t-cell large granular lymphocyte leukemia Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A chronic lymphocytic leukemia that exhibits an unexplained, chronic (> 6 months) elevation in large granular lymphocytes (LGLs) in the peripheral blood. (Human Disease Ontology, DOID_0050751)
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Genes

55 genes co-occuring with the disease t-cell large granular lymphocyte leukemia in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
B3GAT1 beta-1,3-glucuronyltransferase 1 1.48779
PKHD1L1 polycystic kidney and hepatic disease 1 (autosomal recessive)-like 1 1.39652
NCAM1 neural cell adhesion molecule 1 1.311
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.26909
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma 0.985585
RIN3 Ras and Rab interactor 3 0.97254
SBF1 SET binding factor 1 0.944938
FOXN3 forkhead box N3 0.893359
CD5 CD5 molecule 0.861818
CD52 CD52 molecule 0.858952
CD4 CD4 molecule 0.795411
STAT5B signal transducer and activator of transcription 5B 0.789262
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.753306
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1) 0.694301
FASLG Fas ligand (TNF superfamily, member 6) 0.679499
CD7 CD7 molecule 0.66596
PIAS3 protein inhibitor of activated STAT, 3 0.623359
LCK LCK proto-oncogene, Src family tyrosine kinase 0.58433
MCL1 myeloid cell leukemia 1 0.572662
TIA1 TIA1 cytotoxic granule-associated RNA binding protein 0.561781
PRF1 perforin 1 (pore forming protein) 0.521888
TARP TCR gamma alternate reading frame protein 0.504973
SH2B3 SH2B adaptor protein 3 0.502675
CTF1 cardiotrophin 1 0.501909
ELL2 elongation factor, RNA polymerase II, 2 0.492359
FGR FGR proto-oncogene, Src family tyrosine kinase 0.480945
NCR1 natural cytotoxicity triggering receptor 1 0.463149
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.457864
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.407172
IFNGR1 interferon gamma receptor 1 0.381852
CD58 CD58 molecule 0.372217
ZEB2 zinc finger E-box binding homeobox 2 0.353027
TAL1 T-cell acute lymphocytic leukemia 1 0.350452
PTPRT protein tyrosine phosphatase, receptor type, T 0.34384
OSM oncostatin M 0.334681
HAVCR1 hepatitis A virus cellular receptor 1 0.33066
JAK2 Janus kinase 2 0.325916
CXCL2 chemokine (C-X-C motif) ligand 2 0.296211
C1QBP complement component 1, q subcomponent binding protein 0.294413
CXCR1 chemokine (C-X-C motif) receptor 1 0.263722
SLC5A8 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8 0.24715
CCR6 chemokine (C-C motif) receptor 6 0.245396
MICA MHC class I polypeptide-related sequence A 0.243295
GZMK granzyme K (granzyme 3; tryptase II) 0.238054
IL2 interleukin 2 0.216332
KLRD1 killer cell lectin-like receptor subfamily D, member 1 0.210253
KLRK1 killer cell lectin-like receptor subfamily K, member 1 0.208245
PAX5 paired box 5 0.205585
TRIM37 tripartite motif containing 37 0.189551
JAK1 Janus kinase 1 0.178126
TRAC T cell receptor alpha constant 0.165874
ERBB4 erb-b2 receptor tyrosine kinase 4 0.162505
NGF nerve growth factor (beta polypeptide) 0.161139
CXCR2 chemokine (C-X-C motif) receptor 2 0.160948
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.158951