talampicillin-7014 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the talampicillin-7014 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AFF2 AF4/FMR2 family, member 2
ANP32A-IT1 ANP32A intronic transcript 1
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
APLP2 amyloid beta (A4) precursor-like protein 2
APOD apolipoprotein D
C14ORF93 chromosome 14 open reading frame 93
C2ORF54 chromosome 2 open reading frame 54
C8ORF60 chromosome 8 open reading frame 60
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CBX8 chromobox homolog 8
CC2D1A coiled-coil and C2 domain containing 1A
CCDC186 coiled-coil domain containing 186
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CTAG2 cancer/testis antigen 2
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
DAPK3 death-associated protein kinase 3
DCHS1 dachsous cadherin-related 1
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DOHH deoxyhypusine hydroxylase/monooxygenase
DUSP6 dual specificity phosphatase 6
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4
EXOSC2 exosome component 2
F5 coagulation factor V (proaccelerin, labile factor)
FPR1 formyl peptide receptor 1
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GLS2 glutaminase 2 (liver, mitochondrial)
GPX2 glutathione peroxidase 2
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HMOX1 heme oxygenase 1
HOXA4 homeobox A4
HSPA12A heat shock 70kDa protein 12A
IFNA16 interferon, alpha 16
IGHMBP2 immunoglobulin mu binding protein 2
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KLK5 kallikrein-related peptidase 5
KRT24 keratin 24, type I
KRT83 keratin 83, type II
LMNA lamin A/C
LRRC23 leucine rich repeat containing 23
MBD3 methyl-CpG binding domain protein 3
MID1 midline 1
MLX MLX, MAX dimerization protein
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NEURL1 neuralized E3 ubiquitin protein ligase 1
NF1 neurofibromin 1
NF2 neurofibromin 2 (merlin)
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NOX5 NADPH oxidase, EF-hand calcium binding domain 5
PADI1 peptidyl arginine deiminase, type I
PCDHGA10 protocadherin gamma subfamily A, 10
PCNX pecanex homolog (Drosophila)
PDCD6 programmed cell death 6
PLAUR plasminogen activator, urokinase receptor
POM121L2 POM121 transmembrane nucleoporin-like 2
POMT2 protein-O-mannosyltransferase 2
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PRODH proline dehydrogenase (oxidase) 1
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPRA protein tyrosine phosphatase, receptor type, A
PTRF polymerase I and transcript release factor
RAB36 RAB36, member RAS oncogene family
RANGAP1 Ran GTPase activating protein 1
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RER1 retention in endoplasmic reticulum sorting receptor 1
RGS12 regulator of G-protein signaling 12
RNF122 ring finger protein 122
RNF19B ring finger protein 19B
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
RSU1 Ras suppressor protein 1
S100A7 S100 calcium binding protein A7
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SAP30 Sin3A-associated protein, 30kDa
SASH1 SAM and SH3 domain containing 1
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SGSH N-sulfoglucosamine sulfohydrolase
SH2B3 SH2B adaptor protein 3
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
ST7 suppression of tumorigenicity 7
TBX5 T-box 5
TFR2 transferrin receptor 2
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TLR5 toll-like receptor 5
TMEM63A transmembrane protein 63A
TOM1 target of myb1 (chicken)
TREX1 three prime repair exonuclease 1
UNC119 unc-119 homolog (C. elegans)
VDAC3 voltage-dependent anion channel 3
VLDLR very low density lipoprotein receptor
ZNF771 zinc finger protein 771

decreased expression

Symbol Name
ABHD14A abhydrolase domain containing 14A
ADAM15 ADAM metallopeptidase domain 15
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ATAD5 ATPase family, AAA domain containing 5
ATG2B autophagy related 2B
ATP13A2 ATPase type 13A2
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BBS10 Bardet-Biedl syndrome 10
C1ORF106 chromosome 1 open reading frame 106
C1ORF109 chromosome 1 open reading frame 109
C1ORF115 chromosome 1 open reading frame 115
C1ORF56 chromosome 1 open reading frame 56
C21ORF91 chromosome 21 open reading frame 91
C3ORF52 chromosome 3 open reading frame 52
CDR2L cerebellar degeneration-related protein 2-like
CEP170B centrosomal protein 170B
CEP85 centrosomal protein 85kDa
CLDND1 claudin domain containing 1
CPTP ceramide-1-phosphate transfer protein
CXORF56 chromosome X open reading frame 56
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DHRS11 dehydrogenase/reductase (SDR family) member 11
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
ECSIT ECSIT signalling integrator
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
EMD emerin
ETAA1 Ewing tumor-associated antigen 1
EYA2 EYA transcriptional coactivator and phosphatase 2
FASTKD5 FAST kinase domains 5
FBXO3 F-box protein 3
FRAT1 frequently rearranged in advanced T-cell lymphomas 1
FSD1 fibronectin type III and SPRY domain containing 1
FZD3 frizzled class receptor 3
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GLCE glucuronic acid epimerase
GPKOW G patch domain and KOW motifs
GPR19 G protein-coupled receptor 19
HIST1H2AJ histone cluster 1, H2aj
HSPA2 heat shock 70kDa protein 2
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
KIF16B kinesin family member 16B
KRI1 KRI1 homolog (S. cerevisiae)
KRT8P12 keratin 8 pseudogene 12
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LRRC61 leucine rich repeat containing 61
MAP3K11 mitogen-activated protein kinase kinase kinase 11
MAPKBP1 mitogen-activated protein kinase binding protein 1
MEIS1 Meis homeobox 1
MNS1 meiosis-specific nuclear structural 1
MSANTD2 Myb/SANT-like DNA-binding domain containing 2
MT1HL1 metallothionein 1H-like 1
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit
NECAP2 NECAP endocytosis associated 2
NES nestin
PADI2 peptidyl arginine deiminase, type II
PANX1 pannexin 1
PARD6A par-6 family cell polarity regulator alpha
PBX3 pre-B-cell leukemia homeobox 3
PEX10 peroxisomal biogenesis factor 10
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
RAB8B RAB8B, member RAS oncogene family
RAD54L RAD54-like (S. cerevisiae)
RAD9A RAD9 homolog A (S. pombe)
RBL1 retinoblastoma-like 1
RECQL4 RecQ protein-like 4
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit
RIPK4 receptor-interacting serine-threonine kinase 4
RNF216 ring finger protein 216
RPL13P5 ribosomal protein L13 pseudogene 5
RWDD3 RWD domain containing 3
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SLC16A6 solute carrier family 16, member 6
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC46A3 solute carrier family 46, member 3
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)
SP140L SP140 nuclear body protein-like
STK25 serine/threonine kinase 25
TBC1D10B TBC1 domain family, member 10B
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TM7SF3 transmembrane 7 superfamily member 3
TMEM2 transmembrane protein 2
TROAP trophinin associated protein
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TXLNG taxilin gamma
USP36 ubiquitin specific peptidase 36
VWA1 von Willebrand factor A domain containing 1
WDR18 WD repeat domain 18
XYLT2 xylosyltransferase II
YBX2 Y box binding protein 2
YEATS4 YEATS domain containing 4
ZMYM1 zinc finger, MYM-type 1
ZNF12 zinc finger protein 12
ZNF232 zinc finger protein 232
ZNF254 zinc finger protein 254
ZNF552 zinc finger protein 552
ZNF768 zinc finger protein 768
ZNF8 zinc finger protein 8
ZNF83 zinc finger protein 83