sympathetic chain Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description Either of the pair of ganglionated longitudinal cords of the sympathetic nervous system of which one is situated on each side of the spinal column. (BRENDA Tissue and Enzyme Source Ontology, BTO_0001834)
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Genes

322 proteins co-occuring with the tissue sympathetic chain in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
TH tyrosine hydroxylase 2.38694
NGF nerve growth factor (beta polypeptide) 2.31407
NPY neuropeptide Y 2.30026
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 2.08509
TAC1 tachykinin, precursor 1 2.05407
VIP vasoactive intestinal peptide 1.80972
CALCA calcitonin-related polypeptide alpha 1.78336
GAL galanin/GMAP prepropeptide 1.694
ACHE acetylcholinesterase (Yt blood group) 1.67905
GPC3 glypican 3 1.67556
CHAT choline O-acetyltransferase 1.66057
NPS neuropeptide S 1.58782
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) 1.52378
PNMT phenylethanolamine N-methyltransferase 1.32777
SLC18A3 solute carrier family 18 (vesicular acetylcholine transporter), member 3 1.31469
KCNQ2 potassium channel, voltage gated KQT-like subfamily Q, member 2 1.30658
SST somatostatin 1.24833
C11ORF57 chromosome 11 open reading frame 57 1.24476
PIH1D2 PIH1 domain containing 2 1.24476
KNG1 kininogen 1 1.23851
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 1.2109
BCHE butyrylcholinesterase 1.20778
STMN2 stathmin 2 1.1616
PPAPDC2 phosphatidic acid phosphatase type 2 domain containing 2 1.05193
CNTF ciliary neurotrophic factor 1.03346
PDYN prodynorphin 1.00981
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3 0.975449
NTF3 neurotrophin 3 0.970253
AANAT aralkylamine N-acetyltransferase 0.969821
GLTP glycolipid transfer protein 0.969388
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary) 0.960744
TRAPPC9 trafficking protein particle complex 9 0.958585
SYP synaptophysin 0.952978
PCDHA7 protocadherin alpha 7 0.948239
ARTN artemin 0.923767
GDNF glial cell derived neurotrophic factor 0.920771
PHOX2A paired-like homeobox 2a 0.9118
SCN9A sodium channel, voltage gated, type IX alpha subunit 0.907961
CA5B carbonic anhydrase VB, mitochondrial 0.897745
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 0.89562
P2RX3 purinergic receptor P2X, ligand gated ion channel, 3 0.880358
MARCH7 membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase 0.879089
ASCL1 achaete-scute family bHLH transcription factor 1 0.870217
NTS neurotensin 0.860521
NRTN neurturin 0.818576
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein 0.813562
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2 0.809803
REEP2 receptor accessory protein 2 0.807299
GAP43 growth associated protein 43 0.804796
SCGN secretagogin, EF-hand calcium binding protein 0.803961
TACR1 tachykinin receptor 1 0.803961
TTLL7 tubulin tyrosine ligase-like family member 7 0.80271
PPY pancreatic polypeptide 0.787299
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic 0.783557
SCG2 secretogranin II 0.761984
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 0.7595
ATP6V1F ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F 0.754537
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa 0.75247
HAND2 heart and neural crest derivatives expressed 2 0.73803
GRM2 glutamate receptor, metabotropic 2 0.736794
NGFR nerve growth factor receptor 0.725685
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.70845
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.70845
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.707221
UNC13A unc-13 homolog A (C. elegans) 0.699853
KCNK4 potassium channel, two pore domain subfamily K, member 4 0.699035
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog 0.686776
DRGX dorsal root ganglia homeobox 0.683919
ATF3 activating transcription factor 3 0.673728
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 0.672913
BDNF brain-derived neurotrophic factor 0.667622
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 0.651371
SOX10 SRY (sex determining region Y)-box 10 0.646911
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit 0.638404
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.621831
CALB1 calbindin 1, 28kDa 0.616586
CNRIP1 cannabinoid receptor interacting protein 1 0.599273
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit 0.598469
TIMM8B translocase of inner mitochondrial membrane 8 homolog B (yeast) 0.596058
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa 0.583621
ADRB1 adrenoceptor beta 1 0.581218
MOB4 MOB family member 4, phocein 0.571619
CCK cholecystokinin 0.568025
STRN4 striatin, calmodulin binding protein 4 0.565631
GRM4 glutamate receptor, metabotropic 4 0.559652
GNB5 guanine nucleotide binding protein (G protein), beta 5 0.558059
SPATS2L spermatogenesis associated, serine-rich 2-like 0.548517
ENO2 enolase 2 (gamma, neuronal) 0.547326
PNOC prepronociceptin 0.544152
PEG10 paternally expressed 10 0.540981
HOMER2 homer scaffolding protein 2 0.540981
TUBA1A tubulin, alpha 1a 0.540188
FOS FBJ murine osteosarcoma viral oncogene homolog 0.534251
HTRA1 HtrA serine peptidase 1 0.533856
MYO5A myosin VA (heavy chain 12, myoxin) 0.531089
CNR1 cannabinoid receptor 1 (brain) 0.524771
RIMS1 regulating synaptic membrane exocytosis 1 0.523194
MRGPRX1 MAS-related GPR, member X1 0.520829
KCNB2 potassium channel, voltage gated Shab related subfamily B, member 2 0.520435
PENK proenkephalin 0.518859
SYT1 synaptotagmin I 0.518859
GNAQ guanine nucleotide binding protein (G protein), q polypeptide 0.51335
PSD pleckstrin and Sec7 domain containing 0.512564
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.511778
NTF4 neurotrophin 4 0.507457
PCGF1 polycomb group ring finger 1 0.50471
SYN1 synapsin I 0.503141
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F 0.497266
NAALADL1 N-acetylated alpha-linked acidic dipeptidase-like 1 0.493354
SCAMP2 secretory carrier membrane protein 2 0.489447
GRM1 glutamate receptor, metabotropic 1 0.483206
SYBU syntabulin (syntaxin-interacting) 0.474646
NAPA N-ethylmaleimide-sensitive factor attachment protein, alpha 0.47348
MBOAT7 membrane bound O-acyltransferase domain containing 7 0.467273
CAMK2N2 calcium/calmodulin-dependent protein kinase II inhibitor 2 0.465335
CALB2 calbindin 2 0.461852
MTX3 metaxin 3 0.456828
DRG2 developmentally regulated GTP binding protein 2 0.456442
TRPC7 transient receptor potential cation channel, subfamily C, member 7 0.452584
SLC30A7 solute carrier family 30 (zinc transporter), member 7 0.452584
KCNK10 potassium channel, two pore domain subfamily K, member 10 0.448346
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 0.447961
RET ret proto-oncogene 0.444499
PHOX2B paired-like homeobox 2b 0.443347
CBLN3 cerebellin 3 precursor 0.430312
PGLS 6-phosphogluconolactonase 0.429547
NRP1 neuropilin 1 0.429165
CBS cystathionine-beta-synthase 0.427636
SV2A synaptic vesicle glycoprotein 2A 0.423818
HOMER1 homer scaffolding protein 1 0.423818
C1D C1D nuclear receptor corepressor 0.423436
REEP1 receptor accessory protein 1 0.418099
TRH thyrotropin-releasing hormone 0.416195
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 0.413151
OPRL1 opiate receptor-like 1 0.407073
FFAR3 free fatty acid receptor 3 0.402144
JUN jun proto-oncogene 0.399492
SNPH syntaphilin 0.399492
GCG glucagon 0.391931
DLGAP1 discs, large (Drosophila) homolog-associated protein 1 0.389289
KIF5B kinesin family member 5B 0.387781
RIC8A RIC8 guanine nucleotide exchange factor A 0.387781
GNAT1 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 0.387027
PLXNA1 plexin A1 0.38665
LTK leukocyte receptor tyrosine kinase 0.38665
SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B 0.383637
SCN8A sodium channel, voltage gated, type VIII alpha subunit 0.368624
IFT122 intraflagellar transport 122 0.36825
CBLN2 cerebellin 2 precursor 0.367502
RESP18 regulated endocrine-specific protein 18 0.36526
ADCY2 adenylate cyclase 2 (brain) 0.364886
TRPV1 transient receptor potential cation channel, subfamily V, member 1 0.363393
AKAP7 A kinase (PRKA) anchor protein 7 0.360409
KIFAP3 kinesin-associated protein 3 0.356686
GDF5 growth differentiation factor 5 0.35334
SV2C synaptic vesicle glycoprotein 2C 0.352598
SATB2 SATB homeobox 2 0.351485
ADRA2C adrenoceptor alpha 2C 0.342971
ODF2 outer dense fiber of sperm tails 2 0.338914
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 0.33744
HBG2 hemoglobin, gamma G 0.336704
MTX2 metaxin 2 0.330827
POMC proopiomelanocortin 0.329361
B3GAT1 beta-1,3-glucuronyltransferase 1 0.325701
KCNK2 potassium channel, two pore domain subfamily K, member 2 0.32497
EHMT1 euchromatic histone-lysine N-methyltransferase 1 0.322414
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 0.32132
MGAM maltase-glucoamylase 0.320591
UBQLN1 ubiquilin 1 0.320227
SCN3A sodium channel, voltage gated, type III alpha subunit 0.320227
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein 0.319498
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 0.31332
RPIA ribose 5-phosphate isomerase A 0.310421
MYO1B myosin IB 0.308612
COMT catechol-O-methyltransferase 0.301758
INS insulin 0.297806
ELAVL3 ELAV like neuron-specific RNA binding protein 3 0.295297
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5 0.294939
PTGDS prostaglandin D2 synthase 21kDa (brain) 0.293508
MYLK myosin light chain kinase 0.292793
CHGA chromogranin A 0.292793
TEN1 TEN1 CST complex subunit 0.284607
HCRT hypocretin (orexin) neuropeptide precursor 0.281423
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1 0.280012
MAP2 microtubule-associated protein 2 0.277549
ALB albumin 0.275094
TRIM15 tripartite motif containing 15 0.274744
TRIM10 tripartite motif containing 10 0.274045
PAM16 presequence translocase-associated motor 16 homolog (S. cerevisiae) 0.270909
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide 0.264696
INSRR insulin receptor-related receptor 0.262645
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 0.262304
SRRM1 serine/arginine repetitive matrix 1 0.262304
GRM7 glutamate receptor, metabotropic 7 0.261964
IL1RAP interleukin 1 receptor accessory protein 0.261964
ADORA1 adenosine A1 receptor 0.260945
CARTPT CART prepropeptide 0.260267
GRIA4 glutamate receptor, ionotropic, AMPA 4 0.259254
HTR3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic 0.25858
MLX MLX, MAX dimerization protein 0.257237
INTU inturned planar cell polarity protein 0.256234
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8 0.253248
MTX1 metaxin 1 0.251934
SCN10A sodium channel, voltage gated, type X alpha subunit 0.249977
TRIM26 tripartite motif containing 26 0.249653
STRN striatin, calmodulin binding protein 0.245491
GRM5 glutamate receptor, metabotropic 5 0.242672
GALP galanin-like peptide 0.242363
PAM peptidylglycine alpha-amidating monooxygenase 0.241438
NT5E 5'-nucleotidase, ecto (CD73) 0.24052
BNIP2 BCL2/adenovirus E1B 19kDa interacting protein 2 0.23961
TTL tubulin tyrosine ligase 0.23961
BSN bassoon presynaptic cytomatrix protein 0.239007
HTR5A 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled 0.238706
DNM2 dynamin 2 0.238406
GAST gastrin 0.236921
DMD dystrophin 0.236627
SNAPIN SNAP-associated protein 0.235457
DLAT dihydrolipoamide S-acetyltransferase 0.235167
TPTE transmembrane phosphatase with tensin homology 0.235167
GNAS GNAS complex locus 0.232881
GRP gastrin-releasing peptide 0.232039
RACGAP1 Rac GTPase activating protein 1 0.231482
PLXNA4 plexin A4 0.226411
SV2B synaptic vesicle glycoprotein 2B 0.226155
GRM6 glutamate receptor, metabotropic 6 0.226155
AGPS alkylglycerone phosphate synthase 0.224893
KCNK18 potassium channel, two pore domain subfamily K, member 18 0.221989
ASMT acetylserotonin O-methyltransferase 0.221755
ITCH itchy E3 ubiquitin protein ligase 0.216933
CD6 CD6 molecule 0.215534
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 0.214954
KIF1A kinesin family member 1A 0.214765
NCK1 NCK adaptor protein 1 0.214388
PLCB4 phospholipase C, beta 4 0.214202
MAOA monoamine oxidase A 0.214017
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 0.214017
HRH1 histamine receptor H1 0.213112
THY1 Thy-1 cell surface antigen 0.212761
KCNE1 potassium channel, voltage gated subfamily E regulatory beta subunit 1 0.212761
SRGN serglycin 0.190721
CCDC130 coiled-coil domain containing 130 0.188548
SLC7A4 solute carrier family 7, member 4 0.184874
SHANK2 SH3 and multiple ankyrin repeat domains 2 0.184838
ADRA1B adrenoceptor alpha 1B 0.184675
MAOB monoamine oxidase B 0.183935
SYT7 synaptotagmin VII 0.183797
SLC30A3 solute carrier family 30 (zinc transporter), member 3 0.183743
VIPR2 vasoactive intestinal peptide receptor 2 0.183548
PGRMC2 progesterone receptor membrane component 2 0.183548
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 0.183446
BANF1 barrier to autointegration factor 1 0.181026
REXO2 RNA exonuclease 2 0.180418
TMEM132D transmembrane protein 132D 0.179267
RGMB repulsive guidance molecule family member b 0.177163
NOTUM notum pectinacetylesterase homolog (Drosophila) 0.175591
STX8 syntaxin 8 0.172111
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 0.171022
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 0.17078
GGN gametogenetin 0.170632
CADM1 cell adhesion molecule 1 0.170557
TRIM47 tripartite motif containing 47 0.169944
SPON1 spondin 1, extracellular matrix protein 0.169787
CAV2 caveolin 2 0.169107
MN1 meningioma (disrupted in balanced translocation) 1 0.169066
MAPK8 mitogen-activated protein kinase 8 0.168903
ART3 ADP-ribosyltransferase 3 0.168657
TRPM8 transient receptor potential cation channel, subfamily M, member 8 0.168573
PTPRG protein tyrosine phosphatase, receptor type, G 0.166721
ANKRD1 ankyrin repeat domain 1 (cardiac muscle) 0.166237
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 0.164798
BORA bora, aurora kinase A activator 0.164502
SHANK3 SH3 and multiple ankyrin repeat domains 3 0.16425
NCBP1 nuclear cap binding protein subunit 1, 80kDa 0.164096
EDA ectodysplasin A 0.16379
GPR148 G protein-coupled receptor 148 0.163401
NPPA natriuretic peptide A 0.16311
SYT2 synaptotagmin II 0.162413
PDE9A phosphodiesterase 9A 0.162005
BIRC2 baculoviral IAP repeat containing 2 0.160587
PZP pregnancy-zone protein 0.160032
PPT1 palmitoyl-protein thioesterase 1 0.159972
NSF N-ethylmaleimide-sensitive factor 0.156422
DNMT3L DNA (cytosine-5-)-methyltransferase 3-like 0.155716
EEF2 eukaryotic translation elongation factor 2 0.155241
TNS1 tensin 1 0.153548
TNXA tenascin XA (pseudogene) 0.153404
TNXB tenascin XB 0.153404
ACE2 angiotensin I converting enzyme 2 0.150283
KRT86 keratin 86, type II 0.148487
DCPS decapping enzyme, scavenger 0.148446
CAMK2G calcium/calmodulin-dependent protein kinase II gamma 0.146533
WRN Werner syndrome, RecQ helicase-like 0.145022
KCNK9 potassium channel, two pore domain subfamily K, member 9 0.143917
BTNL2 butyrophilin-like 2 0.140405
TSPO translocator protein (18kDa) 0.138423
LAD1 ladinin 1 0.137579
LGALS4 lectin, galactoside-binding, soluble, 4 0.136426
LHX3 LIM homeobox 3 0.134471
NELFCD negative elongation factor complex member C/D 0.134419
GSTA2 glutathione S-transferase alpha 2 0.131552
GSTA1 glutathione S-transferase alpha 1 0.130951
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 0.12863
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 0.12863
WDFY2 WD repeat and FYVE domain containing 2 0.127103
MARS methionyl-tRNA synthetase 0.126246
PRSS21 protease, serine, 21 (testisin) 0.12613
NOS3 nitric oxide synthase 3 (endothelial cell) 0.123092
FKBP4 FK506 binding protein 4, 59kDa 0.122256
GRIA1 glutamate receptor, ionotropic, AMPA 1 0.121956
ISL1 ISL LIM homeobox 1 0.121836
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 0.121716
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like 0.120692
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase 0.120448
NRG1 neuregulin 1 0.118613
TMEM245 transmembrane protein 245 0.118613
COLEC12 collectin sub-family member 12 0.118613
CHGB chromogranin B 0.118179
ADA adenosine deaminase 0.117808
NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa 0.117684
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5 0.117499
VEZF1 vascular endothelial zinc finger 1 0.11675