telenzepine-2388 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the telenzepine-2388 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADCY2 adenylate cyclase 2 (brain)
AFF4 AF4/FMR2 family, member 4
ARTN artemin
ASIC4 acid sensing (proton gated) ion channel family member 4
ATXN2L ataxin 2-like
CAMK4 calcium/calmodulin-dependent protein kinase IV
CCDC28B coiled-coil domain containing 28B
CCL21 chemokine (C-C motif) ligand 21
CDHR2 cadherin-related family member 2
CDK13 cyclin-dependent kinase 13
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CLSTN2 calsyntenin 2
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CRYAB crystallin, alpha B
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DLX2 distal-less homeobox 2
DNPEP aspartyl aminopeptidase
EDNRA endothelin receptor type A
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2
EFNA3 ephrin-A3
EMC3 ER membrane protein complex subunit 3
EMX1 empty spiracles homeobox 1
FOXO1 forkhead box O1
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GLE1 GLE1 RNA export mediator
GLRX3 glutaredoxin 3
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GP2 glycoprotein 2 (zymogen granule membrane)
GVINP1 GTPase, very large interferon inducible pseudogene 1
H2AFX H2A histone family, member X
HCRTR1 hypocretin (orexin) receptor 1
HGD homogentisate 1,2-dioxygenase
HIST1H2AL histone cluster 1, H2al
HMHB1 histocompatibility (minor) HB-1
HNMT histamine N-methyltransferase
HRASLS2 HRAS-like suppressor 2
HYAL3 hyaluronoglucosaminidase 3
IBA57 IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
ICA1 islet cell autoantigen 1, 69kDa
IDI2-AS1 IDI2 antisense RNA 1
INPP5J inositol polyphosphate-5-phosphatase J
IQCE IQ motif containing E
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
JAG1 jagged 1
KDM4B lysine (K)-specific demethylase 4B
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
KIF13B kinesin family member 13B
KLK7 kallikrein-related peptidase 7
KMT2A lysine (K)-specific methyltransferase 2A
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LAD1 ladinin 1
LIMK2 LIM domain kinase 2
MAOA monoamine oxidase A
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MED25 mediator complex subunit 25
MICALL1 MICAL-like 1
MRPS18C mitochondrial ribosomal protein S18C
MYOF myoferlin
NDE1 nudE neurodevelopment protein 1
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
NOP16 NOP16 nucleolar protein
OASL 2'-5'-oligoadenylate synthetase-like
PEX16 peroxisomal biogenesis factor 16
PHC1 polyhomeotic homolog 1 (Drosophila)
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1
PLK4 polo-like kinase 4
PODNL1 podocan-like 1
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
PTGIR prostaglandin I2 (prostacyclin) receptor (IP)
RAB2A RAB2A, member RAS oncogene family
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RNF17 ring finger protein 17
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
RUNX1 runt-related transcription factor 1
SCARA3 scavenger receptor class A, member 3
SCLY selenocysteine lyase
SFRP5 secreted frizzled-related protein 5
SIGLEC9 sialic acid binding Ig-like lectin 9
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC35F6 solute carrier family 35, member F6
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SS18 synovial sarcoma translocation, chromosome 18
STAG3L4 stromal antigen 3-like 4 (pseudogene)
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TNS4 tensin 4
TRPC3 transient receptor potential cation channel, subfamily C, member 3
TSKU tsukushi, small leucine rich proteoglycan
TTC30A tetratricopeptide repeat domain 30A
TTC9 tetratricopeptide repeat domain 9
ZNF34 zinc finger protein 34
ZNF646 zinc finger protein 646
ZNF93 zinc finger protein 93

decreased expression

Symbol Name
ACPP acid phosphatase, prostate
AGO4 argonaute RISC catalytic component 4
AHDC1 AT hook, DNA binding motif, containing 1
ARHGAP10 Rho GTPase activating protein 10
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
AXIN1 axin 1
AZI2 5-azacytidine induced 2
B3GNT1
BAHD1 bromo adjacent homology domain containing 1
C19ORF40 chromosome 19 open reading frame 40
C5ORF28 chromosome 5 open reading frame 28
CAPN1 calpain 1, (mu/I) large subunit
CAPN15 calpain 15
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CD1D CD1d molecule
CDADC1 cytidine and dCMP deaminase domain containing 1
CDK6 cyclin-dependent kinase 6
CEP72 centrosomal protein 72kDa
CIDEC cell death-inducing DFFA-like effector c
CNN2 calponin 2
CORO7 coronin 7
CSF1R colony stimulating factor 1 receptor
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DCTN4 dynactin 4 (p62)
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DPY19L2P2 DPY19L2 pseudogene 2
ECM1 extracellular matrix protein 1
ELAC1 elaC ribonuclease Z 1
EML4 echinoderm microtubule associated protein like 4
ERAP2 endoplasmic reticulum aminopeptidase 2
ERCC5 excision repair cross-complementation group 5
ETAA1 Ewing tumor-associated antigen 1
F3 coagulation factor III (thromboplastin, tissue factor)
FAM118A family with sequence similarity 118, member A
FAM53B family with sequence similarity 53, member B
FAM63A family with sequence similarity 63, member A
FANCC Fanconi anemia, complementation group C
FHL3 four and a half LIM domains 3
FXN frataxin
GMEB1 glucocorticoid modulatory element binding protein 1
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GPATCH3 G patch domain containing 3
GPR22 G protein-coupled receptor 22
GPR27 G protein-coupled receptor 27
HAMP hepcidin antimicrobial peptide
HAUS6 HAUS augmin-like complex, subunit 6
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HOPX HOP homeobox
HYAL2 hyaluronoglucosaminidase 2
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
ITGB7 integrin, beta 7
KCTD20 potassium channel tetramerization domain containing 20
KCTD3 potassium channel tetramerization domain containing 3
KIAA1024 KIAA1024
KIF3B kinesin family member 3B
L2HGDH L-2-hydroxyglutarate dehydrogenase
LRP3 low density lipoprotein receptor-related protein 3
MANEA mannosidase, endo-alpha
MBIP MAP3K12 binding inhibitory protein 1
METRN meteorin, glial cell differentiation regulator
METTL2B methyltransferase like 2B
MTRF1 mitochondrial translational release factor 1
NFE2L3 nuclear factor, erythroid 2-like 3
NPFFR1 neuropeptide FF receptor 1
NPIPB3 nuclear pore complex interacting protein family, member B3
NTSR1 neurotensin receptor 1 (high affinity)
NUBPL nucleotide binding protein-like
OTUD3 OTU deubiquitinase 3
PGPEP1 pyroglutamyl-peptidase I
POLE polymerase (DNA directed), epsilon, catalytic subunit
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1
PTPN9 protein tyrosine phosphatase, non-receptor type 9
PYCRL pyrroline-5-carboxylate reductase-like
RAB3A RAB3A, member RAS oncogene family
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RPL23AP32 ribosomal protein L23a pseudogene 32
SAMD9 sterile alpha motif domain containing 9
SLC22A14 solute carrier family 22, member 14
SLC22A18 solute carrier family 22, member 18
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SPON2 spondin 2, extracellular matrix protein
STARD8 StAR-related lipid transfer (START) domain containing 8
STXBP1 syntaxin binding protein 1
TEC tec protein tyrosine kinase
THBS4 thrombospondin 4
THEM6 thioesterase superfamily member 6
TMEM57 transmembrane protein 57
TMOD3 tropomodulin 3 (ubiquitous)
TOM1 target of myb1 (chicken)
TRAPPC13 trafficking protein particle complex 13
TTBK2 tau tubulin kinase 2
TTC33 tetratricopeptide repeat domain 33
TUBGCP5 tubulin, gamma complex associated protein 5
USP27X ubiquitin specific peptidase 27, X-linked
ZBTB10 zinc finger and BTB domain containing 10
ZHX2 zinc fingers and homeoboxes 2
ZNF16 zinc finger protein 16
ZNF571 zinc finger protein 571
ZNF747 zinc finger protein 747
ZNF813 zinc finger protein 813