systolic heart failure Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
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Genes

85 genes co-occuring with the disease systolic heart failure in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
ACE angiotensin I converting enzyme 1.90056
SHF Src homology 2 domain containing F 1.83863
NPPB natriuretic peptide B 1.61844
NR3C2 nuclear receptor subfamily 3, group C, member 2 1.36335
PDK4 pyruvate dehydrogenase kinase, isozyme 4 0.963728
CRP C-reactive protein, pentraxin-related 0.936214
PDE5A phosphodiesterase 5A, cGMP-specific 0.856087
UCN urocortin 0.834788
CORIN corin, serine peptidase 0.824948
LCN2 lipocalin 2 0.802385
CST3 cystatin C 0.799923
BBS2 Bardet-Biedl syndrome 2 0.728952
NPPA natriuretic peptide A 0.72329
EFS embryonal Fyn-associated substrate 0.710378
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 0.680697
TRIP12 thyroid hormone receptor interactor 12 0.580828
FSTL1 follistatin-like 1 0.55712
WASH7P WAS protein family homolog 7 pseudogene 0.554403
WASH1 WAS protein family homolog 1 0.550522
WASH6P WAS protein family homolog 6 pseudogene 0.547807
TTN titin 0.540442
CPB1 carboxypeptidase B1 (tissue) 0.526518
REN renin 0.524974
IRF7 interferon regulatory factor 7 0.518805
MMP2 matrix metallopeptidase 2 0.504973
TIMP1 TIMP metallopeptidase inhibitor 1 0.499997
SHD Src homology 2 domain containing transforming protein D 0.467306
KLHL17 kelch-like family member 17 0.463905
OPN3 opsin 3 0.445052
ADRB1 adrenoceptor beta 1 0.443923
ADM adrenomedullin 0.442418
GDF15 growth differentiation factor 15 0.440914
CYP2D7 cytochrome P450, family 2, subfamily D, polypeptide 7 (gene/pseudogene) 0.427015
NRG1 neuregulin 1 0.42289
MEA1 male-enhanced antigen 1 0.42214
MIR22 microRNA 22 0.41727
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 0.416896
LGALS3 lectin, galactoside-binding, soluble, 3 0.41465
ACAP3 ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 0.407919
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 0.406798
DDAH1 dimethylarginine dimethylaminohydrolase 1 0.398589
FGF23 fibroblast growth factor 23 0.388909
MMP9 matrix metallopeptidase 9 0.37555
ACE2 angiotensin I converting enzyme 2 0.368518
DNAH8 dynein, axonemal, heavy chain 8 0.362239
MPO myeloperoxidase 0.347144
IL6 interleukin 6 0.342739
CPSF3L cleavage and polyadenylation specific factor 3-like 0.33944
TNF tumor necrosis factor 0.33651
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2 0.325916
FGD1 FYVE, RhoGEF and PH domain containing 1 0.324823
MLX MLX, MAX dimerization protein 0.319363
CMA1 chymase 1, mast cell 0.309566
MMP1 matrix metallopeptidase 1 0.298371
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) 0.293694
TBK1 TANK-binding kinase 1 0.292975
HSPA1B heat shock 70kDa protein 1B 0.290103
HAVCR1 hepatitis A virus cellular receptor 1 0.276158
MME membrane metallo-endopeptidase 0.275089
DAND5 DAN domain family member 5, BMP antagonist 0.263722
MEGF6 multiple EGF-like-domains 6 0.263722
OR10K1 olfactory receptor, family 10, subfamily K, member 1 0.244345
EDN1 endothelin 1 0.238752
RYR2 ryanodine receptor 2 (cardiac) 0.238752
HSPB7 heat shock 27kDa protein family, member 7 (cardiovascular) 0.238403
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1 0.235268
ALB albumin 0.232142
PLN phospholamban 0.225573
FKBP1A FK506 binding protein 1A, 12kDa 0.223165
AVP arginine vasopressin 0.222479
SELE selectin E 0.222479
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.219398
FOXO3 forkhead box O3 0.215992
HAMP hepcidin antimicrobial peptide 0.197099
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 0.189551
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.185612
CHKA choline kinase alpha 0.17952
PPIG peptidylprolyl isomerase G (cyclophilin G) 0.166319
NOTCH1 notch 1 0.164786
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 0.162306
ADIPOR2 adiponectin receptor 2 0.161139
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5 0.160761
EDNRA endothelin receptor type A 0.160021
RETN resistin 0.158605
TNNT2 troponin T type 2 (cardiac) 0.157929