systemic mastocytosis Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
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Genes

168 genes co-occuring with the disease systemic mastocytosis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
FIP1L1 factor interacting with PAPOLA and CPSF1 1.98482
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 1.86369
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 1.71317
TET2 tet methylcytosine dioxygenase 2 1.46232
ISM1 isthmin 1, angiogenesis inhibitor 1.45572
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 1.41709
CMA1 chymase 1, mast cell 1.30488
CHIC2 cysteine-rich hydrophobic domain 2 1.27388
PDGFRB platelet-derived growth factor receptor, beta polypeptide 1.19704
FGFR1 fibroblast growth factor receptor 1 1.18152
VIT vitrin 1.13078
PTGDS prostaglandin D2 synthase 21kDa (brain) 1.11393
GMCL1 germ cell-less, spermatogenesis associated 1 1.10804
MEI1 meiosis inhibitor 1 1.07152
JAK2 Janus kinase 2 1.02735
CD63 CD63 molecule 1.02271
CD34 CD34 molecule 1.00879
IFNA2 interferon, alpha 2 0.978426
KITLG KIT ligand 0.938704
MTSS1 metastasis suppressor 1 0.920085
CLTCL1 clathrin, heavy chain-like 1 0.842573
HDC histidine decarboxylase 0.823718
DESI2 desumoylating isopeptidase 2 0.762271
LYN LYN proto-oncogene, Src family tyrosine kinase 0.760639
PSMC3IP PSMC3 interacting protein 0.758601
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 0.750864
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4 0.749237
PRKG2 protein kinase, cGMP-dependent, type II 0.724098
UBE2B ubiquitin-conjugating enzyme E2B 0.681495
ETV6 ets variant 6 0.656046
SPO11 SPO11 meiotic protein covalently bound to DSB 0.645375
TRIO trio Rho guanine nucleotide exchange factor 0.633169
TNP1 transition protein 1 (during histone to protamine replacement) 0.632777
PDCL2 phosducin-like 2 0.630027
ASXL1 additional sex combs like transcriptional regulator 1 0.62728
TNFRSF8 tumor necrosis factor receptor superfamily, member 8 0.605762
ENPP3 ectonucleotide pyrophosphatase/phosphodiesterase 3 0.60108
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 0.583163
IFNA1 interferon, alpha 1 0.568775
CD68 CD68 molecule 0.557897
GAB2 GRB2-associated binding protein 2 0.554791
SRSF2 serine/arginine-rich splicing factor 2 0.551686
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha 0.546644
SETBP1 SET binding protein 1 0.541605
U2AF1 U2 small nuclear RNA auxiliary factor 1 0.538506
CD2 CD2 molecule 0.537731
CCDC34 coiled-coil domain containing 34 0.521502
CD52 CD52 molecule 0.509192
RUNX1 runt-related transcription factor 1 0.496175
MVD mevalonate (diphospho) decarboxylase 0.493885
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.488549
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.488169
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 0.479427
MITF microphthalmia-associated transcription factor 0.477909
PGM1 phosphoglucomutase 1 0.477151
CAPN1 calpain 1, (mu/I) large subunit 0.469576
WRNIP1 Werner helicase interacting protein 1 0.469197
VAV1 vav 1 guanine nucleotide exchange factor 0.467684
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha 0.461639
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 0.459373
CLEC11A C-type lectin domain family 11, member A 0.45447
ASMT acetylserotonin O-methyltransferase 0.446558
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 0.445429
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.443923
ALPPL2 alkaline phosphatase, placental-like 2 0.440538
ALPP alkaline phosphatase, placental 0.440162
ALPL alkaline phosphatase, liver/bone/kidney 0.439786
CCNC cyclin C 0.436026
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related) 0.42739
GAST gastrin 0.423265
PTBP2 polypyrimidine tract binding protein 2 0.416147
DMRT1 doublesex and mab-3 related transcription factor 1 0.411283
BTK Bruton agammaglobulinemia tyrosine kinase 0.40008
CD44 CD44 molecule (Indian blood group) 0.392629
MUC4 mucin 4, cell surface associated 0.381481
SPN sialophorin 0.377031
ACO1 aconitase 1, soluble 0.365193
MT2A metallothionein 2A 0.35892
MPO myeloperoxidase 0.356709
FLT3 fms-related tyrosine kinase 3 0.355604
BCL2L11 BCL2-like 11 (apoptosis facilitator) 0.350452
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 0.337608
C5AR1 complement component 5a receptor 1 0.331391
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin) 0.33066
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 0.32993
HOXB13 homeobox B13 0.32774
CD69 CD69 molecule 0.318635
PLK2 polo-like kinase 2 0.317182
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 0.315729
FLAD1 flavin adenine dinucleotide synthetase 1 0.31029
MYH11 myosin, heavy chain 11, smooth muscle 0.309204
HRH2 histamine receptor H2 0.304864
CD9 CD9 molecule 0.298011
SEMG1 semenogelin I 0.292257
TNFSF8 tumor necrosis factor (ligand) superfamily, member 8 0.282225
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) 0.277227
FCGRT Fc fragment of IgG, receptor, transporter, alpha 0.275801
ATN1 atrophin 1 0.273308
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.263014
PGF placental growth factor 0.26266
CD5 CD5 molecule 0.257711
DHPS deoxyhypusine synthase 0.253479
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta 0.250663
IL9 interleukin 9 0.249257
PTBP1 polypyrimidine tract binding protein 1 0.247852
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 0.243995
HHAT hedgehog acyltransferase 0.225573
PROP1 PROP paired-like homeobox 1 0.223509
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.223509
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 0.218374
AGA aspartylglucosaminidase 0.210253
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 0.206248
CD59 CD59 molecule, complement regulatory protein 0.195183
CYSLTR2 cysteinyl leukotriene receptor 2 0.187415
TERF1 telomeric repeat binding factor (NIMA-interacting) 1 0.18621
ATM ATM serine/threonine kinase 0.177576
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide 0.172544
SIRPA signal-regulatory protein alpha 0.170054
BTC betacellulin 0.168381
GPR162 G protein-coupled receptor 162 0.166544
UBE2H ubiquitin-conjugating enzyme E2H 0.162908
MLXIPL MLX interacting protein-like 0.160761
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.160203
ATP11A ATPase, class VI, type 11A 0.160203
BANF1 barrier to autointegration factor 1 0.158778
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 0.158605
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.158266
ECE1 endothelin converting enzyme 1 0.137838
PRSS21 protease, serine, 21 (testisin) 0.137719
S1PR1 sphingosine-1-phosphate receptor 1 0.137333
ICK intestinal cell (MAK-like) kinase 0.136999
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 0.136951
AXIN2 axin 2 0.136807
RICTOR RPTOR independent companion of MTOR, complex 2 0.136501
ENG endoglin 0.136285
HAND1 heart and neural crest derivatives expressed 1 0.136063
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1) 0.135406
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.134916
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.134841
CTRL chymotrypsin-like 0.133884
ANPEP alanyl (membrane) aminopeptidase 0.1334
TPMT thiopurine S-methyltransferase 0.133298
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 0.133298
GADD45A growth arrest and DNA-damage-inducible, alpha 0.133059
GLS glutaminase 0.132936
PGRMC1 progesterone receptor membrane component 1 0.132608
MGAM maltase-glucoamylase 0.13202
CLU clusterin 0.131448
NOX4 NADPH oxidase 4 0.130693
CDH5 cadherin 5, type 2 (vascular endothelium) 0.130538
CADM1 cell adhesion molecule 1 0.129547
IL6R interleukin 6 receptor 0.129547
GRB2 growth factor receptor-bound protein 2 0.129248
ANK1 ankyrin 1, erythrocytic 0.128962
ERAS ES cell expressed Ras 0.128783
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 0.127529
CD6 CD6 molecule 0.126997
RNASE3 ribonuclease, RNase A family, 3 0.125557
ANXA5 annexin A5 0.125123
NPHS1 nephrosis 1, congenital, Finnish type (nephrin) 0.124798
BMP2 bone morphogenetic protein 2 0.124524
GLS2 glutaminase 2 (liver, mitochondrial) 0.124493
MBTPS1 membrane-bound transcription factor peptidase, site 1 0.124217
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.122889
DNAH8 dynein, axonemal, heavy chain 8 0.122619
TGFB2 transforming growth factor, beta 2 0.12037
CBS cystathionine-beta-synthase 0.119786
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 0.119309