synaptic vesicle Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A secretory organelle, some 50 nm in diameter, of presynaptic nerve terminals; accumulates in high concentrations of neurotransmitters and secretes these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane. (Gene Ontology, GO_0008021)
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Genes

104 proteins localized to the synaptic vesicle cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
AMPH amphiphysin 0.663342
PPT1 palmitoyl-protein thioesterase 1 0.663342
SEPT5 septin 5 0.663342
DTNBP1 dystrobrevin binding protein 1 0.663342
COPS4 COP9 signalosome subunit 4 0.663342
COPS5 COP9 signalosome subunit 5 0.663342
SNAPIN SNAP-associated protein 0.663342
CLN3 ceroid-lipofuscinosis, neuronal 3 0.663342
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2 0.663342
SYN3 synapsin III 0.663342
SYP synaptophysin 0.663342
DMXL2 Dmx-like 2 0.663342
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) 0.663342
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5 0.663342
SYT4 synaptotagmin IV 0.663342
SYT1 synaptotagmin I 0.663342
TOR1A torsin family 1, member A (torsin A) 0.663342
SV2B synaptic vesicle glycoprotein 2B 0.237908
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6 0.237908
SV2A synaptic vesicle glycoprotein 2A 0.237908
HCRT hypocretin (orexin) neuropeptide precursor 0.237908
SYNGR3 synaptogyrin 3 0.237908
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 0.237908
SYN1 synapsin I 0.237908
TMEM163 transmembrane protein 163 0.237908
MT3 metallothionein 3 0.237908
MME membrane metallo-endopeptidase 0.237908
SYT11 synaptotagmin XI 0.237908
BRSK1 BR serine/threonine kinase 1 0.237908
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1 0.237908
SLC32A1 solute carrier family 32 (GABA vesicular transporter), member 1 0.237908
SLC6A17 solute carrier family 6 (neutral amino acid transporter), member 17 0.237908
TPRG1L tumor protein p63 regulated 1-like 0.237908
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C 0.237908
SLC30A3 solute carrier family 30 (zinc transporter), member 3 0.237908
OTOF otoferlin 0.237908
SLC17A8 solute carrier family 17 (vesicular glutamate transporter), member 8 0.237908
SNCAIP synuclein, alpha interacting protein 0.237908
TRAPPC4 trafficking protein particle complex 4 0.237908
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7 0.237908
ICA1 islet cell autoantigen 1, 69kDa 0.237908
SV2C synaptic vesicle glycoprotein 2C 0.237908
RPH3A rabphilin 3A 0.237908
RAB11B RAB11B, member RAS oncogene family 0.237908
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 0.237908
GIPC1 GIPC PDZ domain containing family, member 1 0.098109
MTMR2 myotubularin related protein 2 0.098109
RAB3A RAB3A, member RAS oncogene family 0.098109
SYNPR synaptoporin 0.098109
RAB5A RAB5A, member RAS oncogene family 0.098109
VTI1A vesicle transport through interaction with t-SNAREs 1A 0.098109
VTI1B vesicle transport through interaction with t-SNAREs 1B 0.098109
DLG4 discs, large homolog 4 (Drosophila) 0.098109
SYPL1 synaptophysin-like 1 0.098109
SYPL2 synaptophysin-like 2 0.098109
SVOP SV2 related protein homolog (rat) 0.098109
CADM1 cell adhesion molecule 1 0.03318
GRIA1 glutamate receptor, ionotropic, AMPA 1 0.03318
STX1A syntaxin 1A (brain) 0.03318
PCLO piccolo presynaptic cytomatrix protein 0.03318
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8 0.03318
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 0.03318
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 0.03318
SNCA synuclein, alpha (non A4 component of amyloid precursor) 0.03318
RAB3B RAB3B, member RAS oncogene family 0.03318
RAB3C RAB3C, member RAS oncogene family 0.03318
SCAMP1 secretory carrier membrane protein 1 0.03318
SYT17 synaptotagmin XVII 0.03318
PI4K2A phosphatidylinositol 4-kinase type 2 alpha 0.03318
SYT10 synaptotagmin X 0.03318
SEPT6 septin 6 0.03318
GRIA2 glutamate receptor, ionotropic, AMPA 2 0.03318
CTTNBP2 cortactin binding protein 2 0.03318
STON2 stonin 2 0.03318
SYN2 synapsin II 0.03318
KIF3A kinesin family member 3A 0.03318
DRD2 dopamine receptor D2 0.03318
SYT7 synaptotagmin VII 0.03318
LRRK2 leucine-rich repeat kinase 2 0.03318
TH tyrosine hydroxylase 0.03318
SYNGR2 synaptogyrin 2 0.03318
TRIM9 tripartite motif containing 9 0.03318
SYT6 synaptotagmin VI 0.03318
SYT5 synaptotagmin V 0.03318
SYT3 synaptotagmin III 0.03318
SYT2 synaptotagmin II 0.03318
SYT9 synaptotagmin IX 0.03318
KCNK9 potassium channel, two pore domain subfamily K, member 9 0.03318
BIN1 bridging integrator 1 0.03318
LGI3 leucine-rich repeat LGI family, member 3 0.03318
CDK16 cyclin-dependent kinase 16 0.03318
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 0.03318
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.03318
SPHK1 sphingosine kinase 1 0.03318
SYNGR1 synaptogyrin 1 0.03318
BDNF brain-derived neurotrophic factor 0.03318
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 0.03318
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 0.03318
SYTL4 synaptotagmin-like 4 0.03318
CACFD1 calcium channel flower domain containing 1 0.03318
DOC2B double C2-like domains, beta 0.03318
DOC2A double C2-like domains, alpha 0.03318
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1 0.03318
SYT8 synaptotagmin VIII 0.03318