, erythrocytic 1
SPTB spectrin, beta, erythrocytic
TGFB1 transforming growth factor, beta 1
TJP1 tight junction protein 1
TNF tumor necrosis factor
TP53 tumor protein p53
TRAF2 TNF receptor-associated factor 2
TSHB thyroid stimulating hormone, beta
TUBA1B tubulin, alpha 1b
TXN thioredoxin
TXN2 thioredoxin 2
TXNIP thioredoxin interacting protein
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
VEGFA vascular endothelial growth factor A
VEGFC vascular endothelial growth factor C
VIM vimentin