terconazole-4583 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the terconazole-4583 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AFF4 AF4/FMR2 family, member 4
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATAD2B ATPase family, AAA domain containing 2B
BCL2 B-cell CLL/lymphoma 2
C1QTNF3 C1q and tumor necrosis factor related protein 3
C8ORF44 chromosome 8 open reading frame 44
CA5B carbonic anhydrase VB, mitochondrial
CALML4 calmodulin-like 4
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CAMKMT calmodulin-lysine N-methyltransferase
CAV2 caveolin 2
CCDC186 coiled-coil domain containing 186
CCNG2 cyclin G2
CD24 CD24 molecule
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CLCN4 chloride channel, voltage-sensitive 4
CREM cAMP responsive element modulator
CROCCP3 ciliary rootlet coiled-coil, rootletin pseudogene 3
CRY2 cryptochrome circadian clock 2
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CWH43 cell wall biogenesis 43 C-terminal homolog (S. cerevisiae)
CYB5R2 cytochrome b5 reductase 2
DCTN1 dynactin 1
DNAAF1 dynein, axonemal, assembly factor 1
DOCK6 dedicator of cytokinesis 6
DTX3 deltex 3, E3 ubiquitin ligase
EGR2 early growth response 2
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
EMC1 ER membrane protein complex subunit 1
ENOX1 ecto-NOX disulfide-thiol exchanger 1
ESRRG estrogen-related receptor gamma
ETV1 ets variant 1
FRMD8 FERM domain containing 8
GLRB glycine receptor, beta
GPM6B glycoprotein M6B
GRM2 glutamate receptor, metabotropic 2
HEMK1 HemK methyltransferase family member 1
HIST1H3F histone cluster 1, H3f
HNF1B HNF1 homeobox B
HNMT histamine N-methyltransferase
IGHMBP2 immunoglobulin mu binding protein 2
IL1RAP interleukin 1 receptor accessory protein
ING4 inhibitor of growth family, member 4
INSIG1 insulin induced gene 1
KLF4 Kruppel-like factor 4 (gut)
LDLR low density lipoprotein receptor
LIMD1 LIM domains containing 1
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1
MBNL3 muscleblind-like splicing regulator 3
MET MET proto-oncogene, receptor tyrosine kinase
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MLX MLX, MAX dimerization protein
NEK9 NIMA-related kinase 9
NFIB nuclear factor I/B
NFRKB nuclear factor related to kappaB binding protein
NPR2 natriuretic peptide receptor 2
NSUN6 NOP2/Sun domain family, member 6
NTF3 neurotrophin 3
NUP160 nucleoporin 160kDa
NXPE3 neurexophilin and PC-esterase domain family, member 3
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PDE4D phosphodiesterase 4D, cAMP-specific
PHF20 PHD finger protein 20
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PKNOX2 PBX/knotted 1 homeobox 2
PLD1 phospholipase D1, phosphatidylcholine-specific
PLEKHS1 pleckstrin homology domain containing, family S member 1
PTCRA pre T-cell antigen receptor alpha
RAB6A RAB6A, member RAS oncogene family
RBMS2 RNA binding motif, single stranded interacting protein 2
REEP2 receptor accessory protein 2
RNGTT RNA guanylyltransferase and 5'-phosphatase
RPS28 ribosomal protein S28
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
SETD1A SET domain containing 1A
SH3BP2 SH3-domain binding protein 2
SLC30A5 solute carrier family 30 (zinc transporter), member 5
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5)
SNX13 sorting nexin 13
SOGA1 suppressor of glucose, autophagy associated 1
SPRED2 sprouty-related, EVH1 domain containing 2
SQLE squalene epoxidase
ST7L suppression of tumorigenicity 7 like
STS steroid sulfatase (microsomal), isozyme S
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
TAS2R1 taste receptor, type 2, member 1
TBC1D30 TBC1 domain family, member 30
TBX6 T-box 6
TRIO trio Rho guanine nucleotide exchange factor
TRPC1 transient receptor potential cation channel, subfamily C, member 1
TTLL1 tubulin tyrosine ligase-like family member 1
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast)
WSB1 WD repeat and SOCS box containing 1
ZNF227 zinc finger protein 227
ZNF268 zinc finger protein 268
ZNF286A zinc finger protein 286A
ZNF74 zinc finger protein 74

decreased expression

Symbol Name
AATK apoptosis-associated tyrosine kinase
ACVR2B activin A receptor, type IIB
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3
ADGRB2 adhesion G protein-coupled receptor B2
AGMAT agmatine ureohydrolase (agmatinase)
ARHGAP10 Rho GTPase activating protein 10
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
BMP15 bone morphogenetic protein 15
C11ORF80 chromosome 11 open reading frame 80
C1S complement component 1, s subcomponent
C22ORF46 chromosome 22 open reading frame 46
C7ORF43 chromosome 7 open reading frame 43
CAPN5 calpain 5
CDADC1 cytidine and dCMP deaminase domain containing 1
CDK6 cyclin-dependent kinase 6
CINP cyclin-dependent kinase 2 interacting protein
CLCA1 chloride channel accessory 1
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CNTNAP3B contactin associated protein-like 3B
CPNE7 copine VII
CREB5 cAMP responsive element binding protein 5
CXCL3 chemokine (C-X-C motif) ligand 3
DBF4B DBF4 zinc finger B
DCUN1D2 DCN1, defective in cullin neddylation 1, domain containing 2
DDN dendrin
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
ELAVL3 ELAV like neuron-specific RNA binding protein 3
EN2 engrailed homeobox 2
ERN2 endoplasmic reticulum to nucleus signaling 2
GAS8 growth arrest-specific 8
H2AFJ H2A histone family, member J
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIST1H1D histone cluster 1, H1d
HIST1H2BM histone cluster 1, H2bm
HIST1H3C histone cluster 1, H3c
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IFNA14 interferon, alpha 14
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IL17RB interleukin 17 receptor B
IREB2 iron-responsive element binding protein 2
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITPKB inositol-trisphosphate 3-kinase B
LIME1 Lck interacting transmembrane adaptor 1
LRP5L low density lipoprotein receptor-related protein 5-like
LTB4R leukotriene B4 receptor
LY6D lymphocyte antigen 6 complex, locus D
LYRM9 LYR motif containing 9
MAGEF1 melanoma antigen family F1
MEGF8 multiple EGF-like-domains 8
MFSD12 major facilitator superfamily domain containing 12
MGP matrix Gla protein
MITF microphthalmia-associated transcription factor
MLYCD malonyl-CoA decarboxylase
MYO1F myosin IF
NDP Norrie disease (pseudoglioma)
NOTCH1 notch 1
NPIPB3 nuclear pore complex interacting protein family, member B3
OASL 2'-5'-oligoadenylate synthetase-like
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PELP1 proline, glutamate and leucine rich protein 1
PICK1 protein interacting with PRKCA 1
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
POLH polymerase (DNA directed), eta
PPL periplakin
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PXMP4 peroxisomal membrane protein 4, 24kDa
RAB36 RAB36, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RPL23AP32 ribosomal protein L23a pseudogene 32
SCIN scinderin
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SLC46A3 solute carrier family 46, member 3
SNPH syntaphilin
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
SUGCT succinyl-CoA:glutarate-CoA transferase
SYCP2 synaptonemal complex protein 2
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TAOK1 TAO kinase 1
TCTN1 tectonic family member 1
TIAM2 T-cell lymphoma invasion and metastasis 2
TINAGL1 tubulointerstitial nephritis antigen-like 1
TSC22D4 TSC22 domain family, member 4
VGF VGF nerve growth factor inducible
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF197 zinc finger protein 197
ZNF222 zinc finger protein 222
ZNF334 zinc finger protein 334
ZNF343 zinc finger protein 343
ZNF702P zinc finger protein 702, pseudogene
ZNF747 zinc finger protein 747
ZNF813 zinc finger protein 813