t cell activation Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. (Gene Ontology, GO_0042110)
External Link http://amigo.geneontology.org/amigo/term/GO:0042110
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Genes

199 genes participating in the t cell activation biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ADA adenosine deaminase
ADAM17 ADAM metallopeptidase domain 17
AMICA1 adhesion molecule, interacts with CXADR antigen 1
ANXA1 annexin A1
APC adenomatous polyposis coli
ATP7A ATPase, Cu++ transporting, alpha polypeptide
AZI2 5-azacytidine induced 2
B2M beta-2-microglobulin
BATF basic leucine zipper transcription factor, ATF-like
BAX BCL2-associated X protein
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BCL2 B-cell CLL/lymphoma 2
BCL3 B-cell CLL/lymphoma 3
BLK BLK proto-oncogene, Src family tyrosine kinase
BLM Bloom syndrome, RecQ helicase-like
BRAF B-Raf proto-oncogene, serine/threonine kinase
BTN3A1 butyrophilin, subfamily 3, member A1
CADM1 cell adhesion molecule 1
CASP8 caspase 8, apoptosis-related cysteine peptidase
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CCND3 cyclin D3
CD151 CD151 molecule (Raph blood group)
CD1C CD1c molecule
CD2 CD2 molecule
CD276 CD276 molecule
CD28 CD28 molecule
CD3D CD3d molecule, delta (CD3-TCR complex)
CD3E CD3e molecule, epsilon (CD3-TCR complex)
CD3G CD3g molecule, gamma (CD3-TCR complex)
CD4 CD4 molecule
CD7 CD7 molecule
CD80 CD80 molecule
CD86 CD86 molecule
CD8A CD8a molecule
CD8B CD8b molecule
CDK6 cyclin-dependent kinase 6
CHD7 chromodomain helicase DNA binding protein 7
CLEC4F C-type lectin domain family 4, member F
CLEC7A C-type lectin domain family 7, member A
CRIP3 cysteine-rich protein 3
CRTAM cytotoxic and regulatory T cell molecule
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTPS1 CTP synthase 1
CXADR coxsackie virus and adenovirus receptor
CXCL12 chemokine (C-X-C motif) ligand 12
CXCR4 chemokine (C-X-C motif) receptor 4
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)
DLG1 discs, large homolog 1 (Drosophila)
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3
DOCK2 dedicator of cytokinesis 2
DOCK8 dedicator of cytokinesis 8
DPP4 dipeptidyl-peptidase 4
EGR1 early growth response 1
ELF4 E74-like factor 4 (ets domain transcription factor)
EOMES eomesodermin
F2RL1 coagulation factor II (thrombin) receptor-like 1
FADD Fas (TNFRSF6)-associated via death domain
FKBP1A FK506 binding protein 1A, 12kDa
FKBP1B FK506 binding protein 1B, 12.6 kDa
FOXP1 forkhead box P1
FOXP3 forkhead box P3
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
FYN FYN proto-oncogene, Src family tyrosine kinase
FZD5 frizzled class receptor 5
FZD7 frizzled class receptor 7
FZD8 frizzled class receptor 8
GATA3 GATA binding protein 3
GIMAP1 GTPase, IMAP family member 1
GLI3 GLI family zinc finger 3
HLA-E major histocompatibility complex, class I, E
HSH2D hematopoietic SH2 domain containing
HSPD1 heat shock 60kDa protein 1 (chaperonin)
ICAM1 intercellular adhesion molecule 1
IFNA10 interferon, alpha 10
IFNA14 interferon, alpha 14
IFNA16 interferon, alpha 16
IFNA17 interferon, alpha 17
IFNA21 interferon, alpha 21
IFNA4 interferon, alpha 4
IFNA5 interferon, alpha 5
IFNA6 interferon, alpha 6
IFNA7 interferon, alpha 7
IFNA8 interferon, alpha 8
IFNAR1 interferon (alpha, beta and omega) receptor 1
IFNB1 interferon, beta 1, fibroblast
IFNE interferon, epsilon
IFNG interferon, gamma
IFNK interferon, kappa
IFNW1 interferon, omega 1
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL12B interleukin 12B
IL15 interleukin 15
IL18R1 interleukin 18 receptor 1
IL2 interleukin 2
IL23A interleukin 23, alpha subunit p19
IL4 interleukin 4
IL7R interleukin 7 receptor
INS insulin
IRF1 interferon regulatory factor 1
IRF4 interferon regulatory factor 4
ITGAD integrin, alpha D
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITK IL2-inducible T-cell kinase
JAG2 jagged 2
JMJD6 jumonji domain containing 6
KIF13B kinesin family member 13B
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
LAT linker for activation of T cells
LCK LCK proto-oncogene, Src family tyrosine kinase
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LEF1 lymphoid enhancer-binding factor 1
LIG4 ligase IV, DNA, ATP-dependent
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MALT1 MALT1 paracaspase
MICA MHC class I polypeptide-related sequence A
MICB MHC class I polypeptide-related sequence B
MPZL2 myelin protein zero-like 2
NCK1 NCK adaptor protein 1
NCK2 NCK adaptor protein 2
NCOR1 nuclear receptor corepressor 1
NCSTN nicastrin
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NHEJ1 nonhomologous end-joining factor 1
NKAP NFKB activating protein
NKX2-3 NK2 homeobox 3
NLRC3 NLR family, CARD domain containing 3
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PAX1 paired box 1
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PKNOX1 PBX/knotted 1 homeobox 1
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRLR prolactin receptor
PSEN1 presenilin 1
PSEN2 presenilin 2
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPRC protein tyrosine phosphatase, receptor type, C
RAB27A RAB27A, member RAS oncogene family
RAG1 recombination activating gene 1
RAG2 recombination activating gene 2
RC3H1 ring finger and CCCH-type domains 1
RC3H2 ring finger and CCCH-type domains 2
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RHOH ras homolog family member H
RIPK2 receptor-interacting serine-threonine kinase 2
RIPK3 receptor-interacting serine-threonine kinase 3
RORA RAR-related orphan receptor A
RORC RAR-related orphan receptor C
RPL22 ribosomal protein L22
RPS6 ribosomal protein S6
RSAD2 radical S-adenosyl methionine domain containing 2
RUNX2 runt-related transcription factor 2
SATB1 SATB homeobox 1
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SHH sonic hedgehog
SLA2 Src-like-adaptor 2
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SMAD3 SMAD family member 3
SOX4 SRY (sex determining region Y)-box 4
SP3 Sp3 transcription factor
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
STOML2 stomatin (EPB72)-like 2
STX11 syntaxin 11
TBX21 T-box 21
TCF3 transcription factor 3
TCF7 transcription factor 7 (T-cell specific, HMG-box)
TGFB1 transforming growth factor, beta 1
TNFRSF4 tumor necrosis factor receptor superfamily, member 4
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TNFSF8 tumor necrosis factor (ligand) superfamily, member 8
TP53 tumor protein p53
TREML2 triggering receptor expressed on myeloid cells-like 2
TXK TXK tyrosine kinase
VAV1 vav 1 guanine nucleotide exchange factor
WAS Wiskott-Aldrich syndrome
WNT1 wingless-type MMTV integration site family, member 1
WNT4 wingless-type MMTV integration site family, member 4
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZBTB1 zinc finger and BTB domain containing 1
ZBTB32 zinc finger and BTB domain containing 32
ZFP36L1 ZFP36 ring finger protein-like 1
ZFP36L2 ZFP36 ring finger protein-like 2