terguride-3082 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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196 genes differentially expressed following the terguride-3082 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ABHD2 abhydrolase domain containing 2
ACVR1B activin A receptor, type IB
AJAP1 adherens junctions associated protein 1
AKAP4 A kinase (PRKA) anchor protein 4
ALOX5 arachidonate 5-lipoxygenase
ARHGAP26 Rho GTPase activating protein 26
ARHGAP35 Rho GTPase activating protein 35
ARMC9 armadillo repeat containing 9
BARX1 BARX homeobox 1
BMP1 bone morphogenetic protein 1
BPI bactericidal/permeability-increasing protein
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
C11ORF16 chromosome 11 open reading frame 16
C1ORF68 chromosome 1 open reading frame 68
C22ORF24 chromosome 22 open reading frame 24
CACNB4 calcium channel, voltage-dependent, beta 4 subunit
CALCRL calcitonin receptor-like
CALML3 calmodulin-like 3
CBR3 carbonyl reductase 3
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
CLCN7 chloride channel, voltage-sensitive 7
CLIP2 CAP-GLY domain containing linker protein 2
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2
COL15A1 collagen, type XV, alpha 1
COL1A1 collagen, type I, alpha 1
CPB2 carboxypeptidase B2 (plasma)
CPT1A carnitine palmitoyltransferase 1A (liver)
CSPG4 chondroitin sulfate proteoglycan 4
DAAM2 dishevelled associated activator of morphogenesis 2
DEPTOR DEP domain containing MTOR-interacting protein
DKFZP434C153 DKFZP434C153 protein
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
EPS8L1 EPS8-like 1
FAM149A family with sequence similarity 149, member A
FAS Fas cell surface death receptor
FER1L4 fer-1-like family member 4, pseudogene (functional)
FOSL2 FOS-like antigen 2
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GLRX3 glutaredoxin 3
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GOSR2 golgi SNAP receptor complex member 2
GPC1 glypican 1
GPR107 G protein-coupled receptor 107
GPR15 G protein-coupled receptor 15
GSTA3 glutathione S-transferase alpha 3
GUCY1A2 guanylate cyclase 1, soluble, alpha 2
HEXIM1 hexamethylene bis-acetamide inducible 1
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
ICA1 islet cell autoantigen 1, 69kDa
ITGB1BP2 integrin beta 1 binding protein (melusin) 2
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3
KDM4C lysine (K)-specific demethylase 4C
KDM8 lysine (K)-specific demethylase 8
KRT81 keratin 81, type II
MAGEA5 melanoma antigen family A5
MARCKS myristoylated alanine-rich protein kinase C substrate
MCM3AP minichromosome maintenance complex component 3 associated protein
MMP1 matrix metallopeptidase 1
MUC3A mucin 3A, cell surface associated
MUC5B mucin 5B, oligomeric mucus/gel-forming
NEBL nebulette
NR2F2 nuclear receptor subfamily 2, group F, member 2
NRP1 neuropilin 1
OMG oligodendrocyte myelin glycoprotein
PCLO piccolo presynaptic cytomatrix protein
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLD2 phospholipase D2
POU2F2 POU class 2 homeobox 2
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PRB3 proline-rich protein BstNI subfamily 3
PRSS8 protease, serine, 8
PTCRA pre T-cell antigen receptor alpha
RRBP1 ribosome binding protein 1
RUSC2 RUN and SH3 domain containing 2
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SIN3B SIN3 transcription regulator family member B
SLC34A1 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
SOCS2 suppressor of cytokine signaling 2
SOCS7 suppressor of cytokine signaling 7
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
STS steroid sulfatase (microsomal), isozyme S
STX5 syntaxin 5
SYNDIG1 synapse differentiation inducing 1
SYTL2 synaptotagmin-like 2
TLX2 T-cell leukemia homeobox 2
TMEM2 transmembrane protein 2
TRPC6 transient receptor potential cation channel, subfamily C, member 6
USP53 ubiquitin specific peptidase 53
VCX2 variable charge, X-linked 2
ZFHX4 zinc finger homeobox 4
ZNF518A zinc finger protein 518A
ZSCAN18 zinc finger and SCAN domain containing 18

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ADTRP androgen-dependent TFPI-regulating protein
AEN apoptosis enhancing nuclease
ALKBH1 alkB, alkylation repair homolog 1 (E. coli)
ANXA2P3 annexin A2 pseudogene 3
AP1B1 adaptor-related protein complex 1, beta 1 subunit
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
ARRB1 arrestin, beta 1
ART1 ADP-ribosyltransferase 1
BAHD1 bromo adjacent homology domain containing 1
BTF3P12 basic transcription factor 3 pseudogene 12
BTNL3 butyrophilin-like 3
C17ORF53 chromosome 17 open reading frame 53
CAMK4 calcium/calmodulin-dependent protein kinase IV
CCDC85C coiled-coil domain containing 85C
CD70 CD70 molecule
CDKL3 cyclin-dependent kinase-like 3
CIDEC cell death-inducing DFFA-like effector c
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
CORT cortistatin
CPTP ceramide-1-phosphate transfer protein
DENND5B DENN/MADD domain containing 5B
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DUSP8 dual specificity phosphatase 8
ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 (putative)
EPHB6 EPH receptor B6
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM135A family with sequence similarity 135, member A
FBRS fibrosin
FGL1 fibrinogen-like 1
FKBP9 FK506 binding protein 9, 63 kDa
FLRT1 fibronectin leucine rich transmembrane protein 1
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GSTA4 glutathione S-transferase alpha 4
HIST1H2BJ histone cluster 1, H2bj
HIST1H3G histone cluster 1, H3g
HRAS Harvey rat sarcoma viral oncogene homolog
IFNAR1 interferon (alpha, beta and omega) receptor 1
INF2 inverted formin, FH2 and WH2 domain containing
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
ITGA10 integrin, alpha 10
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KIAA0355 KIAA0355
KLHL26 kelch-like family member 26
LOXL3 lysyl oxidase-like 3
LPPR1 lipid phosphate phosphatase-related protein type 1
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LTC4S leukotriene C4 synthase
MCTP2 multiple C2 domains, transmembrane 2
MED15 mediator complex subunit 15
MKRN3 makorin ring finger protein 3
MRAS muscle RAS oncogene homolog
MX2 MX dynamin-like GTPase 2
NACA2 nascent polypeptide-associated complex alpha subunit 2
NCS1 neuronal calcium sensor 1
NINJ2 ninjurin 2
NIPAL2 NIPA-like domain containing 2
NT5DC3 5'-nucleotidase domain containing 3
PARP16 poly (ADP-ribose) polymerase family, member 16
PDGFD platelet derived growth factor D
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PMFBP1 polyamine modulated factor 1 binding protein 1
POMZP3 POM121 and ZP3 fusion
PPDPF pancreatic progenitor cell differentiation and proliferation factor
PYGB phosphorylase, glycogen; brain
RNF122 ring finger protein 122
RNF25 ring finger protein 25
RRAGB Ras-related GTP binding B
SCN10A sodium channel, voltage gated, type X alpha subunit
SETD1A SET domain containing 1A
SHPK sedoheptulokinase
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC10A3 solute carrier family 10, member 3
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLITRK5 SLIT and NTRK-like family, member 5
SOX12 SRY (sex determining region Y)-box 12
SP140 SP140 nuclear body protein
SPI1 Spi-1 proto-oncogene
SRR serine racemase
ST7L suppression of tumorigenicity 7 like
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
STX1A syntaxin 1A (brain)
THAP10 THAP domain containing 10
THOC6 THO complex 6
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TPRA1 transmembrane protein, adipocyte asscociated 1
TTC23 tetratricopeptide repeat domain 23
TUBA3C tubulin, alpha 3c
TUBG2 tubulin, gamma 2
UBXN6 UBX domain protein 6
UNC93B1 unc-93 homolog B1 (C. elegans)
ZHX2 zinc fingers and homeoboxes 2
ZNF280B zinc finger protein 280B
ZNF862 zinc finger protein 862