terguride-4633 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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193 genes differentially expressed following the terguride-4633 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGB androglobin
ADGRD2 adhesion G protein-coupled receptor D2
AFF1 AF4/FMR2 family, member 1
AFF4 AF4/FMR2 family, member 4
ALK anaplastic lymphoma receptor tyrosine kinase
APC adenomatous polyposis coli
ARHGAP28 Rho GTPase activating protein 28
ARHGAP35 Rho GTPase activating protein 35
ARTN artemin
BCL6 B-cell CLL/lymphoma 6
C11ORF16 chromosome 11 open reading frame 16
C7ORF26 chromosome 7 open reading frame 26
CA5B carbonic anhydrase VB, mitochondrial
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCKAR cholecystokinin A receptor
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CDC25C cell division cycle 25C
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CELA2A chymotrypsin-like elastase family, member 2A
CENPI centromere protein I
CNKSR2 connector enhancer of kinase suppressor of Ras 2
CSDC2 cold shock domain containing C2, RNA binding
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
CYP4F8 cytochrome P450, family 4, subfamily F, polypeptide 8
DBT dihydrolipoamide branched chain transacylase E2
EPHA7 EPH receptor A7
ETV1 ets variant 1
EXO5 exonuclease 5
EYA4 EYA transcriptional coactivator and phosphatase 4
FBXL7 F-box and leucine-rich repeat protein 7
FCF1 FCF1 rRNA-processing protein
FKBP10 FK506 binding protein 10, 65 kDa
FLT3LG fms-related tyrosine kinase 3 ligand
FOS FBJ murine osteosarcoma viral oncogene homolog
FRMD4B FERM domain containing 4B
FRS2 fibroblast growth factor receptor substrate 2
FYB FYN binding protein
GCNT4 glucosaminyl (N-acetyl) transferase 4, core 2
GPR135 G protein-coupled receptor 135
GRIA3 glutamate receptor, ionotropic, AMPA 3
GRK4 G protein-coupled receptor kinase 4
GZMK granzyme K (granzyme 3; tryptase II)
HES2 hes family bHLH transcription factor 2
HIPK3 homeodomain interacting protein kinase 3
HLF hepatic leukemia factor
HMOX1 heme oxygenase 1
HOXB2 homeobox B2
HOXC13 homeobox C13
HOXC4 homeobox C4
HTR3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
IL4 interleukin 4
IL6 interleukin 6
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MVB12B multivesicular body subunit 12B
N4BP2L2 NEDD4 binding protein 2-like 2
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PCYT1A phosphate cytidylyltransferase 1, choline, alpha
PDE4DIP phosphodiesterase 4D interacting protein
PHLDB1 pleckstrin homology-like domain, family B, member 1
PIGO phosphatidylinositol glycan anchor biosynthesis, class O
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PKD2L2 polycystic kidney disease 2-like 2
PLA2G3 phospholipase A2, group III
PLK4 polo-like kinase 4
POM121 POM121 transmembrane nucleoporin
PRKG1 protein kinase, cGMP-dependent, type I
R3HCC1L R3H domain and coiled-coil containing 1-like
RAB35 RAB35, member RAS oncogene family
RFXAP regulatory factor X-associated protein
RGS5 regulator of G-protein signaling 5
RHO rhodopsin
RNF6 ring finger protein (C3H2C3 type) 6
RRAGD Ras-related GTP binding D
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCYL2 SCY1-like 2 (S. cerevisiae)
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2
SGK2 serum/glucocorticoid regulated kinase 2
SIGLEC8 sialic acid binding Ig-like lectin 8
SOCS3 suppressor of cytokine signaling 3
SPI1 Spi-1 proto-oncogene
SRSF1 serine/arginine-rich splicing factor 1
SUGP1 SURP and G patch domain containing 1
TAPBP TAP binding protein (tapasin)
THSD7A thrombospondin, type I, domain containing 7A
TMF1 TATA element modulatory factor 1
TRIM29 tripartite motif containing 29
TUBGCP2 tubulin, gamma complex associated protein 2
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked
VCX2 variable charge, X-linked 2
ZHX3 zinc fingers and homeoboxes 3
ZNF675 zinc finger protein 675

decreased expression

Symbol Name
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ALG12 ALG12, alpha-1,6-mannosyltransferase
ALPK1 alpha-kinase 1
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANKRD40 ankyrin repeat domain 40
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
ASAP1-IT1 ASAP1 intronic transcript 1
ASTN1 astrotactin 1
C5ORF45 chromosome 5 open reading frame 45
C7ORF69 chromosome 7 open reading frame 69
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CD79A CD79a molecule, immunoglobulin-associated alpha
CGA glycoprotein hormones, alpha polypeptide
CHRDL1 chordin-like 1
CIDEB cell death-inducing DFFA-like effector b
CIDEC cell death-inducing DFFA-like effector c
COL9A3 collagen, type IX, alpha 3
COMP cartilage oligomeric matrix protein
CREB5 cAMP responsive element binding protein 5
CSAD cysteine sulfinic acid decarboxylase
CTSK cathepsin K
DNM3 dynamin 3
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ERO1LB ERO1-like beta (S. cerevisiae)
FAM110B family with sequence similarity 110, member B
FSTL3 follistatin-like 3 (secreted glycoprotein)
GAR1 GAR1 ribonucleoprotein
GPR3 G protein-coupled receptor 3
GRAMD1C GRAM domain containing 1C
GSTA3 glutathione S-transferase alpha 3
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HDAC11 histone deacetylase 11
HDAC7 histone deacetylase 7
HIST1H3I histone cluster 1, H3i
HOXC8 homeobox C8
HSPA1L heat shock 70kDa protein 1-like
IGKV3-20 immunoglobulin kappa variable 3-20
KIAA0513 KIAA0513
KIAA0922 KIAA0922
KIAA1456 KIAA1456
KLHL36 kelch-like family member 36
KRTAP1-3 keratin associated protein 1-3
LIMS2 LIM and senescent cell antigen-like domains 2
LINC00341 long intergenic non-protein coding RNA 341
LINC00597 long intergenic non-protein coding RNA 597
LOC100129648 uncharacterized LOC100129648
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LRP5L low density lipoprotein receptor-related protein 5-like
MAP3K7CL MAP3K7 C-terminal like
MBTD1 mbt domain containing 1
MFSD11 major facilitator superfamily domain containing 11
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MRPL41 mitochondrial ribosomal protein L41
NCS1 neuronal calcium sensor 1
NEUROD1 neuronal differentiation 1
NNAT neuronatin
NPFFR1 neuropeptide FF receptor 1
NR1H4 nuclear receptor subfamily 1, group H, member 4
NRN1 neuritin 1
NTF3 neurotrophin 3
NYNRIN NYN domain and retroviral integrase containing
OLFM4 olfactomedin 4
OR1G1 olfactory receptor, family 1, subfamily G, member 1
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PARM1 prostate androgen-regulated mucin-like protein 1
PDE8B phosphodiesterase 8B
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLD2 phospholipase D2
PODXL2 podocalyxin-like 2
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRR15L proline rich 15-like
PXMP4 peroxisomal membrane protein 4, 24kDa
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
SCARA3 scavenger receptor class A, member 3
SCIN scinderin
SCN1B sodium channel, voltage gated, type I beta subunit
SFRP5 secreted frizzled-related protein 5
SKI SKI proto-oncogene
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SLN sarcolipin
SPINK1 serine peptidase inhibitor, Kazal type 1
STAG3L4 stromal antigen 3-like 4 (pseudogene)
SYNGR3 synaptogyrin 3
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TM7SF3 transmembrane 7 superfamily member 3
TMEM209 transmembrane protein 209
TSNAXIP1 translin-associated factor X interacting protein 1
TSPAN2 tetraspanin 2
USP20 ubiquitin specific peptidase 20
VWA1 von Willebrand factor A domain containing 1
ZFP30 ZFP30 zinc finger protein
ZNF137P zinc finger protein 137, pseudogene
ZNF230 zinc finger protein 230
ZNF571 zinc finger protein 571
ZSCAN2 zinc finger and SCAN domain containing 2