tamoxifen-6768 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the tamoxifen-6768 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
AKAP8L A kinase (PRKA) anchor protein 8-like
ALS2CL ALS2 C-terminal like
ANXA1 annexin A1
APOE apolipoprotein E
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ATF3 activating transcription factor 3
BBS9 Bardet-Biedl syndrome 9
BHLHE40 basic helix-loop-helix family, member e40
C17ORF59 chromosome 17 open reading frame 59
C1ORF54 chromosome 1 open reading frame 54
CA4 carbonic anhydrase IV
CDK14 cyclin-dependent kinase 14
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHKB choline kinase beta
CLCN7 chloride channel, voltage-sensitive 7
CLSTN3 calsyntenin 3
COL11A2 collagen, type XI, alpha 2
CSNK1G1 casein kinase 1, gamma 1
CXCR4 chemokine (C-X-C motif) receptor 4
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DSTYK dual serine/threonine and tyrosine protein kinase
DUSP10 dual specificity phosphatase 10
EFNA1 ephrin-A1
EGR1 early growth response 1
EHD2 EH-domain containing 2
FAM204A family with sequence similarity 204, member A
FGD1 FYVE, RhoGEF and PH domain containing 1
FILIP1L filamin A interacting protein 1-like
FOS FBJ murine osteosarcoma viral oncogene homolog
FSCN1 fascin actin-bundling protein 1
GADD45A growth arrest and DNA-damage-inducible, alpha
GRM1 glutamate receptor, metabotropic 1
HAP1 huntingtin-associated protein 1
HBEGF heparin-binding EGF-like growth factor
HCAR3 hydroxycarboxylic acid receptor 3
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIST1H2BJ histone cluster 1, H2bj
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
ING4 inhibitor of growth family, member 4
INHBE inhibin, beta E
IRAK3 interleukin-1 receptor-associated kinase 3
ISG20 interferon stimulated exonuclease gene 20kDa
ITM2C integral membrane protein 2C
JUN jun proto-oncogene
JUNB jun B proto-oncogene
KLF2 Kruppel-like factor 2
LRRC14 leucine rich repeat containing 14
LRRC37A3 leucine rich repeat containing 37, member A3
LTB lymphotoxin beta (TNF superfamily, member 3)
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MFAP3L microfibrillar-associated protein 3-like
MMP19 matrix metallopeptidase 19
MT1F metallothionein 1F
NBR2 neighbor of BRCA1 gene 2 (non-protein coding)
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NUPR1 nuclear protein, transcriptional regulator, 1
OASL 2'-5'-oligoadenylate synthetase-like
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PDCD6 programmed cell death 6
PHLDA1 pleckstrin homology-like domain, family A, member 1
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PLD1 phospholipase D1, phosphatidylcholine-specific
PLXND1 plexin D1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPARD peroxisome proliferator-activated receptor delta
PROL1 proline rich, lacrimal 1
PSG1 pregnancy specific beta-1-glycoprotein 1
RND1 Rho family GTPase 1
RNF19B ring finger protein 19B
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
TAOK2 TAO kinase 2
TBX6 T-box 6
TESPA1 thymocyte expressed, positive selection associated 1
TGM2 transglutaminase 2
TK2 thymidine kinase 2, mitochondrial
TLR2 toll-like receptor 2
TMPRSS2 transmembrane protease, serine 2
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TRAF3IP3 TRAF3 interacting protein 3
TYR tyrosinase
WDR19 WD repeat domain 19
WDR55 WD repeat domain 55
ZNF446 zinc finger protein 446
ZSWIM1 zinc finger, SWIM-type containing 1

decreased expression

Symbol Name
ACAD10 acyl-CoA dehydrogenase family, member 10
ADGRG2 adhesion G protein-coupled receptor G2
AKAP12 A kinase (PRKA) anchor protein 12
ANXA2P3 annexin A2 pseudogene 3
ARC activity-regulated cytoskeleton-associated protein
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
AXIN1 axin 1
C19ORF73 chromosome 19 open reading frame 73
CBX8 chromobox homolog 8
CCDC134 coiled-coil domain containing 134
CGA glycoprotein hormones, alpha polypeptide
CHST10 carbohydrate sulfotransferase 10
CORO7 coronin 7
CRYBB2P1 crystallin, beta B2 pseudogene 1
CTNNBIP1 catenin, beta interacting protein 1
CXCL12 chemokine (C-X-C motif) ligand 12
DLEU2 deleted in lymphocytic leukemia 2 (non-protein coding)
ERN2 endoplasmic reticulum to nucleus signaling 2
ETAA1 Ewing tumor-associated antigen 1
F2R coagulation factor II (thrombin) receptor
FAM184A family with sequence similarity 184, member A
FAM198B family with sequence similarity 198, member B
FAM86C1 family with sequence similarity 86, member C1
FBRS fibrosin
FOXC1 forkhead box C1
FRS2 fibroblast growth factor receptor substrate 2
GAMT guanidinoacetate N-methyltransferase
GATA4 GATA binding protein 4
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
HIRA histone cell cycle regulator
HIST1H1D histone cluster 1, H1d
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HOXC10 homeobox C10
HOXC8 homeobox C8
HPN hepsin
IDI2-AS1 IDI2 antisense RNA 1
IFI6 interferon, alpha-inducible protein 6
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KCNK15 potassium channel, two pore domain subfamily K, member 15
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LGALS4 lectin, galactoside-binding, soluble, 4
LIME1 Lck interacting transmembrane adaptor 1
LRP5L low density lipoprotein receptor-related protein 5-like
LRRC61 leucine rich repeat containing 61
MAGEF1 melanoma antigen family F1
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MAST3 microtubule associated serine/threonine kinase 3
MED9 mediator complex subunit 9
MRPL44 mitochondrial ribosomal protein L44
MYL5 myosin, light chain 5, regulatory
NPY1R neuropeptide Y receptor Y1
NUP62CL nucleoporin 62kDa C-terminal like
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
PADI1 peptidyl arginine deiminase, type I
PCDH12 protocadherin 12
PCOLCE2 procollagen C-endopeptidase enhancer 2
PDZK1 PDZ domain containing 1
PGBD5 piggyBac transposable element derived 5
PHC1 polyhomeotic homolog 1 (Drosophila)
PICK1 protein interacting with PRKCA 1
PPT2 palmitoyl-protein thioesterase 2
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RHBG Rh family, B glycoprotein (gene/pseudogene)
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RPGR retinitis pigmentosa GTPase regulator
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SDC3 syndecan 3
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLIT2 slit homolog 2 (Drosophila)
SMCO4 single-pass membrane protein with coiled-coil domains 4
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SPAG4 sperm associated antigen 4
SPAG7 sperm associated antigen 7
SPRR2B small proline-rich protein 2B
STAG3 stromal antigen 3
STIM1 stromal interaction molecule 1
STMN3 stathmin-like 3
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
SYMPK symplekin
TBX19 T-box 19
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor)
TMEM120B transmembrane protein 120B
TMEM180 transmembrane protein 180
TUBA3C tubulin, alpha 3c
USP19 ubiquitin specific peptidase 19
USP36 ubiquitin specific peptidase 36
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
YY2 YY2 transcription factor
ZNF442 zinc finger protein 442
ZNF480 zinc finger protein 480
ZNF586 zinc finger protein 586
ZNF623 zinc finger protein 623
ZNF770 zinc finger protein 770