t cell deficiency Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
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Genes

251 genes co-occuring with the disease t cell deficiency in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
TBX1 T-box 1 2.88221
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 1.89314
HIRA histone cell cycle regulator 1.84909
GSC2 goosecoid homeobox 2 1.81826
DGCR6 DiGeorge syndrome critical region gene 6 1.75323
CD4 CD4 molecule 1.71226
ZNF74 zinc finger protein 74 1.69496
PNP purine nucleoside phosphorylase 1.572
DGCR2 DiGeorge syndrome critical region gene 2 1.56844
UFD1L ubiquitin fusion degradation 1 like (yeast) 1.56089
DGCR14 DiGeorge syndrome critical region gene 14 1.49921
HIRIP3 HIRA interacting protein 3 1.45265
DGCR8 DGCR8 microprocessor complex subunit 1.38909
DGCR6L DiGeorge syndrome critical region gene 6-like 1.38166
ZBTB1 zinc finger and BTB domain containing 1 1.2992
CDC45 cell division cycle 45 1.25471
FOXN1 forkhead box N1 1.22822
NKX2-6 NK2 homeobox 6 1.22779
MRPL40 mitochondrial ribosomal protein L40 1.17636
PRODH proline dehydrogenase (oxidase) 1 1.16692
CHD7 chromodomain helicase DNA binding protein 7 1.13163
ZNF222 zinc finger protein 222 1.12572
PTER phosphotriesterase related 1.11477
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like 1.10258
DROSHA drosha, ribonuclease type III 1.07362
KLRAP1 killer cell lectin-like receptor subfamily A pseudogene 1 1.01174
POM121L7 POM121 transmembrane nucleoporin-like 7 0.997392
PMM2 phosphomannomutase 2 0.991487
HNRNPLL heterogeneous nuclear ribonucleoprotein L-like 0.991487
TRBV19 T cell receptor beta variable 19 0.960797
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 0.951187
IL2 interleukin 2 0.920498
CD3G CD3g molecule, gamma (CD3-TCR complex) 0.906086
RANBP1 RAN binding protein 1 0.898693
CECR2 cat eye syndrome chromosome region, candidate 2 0.897872
TBX10 T-box 10 0.8741
ORC2 origin recognition complex, subunit 2 0.872462
TBX5 T-box 5 0.86714
FGF8 fibroblast growth factor 8 (androgen-induced) 0.821257
IGSF3 immunoglobulin superfamily, member 3 0.815104
OTOG otogelin 0.80977
TMPO thymopoietin 0.80977
CD3E CD3e molecule, epsilon (CD3-TCR complex) 0.794591
CD79A CD79a molecule, immunoglobulin-associated alpha 0.790902
TCHP trichoplein, keratin filament binding 0.788442
DGUOK deoxyguanosine kinase 0.788442
IGKV1D-42 immunoglobulin kappa variable 1D-42 (non-functional) 0.783116
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1 0.781888
SLBP stem-loop binding protein 0.77575
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like 0.773705
USP18 ubiquitin specific peptidase 18 0.77207
EYA1 EYA transcriptional coactivator and phosphatase 1 0.763494
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 0.753306
CHRD chordin 0.752085
IL2RG interleukin 2 receptor, gamma 0.750864
GTF3A general transcription factor IIIA 0.74883
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C 0.748017
ANKLE2 ankyrin repeat and LEM domain containing 2 0.737865
TBX3 T-box 3 0.735027
IL7R interleukin 7 receptor 0.734217
C11ORF58 chromosome 11 open reading frame 58 0.721673
HIC2 hypermethylated in cancer 2 0.715215
GBX2 gastrulation brain homeobox 2 0.713198
CYP26C1 cytochrome P450, family 26, subfamily C, polypeptide 1 0.711587
SEPT5 septin 5 0.704742
TMC8 transmembrane channel-like 8 0.686291
CD40LG CD40 ligand 0.669538
CHAF1A chromatin assembly factor 1, subunit A (p150) 0.665166
RAP1GAP RAP1 GTPase activating protein 0.6608
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2 0.6608
TBX19 T-box 19 0.659215
SIX1 SIX homeobox 1 0.624927
FGF10 fibroblast growth factor 10 0.620617
MESP1 mesoderm posterior basic helix-loop-helix transcription factor 1 0.619051
ITPKB inositol-trisphosphate 3-kinase B 0.616703
SRSF4 serine/arginine-rich splicing factor 4 0.606543
MKRN3 makorin ring finger protein 3 0.590948
MED15 mediator complex subunit 15 0.590948
TMC6 transmembrane channel-like 6 0.587833
RAG1 recombination activating gene 1 0.587833
NEBL nebulette 0.572662
MUC17 mucin 17, cell surface associated 0.562169
BMPER BMP binding endothelial regulator 0.559062
NFU1 NFU1 iron-sulfur cluster scaffold 0.550134
HOXA3 homeobox A3 0.547807
STAU1 staufen double-stranded RNA binding protein 1 0.545868
LRRC32 leucine rich repeat containing 32 0.526904
THY1 Thy-1 cell surface antigen 0.505739
IRX1 iroquois homeobox 1 0.501527
SLC15A4 solute carrier family 15 (oligopeptide transporter), member 4 0.499997
YARS tyrosyl-tRNA synthetase 0.493122
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome 0.487027
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae) 0.485885
CD44 CD44 molecule (Indian blood group) 0.484364
PRF1 perforin 1 (pore forming protein) 0.482844
ATP10A ATPase, class V, type 10A 0.481705
TEF thyrotrophic embryonic factor 0.480186
BMP4 bone morphogenetic protein 4 0.479427
TGOLN2 trans-golgi network protein 2 0.455601
IRX2 iroquois homeobox 2 0.454847
SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit 0.454093
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) 0.453339
MNX1 motor neuron and pancreas homeobox 1 0.452962
PTH parathyroid hormone 0.451454
DEFB1 defensin, beta 1 0.450701
MUC13 mucin 13, cell surface associated 0.449571
MYH3 myosin, heavy chain 3, skeletal muscle, embryonic 0.446182
CELF2 CUGBP, Elav-like family member 2 0.443923
IL7 interleukin 7 0.442042
CLEC7A C-type lectin domain family 7, member A 0.439034
IRX3 iroquois homeobox 3 0.429642
SRSF2 serine/arginine-rich splicing factor 2 0.429266
NODAL nodal growth differentiation factor 0.429266
CD5 CD5 molecule 0.424014
OTX1 orthodenticle homeobox 1 0.42214
CD27 CD27 molecule 0.420641
DICER1 dicer 1, ribonuclease type III 0.420266
LAMC1 laminin, gamma 1 (formerly LAMB2) 0.412779
GSTT2 glutathione S-transferase theta 2 (gene/pseudogene) 0.408666
HOXB1 homeobox B1 0.407545
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 0.407172
TBX22 T-box 22 0.405305
FGF7 fibroblast growth factor 7 0.400453
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) 0.398216
GSTT2B glutathione S-transferase theta 2B (gene/pseudogene) 0.397471
CD247 CD247 molecule 0.39598
JAK3 Janus kinase 3 0.394863
B3GAT1 beta-1,3-glucuronyltransferase 1 0.392629
FOXG1 forkhead box G1 0.386679
SH2D1A SH2 domain containing 1A 0.385565
TARBP2 TAR (HIV-1) RNA binding protein 2 0.377031
FOXA2 forkhead box A2 0.374438
KAT6A K(lysine) acetyltransferase 6A 0.372587
LCK LCK proto-oncogene, Src family tyrosine kinase 0.371477
AMELY amelogenin, Y-linked 0.368149
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta 0.364824
CD38 CD38 molecule 0.360395
KLHL2 kelch-like family member 2 0.355235
TCF21 transcription factor 21 0.355235
STAT5B signal transducer and activator of transcription 5B 0.34384
HPRT1 hypoxanthine phosphoribosyltransferase 1 0.342739
AGO1 argonaute RISC catalytic component 1 0.342739
COMT catechol-O-methyltransferase 0.341639
TSPAN7 tetraspanin 7 0.339806
ADA adenosine deaminase 0.337608
AMELX amelogenin, X-linked 0.337608
TGFB1 transforming growth factor, beta 1 0.335412
CD69 CD69 molecule 0.335412
STAT5A signal transducer and activator of transcription 5A 0.334315
SRF serum response factor (c-fos serum response element-binding transcription factor) 0.332852
ASMT acetylserotonin O-methyltransferase 0.32701
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) 0.322637
MALT1 MALT1 paracaspase 0.321909
TRAC T cell receptor alpha constant 0.318272
E2F6 E2F transcription factor 6 0.309928
PHF12 PHD finger protein 12 0.307033
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.305226
SHH sonic hedgehog 0.303781
CD3D CD3d molecule, delta (CD3-TCR complex) 0.301976
DNAH9 dynein, axonemal, heavy chain 9 0.292616
GATA3 GATA binding protein 3 0.291539
GCM2 glial cells missing homolog 2 (Drosophila) 0.285802
OXA1L oxidase (cytochrome c) assembly 1-like 0.28294
BTK Bruton agammaglobulinemia tyrosine kinase 0.282582
CORO1A coronin, actin binding protein, 1A 0.27794
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.270464
POU3F4 POU class 3 homeobox 4 0.266913
NRP1 neuropilin 1 0.263014
BCR breakpoint cluster region 0.256299
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.253831
HECA headcase homolog (Drosophila) 0.25207
AIRE autoimmune regulator 0.25207
TBX2 T-box 2 0.249608
HLA-B major histocompatibility complex, class I, B 0.242245
C3 complement component 3 0.237706
ERCC3 excision repair cross-complementation group 3 0.235268
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.23353
BCAR1 breast cancer anti-estrogen resistance 1 0.231448
IL10RA interleukin 10 receptor, alpha 0.213959
IRF2 interferon regulatory factor 2 0.213959
CARD9 caspase recruitment domain family, member 9 0.211934
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 0.210253
IRF8 interferon regulatory factor 8 0.210253
WNT11 wingless-type MMTV integration site family, member 11 0.207578
DCLRE1C DNA cross-link repair 1C 0.202618
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 0.201308
RAG2 recombination activating gene 2 0.199033
VPREB1 pre-B lymphocyte 1 0.198064
BACE1 beta-site APP-cleaving enzyme 1 0.194232
OSTC oligosaccharyltransferase complex subunit (non-catalytic) 0.18591
CD8A CD8a molecule 0.182957
PRDM1 PR domain containing 1, with ZNF domain 0.180084
TIA1 TIA1 cytotoxic granule-associated RNA binding protein 0.177301
FYN FYN proto-oncogene, Src family tyrosine kinase 0.174354
CD7 CD7 molecule 0.174354
CD40 CD40 molecule, TNF receptor superfamily member 5 0.172291
PAX9 paired box 9 0.170789
HIST3H2BB histone cluster 3, H2bb 0.170544
HIST2H2BF histone cluster 2, H2bf 0.169571
HIST1H2BA histone cluster 1, H2ba 0.167915
HIST1H2BH histone cluster 1, H2bh 0.167682
HIST1H2BD histone cluster 1, H2bd 0.167682
TMSB4X thymosin beta 4, X-linked 0.166995
NKX2-5 NK2 homeobox 5 0.165435
PDZK1IP1 PDZK1 interacting protein 1 0.163317
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 0.161912
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.161716
TRADD TNFRSF1A-associated via death domain 0.161139
HEY2 hes-related family bHLH transcription factor with YRPW motif 2 0.160574
HIST1H2BC histone cluster 1, H2bc 0.159838
HIST1H2BF histone cluster 1, H2bf 0.159838
GZMM granzyme M (lymphocyte met-ase 1) 0.140458
STIM1 stromal interaction molecule 1 0.14026
MAGT1 magnesium transporter 1 0.139847
AHCY adenosylhomocysteinase 0.139663
ITGB4 integrin, beta 4 0.138797
CD2 CD2 molecule 0.138697
CD70 CD70 molecule 0.138688
ADK adenosine kinase 0.138289
PDCD1 programmed cell death 1 0.137563
APRT adenine phosphoribosyltransferase 0.137375
AFF2 AF4/FMR2 family, member 2 0.136429
TCL1A T-cell leukemia/lymphoma 1A 0.135423
DVL1 dishevelled segment polarity protein 1 0.134682
CUL1 cullin 1 0.134538
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 0.134457
FZD4 frizzled class receptor 4 0.134408
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 0.134359
DCK deoxycytidine kinase 0.134277
IL12RB1 interleukin 12 receptor, beta 1 0.134025
GFI1 growth factor independent 1 transcription repressor 0.133659
MYF5 myogenic factor 5 0.133298
HTN3 histatin 3 0.133055
NDN necdin, melanoma antigen (MAGE) family member 0.132959
POLG polymerase (DNA directed), gamma 0.132549
FOXC2 forkhead box C2 0.132306
APAF1 apoptotic peptidase activating factor 1 0.131932
ZKSCAN7 zinc finger with KRAB and SCAN domains 7 0.131205
GGT2 gamma-glutamyltransferase 2 0.131137
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.130475
CTSG cathepsin G 0.130451
IL2RA interleukin 2 receptor, alpha 0.130179
ELAVL3 ELAV like neuron-specific RNA binding protein 3 0.130104
CTNND1 catenin (cadherin-associated protein), delta 1 0.12905
CYBB cytochrome b-245, beta polypeptide 0.128743
ASPA aspartoacylase 0.127957
ECE1 endothelin converting enzyme 1 0.127529
CTSC cathepsin C 0.127498
FN1 fibronectin 1 0.126926
FOXC1 forkhead box C1 0.126764
PAX3 paired box 3 0.126631