suxibuzone-2503 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the suxibuzone-2503 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABHD2 abhydrolase domain containing 2
ABLIM1 actin binding LIM protein 1
ADAM22 ADAM metallopeptidase domain 22
AGGF1 angiogenic factor with G patch and FHA domains 1
AKAP8L A kinase (PRKA) anchor protein 8-like
ALDOB aldolase B, fructose-bisphosphate
ALOXE3 arachidonate lipoxygenase 3
ALX4 ALX homeobox 4
AMACR alpha-methylacyl-CoA racemase
ANGPTL2 angiopoietin-like 2
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
B9D1 B9 protein domain 1
BFSP1 beaded filament structural protein 1, filensin
BMP1 bone morphogenetic protein 1
CACNB4 calcium channel, voltage-dependent, beta 4 subunit
CALML3 calmodulin-like 3
CCDC88A coiled-coil domain containing 88A
CDC14A cell division cycle 14A
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CYP4F8 cytochrome P450, family 4, subfamily F, polypeptide 8
DKK3 dickkopf WNT signaling pathway inhibitor 3
FAM65A family with sequence similarity 65, member A
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FLJ11292
FOXO4 forkhead box O4
FSD1 fibronectin type III and SPRY domain containing 1
GAB1 GRB2-associated binding protein 1
GPR161 G protein-coupled receptor 161
GRHL2 grainyhead-like 2 (Drosophila)
GRK5 G protein-coupled receptor kinase 5
GSN gelsolin
GULP1 GULP, engulfment adaptor PTB domain containing 1
HCFC1 host cell factor C1
IGFBP5 insulin-like growth factor binding protein 5
ITGB5 integrin, beta 5
KIAA0513 KIAA0513
KLF12 Kruppel-like factor 12
KLHL22 kelch-like family member 22
LPAR3 lysophosphatidic acid receptor 3
LRP5 low density lipoprotein receptor-related protein 5
LTA lymphotoxin alpha
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MCF2 MCF.2 cell line derived transforming sequence
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MEG3 maternally expressed 3 (non-protein coding)
MISP mitotic spindle positioning
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1)
NR4A2 nuclear receptor subfamily 4, group A, member 2
OR12D3 olfactory receptor, family 12, subfamily D, member 3
OTOF otoferlin
PDE8B phosphodiesterase 8B
PDLIM5 PDZ and LIM domain 5
PEG10 paternally expressed 10
PHC1 polyhomeotic homolog 1 (Drosophila)
PHF20L1 PHD finger protein 20-like 1
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4
PITX2 paired-like homeodomain 2
PLA2G3 phospholipase A2, group III
POMT2 protein-O-mannosyltransferase 2
PORCN porcupine homolog (Drosophila)
POU6F2 POU class 6 homeobox 2
PPP1R2P9 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PRKCE protein kinase C, epsilon
PSG1 pregnancy specific beta-1-glycoprotein 1
PVR poliovirus receptor
RB1 retinoblastoma 1
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RUNX1 runt-related transcription factor 1
SCHIP1 schwannomin interacting protein 1
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SETBP1 SET binding protein 1
SH2D1A SH2 domain containing 1A
SLC17A2 solute carrier family 17, member 2
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SPTAN1 spectrin, alpha, non-erythrocytic 1
SSTR5 somatostatin receptor 5
SYCP2 synaptonemal complex protein 2
TADA3 transcriptional adaptor 3
TAOK2 TAO kinase 2
TAT tyrosine aminotransferase
TEKT2 tektin 2 (testicular)
TLR5 toll-like receptor 5
TMEM259 transmembrane protein 259
TPMT thiopurine S-methyltransferase
TRPC2 transient receptor potential cation channel, subfamily C, member 2, pseudogene
TRPC3 transient receptor potential cation channel, subfamily C, member 3
UNC93A unc-93 homolog A (C. elegans)
USP27X ubiquitin specific peptidase 27, X-linked
VASH2 vasohibin 2
VNN1 vanin 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
XYLB xylulokinase homolog (H. influenzae)
ZNF442 zinc finger protein 442
ZNF688 zinc finger protein 688

decreased expression

Symbol Name
ADAM15 ADAM metallopeptidase domain 15
ADAM23 ADAM metallopeptidase domain 23
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALS2CL ALS2 C-terminal like
AMDHD2 amidohydrolase domain containing 2
ARID5A AT rich interactive domain 5A (MRF1-like)
ASAP1-IT1 ASAP1 intronic transcript 1
ASPN asporin
AXIN1 axin 1
B3GNT1
BEX1 brain expressed, X-linked 1
C5 complement component 5
CD70 CD70 molecule
CHML choroideremia-like (Rab escort protein 2)
CHMP7 charged multivesicular body protein 7
CLCF1 cardiotrophin-like cytokine factor 1
COL19A1 collagen, type XIX, alpha 1
DAD1 defender against cell death 1
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DGAT1 diacylglycerol O-acyltransferase 1
DHRS11 dehydrogenase/reductase (SDR family) member 11
DUSP8 dual specificity phosphatase 8
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FHOD1 formin homology 2 domain containing 1
FJX1 four jointed box 1 (Drosophila)
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GCH1 GTP cyclohydrolase 1
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GSTA4 glutathione S-transferase alpha 4
GUSBP3 glucuronidase, beta pseudogene 3
IFT140 intraflagellar transport 140
INHBE inhibin, beta E
INO80D INO80 complex subunit D
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
IPO8 importin 8
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KIAA0319L KIAA0319-like
KIAA0355 KIAA0355
KLF1 Kruppel-like factor 1 (erythroid)
KRT81 keratin 81, type II
LGALS1 lectin, galactoside-binding, soluble, 1
LINC00339 long intergenic non-protein coding RNA 339
LRRC20 leucine rich repeat containing 20
LZTR1 leucine-zipper-like transcription regulator 1
MAVS mitochondrial antiviral signaling protein
METTL2B methyltransferase like 2B
MFSD12 major facilitator superfamily domain containing 12
MLPH melanophilin
MMP9 matrix metallopeptidase 9
NHEJ1 nonhomologous end-joining factor 1
NNAT neuronatin
NOD1 nucleotide-binding oligomerization domain containing 1
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
OXTR oxytocin receptor
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PIEZO1 piezo-type mechanosensitive ion channel component 1
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
PLTP phospholipid transfer protein
POLDIP2 polymerase (DNA-directed), delta interacting protein 2
POLL polymerase (DNA directed), lambda
POM121L2 POM121 transmembrane nucleoporin-like 2
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PROL1 proline rich, lacrimal 1
QTRT1 queuine tRNA-ribosyltransferase 1
RAB3A RAB3A, member RAS oncogene family
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RPS21 ribosomal protein S21
SGMS1 sphingomyelin synthase 1
SLC12A9 solute carrier family 12, member 9
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SND1-IT1 SND1 intronic transcript 1
SPATA1 spermatogenesis associated 1
SPATA2L spermatogenesis associated 2-like
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STBD1 starch binding domain 1
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TBC1D17 TBC1 domain family, member 17
TBL3 transducin (beta)-like 3
TEC tec protein tyrosine kinase
TMEM110 transmembrane protein 110
TMEM120B transmembrane protein 120B
TMEM184C transmembrane protein 184C
TMEM53 transmembrane protein 53
TNS2 tensin 2
TRIM45 tripartite motif containing 45
TRIM68 tripartite motif containing 68
XYLT2 xylosyltransferase II
YY2 YY2 transcription factor
ZC3H12A zinc finger CCCH-type containing 12A
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF232 zinc finger protein 232
ZNF304 zinc finger protein 304
ZNF37BP zinc finger protein 37B, pseudogene
ZNF696 zinc finger protein 696