t-lymphocyte Gene Set

Dataset TISSUES Curated Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description Any of several lymphocytes (as a helper T cell) that differentiate in the thymus, possess highly specific cell-surface antigen receptors, and include some that control the initiation or suppression of cell-mediated and humoral immunity (as by the regulation of T and B cell maturation and proliferation) and others that lyse antigen-bearing cells. (BRENDA Tissue and Enzyme Source Ontology, BTO_0000782)
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Genes

291 proteins highly expressed in the tissue t-lymphocyte from the TISSUES Curated Tissue Protein Expression Evidence Scores dataset.

Symbol Name
AAK1 AP2 associated kinase 1
ABI1 abl-interactor 1
ACIN1 apoptotic chromatin condensation inducer 1
ACTR3 ARP3 actin-related protein 3 homolog (yeast)
AHNAK AHNAK nucleoprotein
AP1M1 adaptor-related protein complex 1, mu 1 subunit
APAF1 apoptotic peptidase activating factor 1
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ATR ATR serine/threonine kinase
BAG1 BCL2-associated athanogene
BAG6 BCL2-associated athanogene 6
BCL2A1 BCL2-related protein A1
BCLAF1 BCL2-associated transcription factor 1
BIN1 bridging integrator 1
BIN2 bridging integrator 2
BMF Bcl2 modifying factor
BRD2 bromodomain containing 2
BRD7 bromodomain containing 7
BRD8 bromodomain containing 8
C10ORF54 chromosome 10 open reading frame 54
C14ORF159 chromosome 14 open reading frame 159
C17ORF70 chromosome 17 open reading frame 70
C6ORF25 chromosome 6 open reading frame 25
C9ORF78 chromosome 9 open reading frame 78
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast)
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1
CASP10 caspase 10, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP6 caspase 6, apoptosis-related cysteine peptidase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP8AP2 caspase 8 associated protein 2
CASP9 caspase 9, apoptosis-related cysteine peptidase
CCDC86 coiled-coil domain containing 86
CCL3 chemokine (C-C motif) ligand 3
CCL3L1 chemokine (C-C motif) ligand 3-like 1
CCL4 chemokine (C-C motif) ligand 4
CCL4L1 chemokine (C-C motif) ligand 4-like 1
CCNG2 cyclin G2
CCNK cyclin K
CCNO cyclin O
CCNY cyclin Y
CD1A CD1a molecule
CD28 CD28 molecule
CD2BP2 CD2 (cytoplasmic tail) binding protein 2
CD44 CD44 molecule (Indian blood group)
CD47 CD47 molecule
CD59 CD59 molecule, complement regulatory protein
CD8B CD8b molecule
CD99 CD99 molecule
CD99L2 CD99 molecule-like 2
CDX2 caudal type homeobox 2
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma
CFLAR CASP8 and FADD-like apoptosis regulator
CHD2 chromodomain helicase DNA binding protein 2
CHEK2 checkpoint kinase 2
CHKB choline kinase beta
CHUK conserved helix-loop-helix ubiquitous kinase
CLASP2 cytoplasmic linker associated protein 2
CMC4 C-x(9)-C motif containing 4
COG4 component of oligomeric golgi complex 4
CORO1A coronin, actin binding protein, 1A
CRACR2B calcium release activated channel regulator 2B
CRLF2 cytokine receptor-like factor 2
CTR9 CTR9, Paf1/RNA polymerase II complex component
DAXX death-domain associated protein
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DMTN dematin actin binding protein
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17
DOCK2 dedicator of cytokinesis 2
DOK4 docking protein 4
DRP2 dystrophin related protein 2
DUT deoxyuridine triphosphatase
EDC4 enhancer of mRNA decapping 4
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
EGR3 early growth response 3
EIF4A3 eukaryotic translation initiation factor 4A3
EIF5B eukaryotic translation initiation factor 5B
ENAH enabled homolog (Drosophila)
ENO1 enolase 1, (alpha)
EPN1 epsin 1
EVL Enah/Vasp-like
EXOSC10 exosome component 10
FAF2 Fas associated factor family member 2
FAM65B family with sequence similarity 65, member B
FGFBP2 fibroblast growth factor binding protein 2
FKBP4 FK506 binding protein 4, 59kDa
FLNA filamin A, alpha
FMNL1 formin-like 1
FN1 fibronectin 1
FNBP1 formin binding protein 1
FYN FYN proto-oncogene, Src family tyrosine kinase
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GATA3 GATA binding protein 3
GMPR2 guanosine monophosphate reductase 2
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
GNL1 guanine nucleotide binding protein-like 1
GP1BB glycoprotein Ib (platelet), beta polypeptide
GPSM1 G-protein signaling modulator 1
GRB2 growth factor receptor-bound protein 2
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
HAUS4 HAUS augmin-like complex, subunit 4
HDAC1 histone deacetylase 1
HDAC3 histone deacetylase 3
HDGF hepatoma-derived growth factor
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIRIP3 HIRA interacting protein 3
HMGA1 high mobility group AT-hook 1
HMGN1 high mobility group nucleosome binding domain 1
HMHA1 histocompatibility (minor) HA-1
HN1 hematological and neurological expressed 1
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2)
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HP1BP3 heterochromatin protein 1, binding protein 3
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HUS1 HUS1 checkpoint homolog (S. pombe)
IFI16 interferon, gamma-inducible protein 16
IGF2R insulin-like growth factor 2 receptor
IL10 interleukin 10
IL12RB2 interleukin 12 receptor, beta 2
IL13RA1 interleukin 13 receptor, alpha 1
IL17A interleukin 17A
IL17RA interleukin 17 receptor A
IL18BP interleukin 18 binding protein
IL1R1 interleukin 1 receptor, type I
IL23R interleukin 23 receptor
ILF3 interleukin enhancer binding factor 3, 90kDa
IPO5 importin 5
IRF2 interferon regulatory factor 2
ITGB7 integrin, beta 7
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
IWS1 IWS1 homolog (S. cerevisiae)
KBTBD8 kelch repeat and BTB (POZ) domain containing 8
KDM2A lysine (K)-specific demethylase 2A
KIAA0391 KIAA0391
KIF2C kinesin family member 2C
LARP4B La ribonucleoprotein domain family, member 4B
LAT2 linker for activation of T cells family, member 2
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LDHB lactate dehydrogenase B
LMNB2 lamin B2
LPAR3 lysophosphatidic acid receptor 3
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3
LRRFIP2 leucine rich repeat (in FLII) interacting protein 2
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae)
LSP1 lymphocyte-specific protein 1
LTB lymphotoxin beta (TNF superfamily, member 3)
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K6 mitogen-activated protein kinase kinase 6
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5
MATR3 matrin 3
MCM2 minichromosome maintenance complex component 2
MDH1 malate dehydrogenase 1, NAD (soluble)
MECP2 methyl CpG binding protein 2
MKNK1 MAP kinase interacting serine/threonine kinase 1
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MTCP1 mature T-cell proliferation 1
MYH9 myosin, heavy chain 9, non-muscle
MYO1F myosin IF
MYO9B myosin IXB
N4BP2 NEDD4 binding protein 2
NDFIP2 Nedd4 family interacting protein 2
NEK2 NIMA-related kinase 2
NELFE negative elongation factor complex member E
NFAM1 NFAT activating protein with ITAM motif 1
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
NFIL3 nuclear factor, interleukin 3 regulated
NFKBID nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta
NLK nemo-like kinase
NLRP1 NLR family, pyrin domain containing 1
NOTCH2 notch 2
NSFL1C NSFL1 (p97) cofactor (p47)
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1
NUMA1 nuclear mitotic apparatus protein 1
OSM oncostatin M
OXA1L oxidase (cytochrome c) assembly 1-like
PCSK5 proprotein convertase subtilisin/kexin type 5
PDS5B PDS5 cohesin associated factor B
PGRMC1 progesterone receptor membrane component 1
PLCG1 phospholipase C, gamma 1
PLEC plectin
PLEK pleckstrin
PLXDC2 plexin domain containing 2
PNN pinin, desmosome associated protein
POLE polymerase (DNA directed), epsilon, catalytic subunit
PPIG peptidylprolyl isomerase G (cyclophilin G)
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PPP1R8 protein phosphatase 1, regulatory subunit 8
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRRC2A proline-rich coiled-coil 2A
PSIP1 PC4 and SFRS1 interacting protein 1
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3
PTGES3 prostaglandin E synthase 3 (cytosolic)
PTK2 protein tyrosine kinase 2
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PTPRC protein tyrosine phosphatase, receptor type, C
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RBM14 RNA binding motif protein 14
RBM17 RNA binding motif protein 17
RBM25 RNA binding motif protein 25
RBM4 RNA binding motif protein 4
RCSD1 RCSD domain containing 1
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
REV1 REV1, polymerase (DNA directed)
RPL4 ribosomal protein L4
RPRD2 regulation of nuclear pre-mRNA domain containing 2
RPS11 ribosomal protein S11
RPS21 ribosomal protein S21
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
RSL1D1 ribosomal L1 domain containing 1
RYR3 ryanodine receptor 3
S100A9 S100 calcium binding protein A9
SAFB2 scaffold attachment factor B2
SAMHD1 SAM domain and HD domain 1
SDPR serum deprivation response
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SF1 splicing factor 1
SF3A1 splicing factor 3a, subunit 1, 120kDa
SH2D2A SH2 domain containing 2A
SH3BP1 SH3-domain binding protein 1
SH3KBP1 SH3-domain kinase binding protein 1
SIRPG signal-regulatory protein gamma
SLAMF1 signaling lymphocytic activation molecule family member 1
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SMAD6 SMAD family member 6
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
SMC3 structural maintenance of chromosomes 3
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5)
SNRNP27 small nuclear ribonucleoprotein 27kDa (U4/U6.U5)
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SORT1 sortilin 1
SP110 SP110 nuclear body protein
SP3 Sp3 transcription factor
SPN sialophorin
SRRM1 serine/arginine repetitive matrix 1
SRSF9 serine/arginine-rich splicing factor 9
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
STIM1 stromal interaction molecule 1
STK10 serine/threonine kinase 10
STK19 serine/threonine kinase 19
STRIP1 striatin interacting protein 1
TCEA1 transcription elongation factor A (SII), 1
TCF4 transcription factor 4
TCF7 transcription factor 7 (T-cell specific, HMG-box)
TESPA1 thymocyte expressed, positive selection associated 1
THNSL2 threonine synthase-like 2 (S. cerevisiae)
THRAP3 thyroid hormone receptor associated protein 3
THUMPD1 THUMP domain containing 1
TLX1 T-cell leukemia homeobox 1
TM9SF1 transmembrane 9 superfamily member 1
TMEM40 transmembrane protein 40
TMEM55B transmembrane protein 55B
TMPO thymopoietin
TNFRSF18 tumor necrosis factor receptor superfamily, member 18
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TOP2B topoisomerase (DNA) II beta 180kDa
TPD52L2 tumor protein D52-like 2
TPI1 triosephosphate isomerase 1
TRAF2 TNF receptor-associated factor 2
TRAF3 TNF receptor-associated factor 3
TRAIP TRAF interacting protein
TRIM21 tripartite motif containing 21
TRIM28 tripartite motif containing 28
TSC22D3 TSC22 domain family, member 3
TYR tyrosinase
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
USP4 ubiquitin specific peptidase 4 (proto-oncogene)
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast)
VCPKMT valosin containing protein lysine (K) methyltransferase
VIM vimentin
VIPR2 vasoactive intestinal peptide receptor 2
WAS Wiskott-Aldrich syndrome
WIPF1 WAS/WASL interacting protein family, member 1
YIF1A Yip1 interacting factor homolog A (S. cerevisiae)
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
ZBP1 Z-DNA binding protein 1
ZC3H18 zinc finger CCCH-type containing 18
ZFYVE19 zinc finger, FYVE domain containing 19
ZNF43 zinc finger protein 43